Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
Resources Genes Glycoproteins Lectins Glycolipids Glycans Pathways Diseases Organisms
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Other Information
Release Statistics Download
Tools
SugarDrawer GlycanBuilder Glycan Converters GlycoMaple GlycomeAtlas LM-GlycomeAtlas GALAXY MCAW GlycoSim GRable
Search Tools
Cross Search Glycan Search Publication Search Programmatic Access
Standards Ontologies Notations
multiple sclerosis

Summary
Synonym
  • Generalized multiple sclerosis
  • insular sclerosis
Definition
A demyelinating disease that involves damage to the fatty myelin sheaths around the axons of the brain and spinal cord resulting in demyelination and scarring.
Super Class
autoimmune disease of central nervous system demyelinating disease
External Links
Disease Ontology
DOID:2377
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
GARD
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 121 - 130 of 170 in total
Gene ID Gene Symbol Description Source
8809 IL18R1 interleukin 18 receptor 1
8821 INPP4B inositol polyphosphate-4-phosphatase type II B
8877 SPHK1 sphingosine kinase 1
8879 SGPL1 sphingosine-1-phosphate lyase 1
9023 CH25H cholesterol 25-hydroxylase
9331 B4GALT6 beta-1,4-galactosyltransferase 6
9334 B4GALT5 beta-1,4-galactosyltransferase 5
9365 KL klotho
9370 ADIPOQ adiponectin, C1Q and collagen domain containing
9374 PPT2 palmitoyl-protein thioesterase 2
Displaying all 7 entries
Gene ID Gene Symbol Description Source
11450 Adipoq adiponectin, C1Q and collagen domain containing
16002 Igf2 insulin-like growth factor 2
21898 Tlr4 toll-like receptor 4
21926 Tnf tumor necrosis factor
56336 B4galt5 UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5
56386 B4galt6 UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 6
100198 H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
Displaying all 5 entries
Gene ID Gene Symbol Description Source
24483 Igf2 insulin-like growth factor 2
24835 Tnf tumor necrosis factor
29260 Tlr4 toll-like receptor 4
65196 B4galt6 beta-1,4-galactosyltransferase 6
362275 B4galt5 beta-1,4-galactosyltransferase 5
Displaying all 3 entries
Gene ID Gene Symbol Description Source
36585 beta4GalNAcTA beta1,4-N-acetylgalactosaminyltransferase A
43222 Tl Toll
43425 beta4GalNAcTB beta1,4-N-acetylgalactosaminyltransferase B
Displaying all 2 entries
Gene ID Gene Symbol Description Source
393912 b4galt6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
724080 b4galt5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
Displaying all 6 entries
Gene ID Gene Symbol Description Source Organism
446703 b4galt5.L UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 L homeolog Xenopus laevis (African clawed frog)
548965 b4galt6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 Xenopus tropicalis (tropical clawed frog)
549139 b4galt5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 Xenopus tropicalis (tropical clawed frog)
779435 b4galt6.L UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 L homeolog Xenopus laevis (African clawed frog)
108695277 b4galt6.S UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 S homeolog Xenopus laevis (African clawed frog)
108702589 b4galt5.S UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 S homeolog Xenopus laevis (African clawed frog)
Displaying 1 entry
Gene ID Gene Symbol Description Source
190668 bre-4 Beta-1,4-N-acetylgalactosaminyltransferase bre-4
Displaying 1 entry
Gene ID Gene Symbol Description Source
856294 RHO1 Rho family GTPase RHO1
Related Glycoprotein
About Release Notes Help Feedback

Click here to visit the beta site.

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

Logo License Policies Site Map

Contact: support@glycosmos.org

This work is licensed under Creative Commons Attribution 4.0 International

GlyCosmos Portal v4.0.0

Last updated: August 19, 2024