heart valve disease

Summary
Synonym
  • Valvular heart disease
Definition
A heart disease involving one or more of the four valves of the heart (the aortic and mitral valves on the left and the pulmonary and tricuspid valves on the right).
Super Class
heart disease
Disease Ontology
DOID:4079
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying all 8 entries
Gene ID Gene Symbol Description Source
1278 COL1A2 collagen type I alpha 2 chain
1636 ACE angiotensin I converting enzyme
2589 GALNT1 polypeptide N-acetylgalactosaminyltransferase 1
3357 HTR2B 5-hydroxytryptamine receptor 2B
4041 LRP5 LDL receptor related protein 5
4313 MMP2 matrix metallopeptidase 2
4318 MMP9 matrix metallopeptidase 9
7124 TNF tumor necrosis factor
Displaying all 8 entries
Gene ID Gene Symbol Description Source
11421 Ace angiotensin I converting enzyme
12843 Col1a2 collagen, type I, alpha 2
14423 Galnt1 polypeptide N-acetylgalactosaminyltransferase 1
15559 Htr2b 5-hydroxytryptamine (serotonin) receptor 2B
16973 Lrp5 low density lipoprotein receptor-related protein 5
17390 Mmp2 matrix metallopeptidase 2
17395 Mmp9 matrix metallopeptidase 9
21926 Tnf tumor necrosis factor
Displaying all 7 entries
Gene ID Gene Symbol Description Source
24310 Ace angiotensin I converting enzyme
24835 Tnf tumor necrosis factor
29581 Htr2b 5-hydroxytryptamine receptor 2B
79214 Galnt1 polypeptide N-acetylgalactosaminyltransferase 1
81686 Mmp2 matrix metallopeptidase 2
81687 Mmp9 matrix metallopeptidase 9
84352 Col1a2 collagen type I alpha 2 chain
Displaying all 3 entries
Gene ID Gene Symbol Description Source
34189 Acer Angiotensin-converting enzyme-related
34805 Ance Angiotensin converting enzyme
326151 Pgant5 Polypeptide N-Acetylgalactosaminyltransferase 5
Displaying all 2 entries
Gene ID Gene Symbol Description Source
559073 galnt1 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1
565980 ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
Displaying all 2 entries
Gene ID Gene Symbol Description Source Organism
594943 galnt1 polypeptide N-acetylgalactosaminyltransferase 1 Xenopus tropicalis (tropical clawed frog)
100144634 ace angiotensin I converting enzyme Xenopus tropicalis (tropical clawed frog)
Displaying all 4 entries
Gene ID Gene Symbol Description Source
176112 gly-3 Polypeptide N-acetylgalactosaminyltransferase 3
179991 zmp-4 Hemopexin;Peptidase metallopeptidase domain-containing protein
180351 W01F3.2 Uncharacterized protein
180780 acn-1 Inactive angiotensin-converting enzyme-related protein

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024