onchocerciasis

Summary
Synonym
  • Infection by Onchocerca volvulus
  • Onchocerca volvulus infection
  • volvulosis
Definition
A filariasis that involves parasitic infection caused by the nematode Onchocerca volvulus, which is transmitted to humans through the bite of a blackfly of the genus Simulium. The worms spread throughout the body and, when they die, cause intense itching and a strong immune system response that can destroy nearby tissue. The symptoms include pruritus, dermatitis, blindness, onchocercomata (subcutaneous nodules), and lymphadenopathy.
Super Class
filariasis
External Links
Disease Ontology
DOID:11678
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
GARD
Related Genes
Displaying all 2 entries
Gene ID Gene Symbol Description Source
811 CALR calreticulin
27306 HPGDS hematopoietic prostaglandin D synthase
Related Glycoprotein
Displaying all 2 entries
UniProt ID Protein Name Source
O60760 Hematopoietic prostaglandin D synthase
P27797 Calreticulin

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024