GlyCosmos Portal

GlyCosmos Diseases

List of diseases involving glycan related genes. The information of each database of Glyco-Disease Genes Database (GDGDB), DisGeNET, and Alliance of Genome Resources is integrated into one list.

Database	Last Updated
Alliance of Genome Resources	February 28, 2024
DisGeNET	February 14, 2024
Glyco-Disease Genes Database (GDGDB)	January 25, 2017

Disease ID	Disease Name ▼	Gene Symbol	Gene ID
DOID:12577	urethral obstruction	CYP19A1	1588
DOID:5199	ureteral obstruction	ACE ARG1 ARG2 Arg1 Arg1 Arg2 Arg2 CAR1 CAT CYP2J2 HSD11B2 HSPA5 Hsc70-3 Hspa5 Hspa5 ICAM1 KAR2 PARP1 Parp1 Parp1 SOAT1 parp-1 parp1	11846 11847 142 14828 1573 1636 25591 25617 266823 29215 29221 32133 3291 3309 3355109 3383 383 384 560788 6646 847 853418 855993
DOID:4676	uremia	AGL ALPL Alpl Alpl COMT GDB1 PHO8	11647 1312 178 249 25586 852092 856314
DOID:8577	ulcerative colitis	ACSM3 ALOX12 ALPI Alox12 Alppl2 CYP24A1 GPX1 GPX2 ICAM1 PHO8 PON1 PON3 PTGS1 PTGS2 Pon1 Pon1 Pon3 Pon3 RHO1 RHOA Rhoa Rhoa SELL SELP daf-2	11650 11684 117273 11848 1591 175410 18979 239 248 269823 2876 2877 312086 3383 387 5444 5446 5742 5743 6296 6402 6403 84024 852092 856294
DOID:0050726	tyrosinemia type I	FAH Fah Fah fah-1	14085 180918 2184 29383
DOID:9352	type 2 diabetes mellitus	AAH1 ACE ACOT2 ADA AKR1B1 ALDH2 ALDOB ALOX12 ATG26 Ada Ada Alox12 BI4 C27A7.3 CAT CD38 CEL CHI3L1 CPT1A CTS2 CYB5R4 CYP11A1 CYP11B2 CYP1A1 CYP2C19 CYP2C8 CYP2C9 CYP2E1 Cd38 Cd38 DAG1 DCN DNM1 DNM1L Dg Dnm1l Dnm1l ENPP1 Enpp1 Enpp1 FOL2 FUCA1 FZO1 Fuca1 Fuca1 Fuca G6PC1 G6PD G6pc1 G6pc1 GCH1 GCK GCKR GFPT1 GFPT2 GGT1 GLO1 GLO1 GPD2 GPX3 Gch1 Gch1 Gckr Gckr HK2 HPSE HSD11B1 HSD11B2 HSD17B3 HSD3B1 ICAM1 IGF2R INPPL1 INSR Idgf1 Idgf2 Idgf3 Idgf4 Inppl1 Inppl1 KL Kl Kl LIPC LIPE LPL Lerp Lipc Lipe Lipe Lpl Lpl MFN2 Marf Mfn2 NAMPT NPP1 NPP2 Nampt Nampt OGA OGG1 OGG1 OGT OXCT1 Oga Oga Oga Ogg1 Ogg1 Ogg1 Ogt Ogt PARP1 PCK1 PDHX PIK3C2A PIK3C2G PIK3CB PIK3CD PKLR PLA2G7 PLAUR PNPLA3 PON1 PON2 PPP1R3A PPP1R3C PRKAA2 PTGDS PTGIS PTGS2 Parp1 Parp1 Pla2g7 Pnpla3 Pon1 Pon1 Pon2 Pon2 Pu REG3G SDC2 SDHB SELL SELP SLC2A2 SLC2A3 SLC2A4 SNF1 SPHK1 SRD5A1 Sdc UGT1A10 UGT1A1 UGT1A6 UGT1A7 UGT1A8 UGT1A9 Ugt1a1 Ugt1a1 Ugt1a6 Ugt1a6a Ugt1a6b Ugt1a7c Ugt1a7c Ugt301D1 Ugt302K1 Ugt303A1 Ugt304A1 Ugt316A1 Ugt35A1 Ugt35C1 Ugt35D1 Ugt35E1 Ugt35E2 Ugt36A1 Ugt36D1 Ugt36E1 Ugt36F1 Ugt37A2 Ugt37A3 Ugt37B1 Ugt37C1 Ugt37C2 Ugt37D1 Ugt37E1 Ugt49B1 Ugt49B2 Ugt50B3 VCAM1 W03G11.3 ada.S ada ada ar atgl-1 cat-4 cht-1 daf-2 dnm1l drp-1 enpp-1 fzo-1 gckr.L inppl1a ogt-1 ogt.1 ogt paf-2 parp-1 parp1 rho-7 sxc ugt-62 ugt1a1 ugt1a6 ugt1a7 ugt1ab	100 100135191 100384891 100489505 10059 10135 1056 10724 108155 10855 10965 1116 113992 114114 11486 11684 116939 12494 130120 1374 142 14377 14528 1543 15450 154516 154968 1557 1558 