GlyCosmos Portal

GlyCosmos Diseases

List of diseases involving glycan related genes. The information of each database of Glyco-Disease Genes Database (GDGDB), DisGeNET, and Alliance of Genome Resources is integrated into one list.

Database	Last Updated
Alliance of Genome Resources	February 28, 2024
DisGeNET	February 14, 2024
Glyco-Disease Genes Database (GDGDB)	January 25, 2017

Disease ID	Disease Name	Gene Symbol ▼	Gene ID
DOID:0081112	Baraitser-Winter syndrome 1	ACT1 ACTA1 ACTA2 ACTB ACTC1 ACTG1 ACTG2 Act42A Act57B Act5C Act79B Act87E Act88F Acta1 Acta1 Acta2 Acta2 Actb Actb Actc1 Actc1 Actg1 Actg1 Actg1l1 Actg2 Actg2 MGC75582 act-1 act-4 acta4 actb.L actb.S actb1 actb2 actb actc1 actg1	100361457 108703086 11459 11461 11464 11465 11468 11475 179535 180767 25365 287876 29275 29437 31521 35526 37368 394673 394698 394957 394982 398459 40444 407952 41885 48632 57934 57935 58 59 60 70 71 72 81633 81822 850504
DOID:14004	thoracic aortic aneurysm	ACT1 ACTA1 ACTA2 ACTB ACTC1 ACTG1 ACTG2 Act42A Act57B Act5C Act79B Act87E Act88F Acta1 Acta1 Acta2 Acta2 Actb Actb Actc1 Actc1 Actg1 Actg1 Actg1l1 Actg2 Actg2 MGC75582 THSD4 Thsd4 act-1 act-4 acta4 actb1 actb2 actb actc1 actg1	100361457 11459 11461 11464 11465 11468 11475 179535 180767 207596 25365 287876 29275 29437 31521 35526 37368 394673 394698 394957 394982 40444 407952 41885 48632 57934 57935 58 59 60 70 71 72 79875 81633 81822 850504
DOID:13099	Moyamoya disease	ACT1 ACTA1 ACTA2 ACTB ACTC1 ACTG1 ACTG2 Act42A Act57B Act5C Act79B Act87E Act88F Acta1 Acta1 Acta2 Acta2 Actb Actb Actc1 Actc1 Actg1 Actg1 Actg1l1 Actg2 Actg2 MGC75582 RNF213 act-1 act-4 acta4 actb1 actb2 actb actc1 actg1	100361457 11459 11461 11464 11465 11468 11475 179535 180767 25365 287876 29275 29437 31521 35526 37368 394673 394698 394957 394982 40444 407952 41885 48632 57674 57934 57935 58 59 60 70 71 72 81633 81822 850504
DOID:13832	patent ductus arteriosus	ACT1 ACTA1 ACTA2 ACTB ACTC1 ACTG1 ACTG2 Act42A Act57B Act5C Act79B Act87E Act88F Acta1 Acta1 Acta2 Acta2 Actb Actb Actc1 Actc1 Actg1 Actg1 Actg1l1 Actg2 Actg2 MGC75582 RECK act-1 act-4 acta4 actb1 actb2 actb actc1 actg1	100361457 11459 11461 11464 11465 11468 11475 179535 180767 25365 287876 29275 29437 31521 35526 37368 394673 394698 394957 394982 40444 407952 41885 48632 57934 57935 58 59 60 70 71 72 81633 81822 8434 850504
DOID:0050567	orofacial cleft	ACSS2	55902
DOID:11981	morbid obesity	ACSS2 CYP2E1 LPIN1 Lpin1 MEST PAH1	14245 1571 23175 4232 55902 855201
DOID:3319	lymphangioleiomyomatosis	ACSS2 CPT1A GAPDH GLS Gls Gls glna-2 glna-3	1374 14660 172547 174282 24398 2597 2744 55902
DOID:1574	alcohol use disorder	ACSS2 ADH5 ALDH2 ARF6 Arf6 Arf6 COMT CYP2E1 FADS1 FADS2 GAD1 GAD2 HDAC1 HDAC2 Hdac2 N NCAM1 PIK3CB PIK3CD PPP1R3B PPP1R3C PSPH Psph Psph RAC1 RAC3 RPD3 Rac1 Rac1 Rac3 SER2 SHMT1 SHMT2 ST6GAL1 SiaT St6gal1 St6gal1 aay hda-1 st6gal1.L st6gal1.S st6gal1 st6gal1	100491268 100678 108717116 108718183 11845 128 1312 15182 1571 170758 179959 19353 20440 217 25197 2571 2572 304429 3066 31293 363875 37950 382 38565 39085 3992 445376 4684 5291 5293 5507 55902 5723 5879 5881 6470 6472 6480 79121 79660 853122 855386 9415
DOID:9282	ocular hypertension	ACSM3 MGM1 OPA1 Opa1 Opa1 TPI1 TPI1 opa1	171116 492332 4976 6296 7167 74143 851620 854386
DOID:10825	essential hypertension	ACSM3 CAT CYP3A5 HSD11B1 HSD11B2 MFN2 MTHFD1 PIK3CA PIK3CB PIK3CD PIK3CG PTGIS SHMT1	1577 3290 3291 4522 5290 5291 5293 5294 5740 6296 6470 847 9927