bronchiectasis

Summary
Synonym
  • Polynesian bronchiectasis
Definition
A bronchial disease that is a chronic inflammatory condition of one or more bronchi or bronchioles marked by dilatation and loss of elasticity of the walls resulting from damage to the airway wall leading to the formation of small sacs on the bronchial wall and impairment of cilia mobility in the lung. Inflammation of the bronchial wall increases mucus secretion which serves as a breeding ground for bacteria. Bronchiectasis is caused by repeated respiratory infections, immune deficiency disorders, hereditary disorders (cystic fibrosis or primary ciliary dyskinesia), mechanical factors (inhaled object or a lung tumor) or inhaling toxic substances.
Super Class
bronchial disease
External Links
Disease Ontology
DOID:9563
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
ORDO
OMIM
Related Genes
Displaying entries 11 - 20 of 20 in total
Gene ID Gene Symbol Description Source
7124 TNF tumor necrosis factor
10998 SLC27A5 solute carrier family 27 member 5
50863 NTM neurotrimin
51477 ISYNA1 inositol-3-phosphate synthase 1
56963 RGMA repulsive guidance molecule BMP co-receptor a
83666 PARP9 poly(ADP-ribose) polymerase family member 9
92579 G6PC3 glucose-6-phosphatase catalytic subunit 3
653509 SFTPA1 surfactant protein A1
729238 SFTPA2 surfactant protein A2
100507436 MICA MHC class I polypeptide-related sequence A
Displaying 1 entry
Gene ID Gene Symbol Description Source
21926 Tnf tumor necrosis factor
Displaying 1 entry
Gene ID Gene Symbol Description Source
24835 Tnf tumor necrosis factor

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Last updated: August 19, 2024