GlyCosmos Portal

GlyCosmos Diseases

List of diseases involving glycan related genes. The information of each database of Glyco-Disease Genes Database (GDGDB), DisGeNET, and Alliance of Genome Resources is integrated into one list.

Database	Last Updated
Alliance of Genome Resources	February 28, 2024
DisGeNET	February 14, 2024
Glyco-Disease Genes Database (GDGDB)	January 25, 2017

Disease ID	Disease Name	Gene Symbol ▼	Gene ID
DOID:4001	ovarian carcinoma	ABHD8 BI4 CDH13 GBGT1 HDAC3 HOS2 HRAS HS3ST2 Hdac3 Hdac3 IGF2R L1CAM MRC1 OPCML PTEN RHO1 RHO2 RHOA Rhoa Rhoa STS TNFRSF10C TUSC3 hda-2 hdac3.S hdac3 hdac3	1012 117273 11848 15183 174285 26301 3265 3482 387 3897 393965 412 432017 4360 4978 549637 5728 79575 7991 84578 852681 854582 855634 856294 8794 8841 9956
DOID:2394	ovarian cancer	ABHD8 ANXA7 ATG26 C25G4.2 CALR CDH13 CG5412 CHI3L1 COMT CTS2 CYP19A1 Calr GBGT1 HDAC3 HOS2 HPRT1 HRAS HS3ST2 Hdac3 Hdac3 ICAM1 IGF2R Idgf1 Idgf2 Idgf3 Idgf4 MBL2 MRC1 MSLN OGG1 OGG1 OPCML OVCA2 Ogg1 Ogg1 Ogg1 Ovca2 PIK3CA POL2 POLE PRSS8 PTEN PTGS1 PolE1 Pole Rrp1 SHMT1 STS TEP1 TNFRSF10C TUSC3 TYMP Tymp Tymp UGT1A1 Ugt1a1 Ugt1a1 Ugt301D1 Ugt302K1 Ugt303A1 Ugt304A1 Ugt316A1 Ugt35A1 Ugt35C1 Ugt35E2 Ugt36D1 Ugt36E1 Ugt36F1 Ugt37A3 Ugt37C1 Ugt37D1 Ugt37E1 Ugt49B2 cht-1 hda-2 hdac3.S hdac3 hdac3 ovca2 ugt-61 ugt1a1 ugt1a6 ugt1a7 ugt1ab	100135191 100384891 100489505 1012 10232 1116 124641 1312 15183 1588 174285 178194 180628 18294 185500 1890 18973 246257 24861 26301 310 315219 31806 31926 3251 3265 33500 3383 3482 34978 34979 34981 35105 35137 35138 35139 393965 394436 40079 406731 41166 412 41334 4153 41574 42434 42538 42758 432017 4360 4968 4978 5290 53501 53502 53503 53506 53507 53511 53512 53583 5426 54658 549637 553576 5652 5728 5742 6470 72962 79575 7991 811 81528 84578 850886 851977 852681 854942 855459 855595 8794 8841 9956
DOID:0050729	Chanarin-Dorfman syndrome	ABHD4 Abhd4 CLD1 PNPLA2 PNPLA3 PNPLA5 Pnpla2 Pnpla2 Pnpla3 Pnpla5 abhd-5.2 atgl-1	105501 116939 150379 175910 178877 361676 57104 63874 66853 75772 80339 853007
DOID:0112342	hereditary spastic paraplegia 86	ABHD16A Abhd16a Abhd16a	193742 361796 7920
DOID:0080181	PHARC syndrome	ABHD12 Abhd12 Abhd12 abhd12 abhd12	100216158 26090 499913 76192 767657
DOID:3910	lung adenocarcinoma	ABCE1 AKR1A1 Abce1 CALR CD44 CLEC14A CYP24A1 Calr EEF2 EFT1 Eef2 Eef2 GPX3 HRAS IDH1 IDH2 IGF2R KRAS Kras Kras Lerp N PLC1 PLCG1 Plcg1 Plcg1 Plod Ras85D SAMHD1 SDC1 SULF2 Sdc eEF2 eef2.1.L eef2b plc-3	10327 13629 1591 161198 16653 174586 18803 1938 24015 24525 25738 25939 2878 29565 31293 3265 326929 3417 3418 3482 35422 37447 380348 3845 39265 41140 41166 43223 5335 55959 6059 6382 811 851993 855860 960