1559 1571 1583 1585 1605 16332 1634 1636 16591 16890 16956 170731 173990 175410 175591 175910 176000 177336 179472 179663 179665 180628 180704 18294 18605 189173 18979 217 229 231 231103 239 24165 24375 24539 246614 24861 2517 25330 2538 2539 25591 25634 25658 25668 26295 2643 2645 2646 266823 2673 2678 27226 2739 2820 2878 29244 296851 297508 3099 31581 31806 31926 325179 3283 3290 3291 3293 330260 3355109 337685 3383 3482 34978 34979 34981 35105 35137 35138 35139 35486 36281 3636 3643 36773 37415 37420 37447 3772574 393896 394432 394435 394436 398839 3990 3991 40079 4023 406731 41334 41573 41574 42518 42538 43223 436919 43708 44058 444167 496434 4968 5019 5105 51167 5167 5286 5288 5291 5293 5313 5329 53501 53502 53503 53504 53506 53507 53511 53512 53513 53583 53584 5444 5445 54575 54576 54577 54578 54600 54658 5506 5507 553157 5563 560788 564156 5730 5740 5743 59027 6383 6390 6402 6403 65038 6514 6515 6517 6715 71665 74006 7412 76055 7941 80339 8050 81528 83504 84024 847 8473 850391 850686 850886 851977 852088 852477 853183 854582 854942 85496 855009 855581 856699 8877 9365 94284 952 9927 9945
DOID:9744	type 1 diabetes mellitus	ACE ACHE ALDH2 ATG26 CD14 CD38 CEL CHI3L1 CLEC16A CTS2 CYP27B1 CYP2E1 CYP2R1 Cd38 Cd38 FADS2 FUCA1 Fuca1 Fuca1 Fuca G6PD GAD2 GPX3 HDAC1 HDAC1 HDAC2 HDAC3 HOS2 HSD11B2 Hdac1 Hdac1 Hdac2 Hdac3 Hdac3 ICAM1 IGF2R IL1R1 Idgf1 Idgf2 Idgf3 Idgf4 Il1r1 LGALS3 LIPC Lerp Lipc MBL2 NCAM1 PON1 Pon1 Pon1 RAN RPD3 Ran Ran SELE SELL UGT1A1 Ugt1a1 Ugt1a1 Ugt301D1 Ugt302K1 Ugt303A1 Ugt304A1 Ugt316A1 Ugt35A1 Ugt35C1 Ugt35E2 Ugt36A1 Ugt36D1 Ugt36E1 Ugt36F1 Ugt37A2 Ugt37A3 Ugt37B1 Ugt37C1 Ugt37D1 Ugt37E1 Ugt49B1 Ugt49B2 VCAM1 W03G11.3 XYLT1 Xylt1 Xylt1 cht-1 hda-1 hda-2 hdac1.L hdac3.S hdac3 hdac3 oxt ran.L ran.S ran ran sqv-6 ugt-62 ugt1a1 ugt1a6 ugt1a7 ugt1ab xylt1.L xylt1.S xylt1 xylt1	100135191 100145490 100384891 100489505 1056 108703114 108716335 1116 120227 12494 15182 15183 15450 1571 1594 16177 1636 174285 175591 179959 180628 189173 18979 190099 19384 217 23274 233781 24375 24861 2517 2539 25668 2572 2878 297893 30572 3065 3066 31926 3291 3383 3482 34978 34979 34981 35105 35137 35138 35139 3554 37420 3772574 379874 38288 38565 393965 394436 3958 397868 3990 40079 406731 41334 4153 41573 41574 42538 43 432017 43223 433759 44058 444363 448091 4684 53501 53502 53503 53506 53507 53511 53512 53583 53584 5444 54658 549637 560951 5901 6401 6402 64131 64133 71665 7412 84024 84509 84578 850886 851977 852681 855386 8841 929 9415 952
DOID:1214	tympanosclerosis	C27A7.3 CAT ENPP1 Enpp1 Enpp1 NPP1 NPP2 enpp-1	179663 179665 18605 5167 847 850391 85496 856699
DOID:4929	tubular adenocarcinoma	CDH13 FHIT HPGDS KRAS TNFRSF10C	1012 2272 27306 3845 8794
DOID:13515	tuberous sclerosis	APRT PIK3CA PIK3CB PIK3CD PIK3CG	353 5290 5291 5293 5294