DOID:526	human immunodeficiency virus infectious disease	ABCE1 AICDA Abce1 Aicda CD209 CYP2B6 MBL2 PLA2G2A PLAUR PTGS2 Pla2g2a Pla2g2a SAMHD1 SELP	11628 1555 18780 24015 25939 29692 30835 4153 5320 5329 57379 5743 6059 6403
DOID:684	hepatocellular carcinoma	ABCE1 ACE ACER3 ACTB ADE4 AKR1B1 ALDH2 ALDH7A1 ALDOC APRT APT1 APT2 ARG1 Abce1 Acer3 Aprt Aprt Aprt Arg1 Arg1 CAD CALR CAR1 CAT CDH13 CYP2C19 CYP2E1 Cad Calr Ces1f ERN1 Ern1 FHIT FUT6 Fhit Fhit G6PC1 G6PD G6pc1 G6pc1 GAPDH GGT1 GPC1 GPC3 GPX1 GPX3 HDAC1 HDAC1 HDAC2 HDAC4 HDAC5 HJV HK2 HMGCS2 HNT2 HPGDS HPRT1 HRAS HSPA5 Hdac2 Hdac4 Hdac4 Hprt1 Hprt1 Hras Hras ICAM1 IDH2 IGF2R IL18R1 INSR IRE1 Il18r1 KLRK1 KRAS Kras Kras Lerp MBL2 MEST MRC1 MTHFD2 Mthfd2 NEIL3 NRAS Neil3 Nmdmc Nras OGT PAFAH1B1 PIK3CA PIK3CB PLAAT4 PLAUR PLC1 PLCG1 PLOD3 PNPLA3 PON1 PPAT PRKAA2 PTEN PTGS2 Plcg1 Plcg1 Plod3 Plod3 Plod Pnpla3 PolG1 Pon1 Pon1 Ppat Ppat Prat R09H10.3 RAC1 RGN RIT1 RPD3 Rac1 Rac1 Ras85D Rgn Rgn Rit1 Rrp1 SMC3 SMC3 SMC3 SOAT2 SRD5A2 SULF1 TEP1 TIGAR YDC1 YPC1 ZK697.8 aprt-1 atgl-1 daf-2 dally dlp hda-1 hda-4 ire-1 neil3.L nras.L plc-3 plod3.L plod3 plod3 pyr-1 r rgn rgn	10014 100380996 1012 10797 116939 117544 11821 11846 14198 14377 148738 15182 15452 15461 1557 1571 16182 1636 16653 172232 174305 174385 174586 175410 175910 17768 179959 181723 187757 18803 18979 191414 19353 19733 19769 2081 208727 217 2272 22914 230 231 231327 23213 234258 234564 24015 24465 24525 24605 25106 2528 2538 2539 25634 25738 2597 26433 2678 2719 27306 2817 2876 2878 288583 292072 29221 293621 3065 3066 3099 3158 3251 32627 32640 3265 3309 33500 3383 3418 34792 3482 353 363287 363875 3643 380138 383 3845 38565 39013 39265 39596 399446 403070 40935 41140 41166 4153 4232 43223 4360 448549 47895 48224 4893 501 5048 5290 5291 5329 5335 5444 5471 55247 55331 556077 5563 57103 5728 5743 5879 5920 60 6016 60398 6059 66190 6716 69719 734090 78943 790 80339 811 84024 8435 847 8473 851899 852051 852481 853371 854986 855346 855386 855595 855860 855993 856018 856478 8809 8985 9104 9126 9759
DOID:0111066	congenital bile acid synthesis defect 5	ABCD3 Abcd3 Abcd3	19299 25270 5825
DOID:905	Zellweger syndrome	ABCD3 Abcd3 Abcd3 PEX1 PEX1 Pex1 SCP2	19299 25270 5189 5825 6342 71382 853636