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Guidelines

MIRAGE

membrane integral NOTCH2 associated receptor 2

Summary

Gene Symbol

MINAR2

Organism

Homo sapiens (human)

External Links

NCBI Gene

100127206

PubChem

100127206

Alliance of Genome Resources

HGNC:33914

Annotation

Keyword

Disease variant
Endoplasmic reticulum
Glycoprotein
Lysosome
Non-syndromic deafness
Phosphoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P59773	Major intrinsically disordered NOTCH2-associated receptor 2 Membrane integral NOTCH2-associated receptor 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

1

2

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GO Term	Evidence Code	PMID
angiogenesis	IMP	35727972
sensory perception of sound	IEA
gene expression	IEA
exploration behavior	IEA
inner ear auditory receptor cell differentiation	IEA

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular process [inference]

cell death [inference]

programmed cell death [inference]

apoptotic process [inference]

neuron apoptotic process

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation [inference]

hair cell differentiation [inference]

inner ear auditory receptor cell differentiation

mechanoreceptor differentiation [inference]

inner ear receptor cell differentiation [inference]

inner ear auditory receptor cell differentiation

epithelial cell differentiation [inference]

epidermal cell differentiation [inference]

hair cell differentiation [inference]

inner ear auditory receptor cell differentiation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

inner ear receptor cell stereocilium organization

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of mechanical stimulus [inference]

sensory perception of sound

behavior [inference]

locomotory behavior [inference]

walking behavior

exploration behavior

multicellular organismal-level homeostasis [inference]

homeostasis of number of cells [inference]

homeostasis of number of cells within a tissue

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

homeostasis of number of cells within a tissue

developmental process [inference]

anatomical structure formation involved in morphogenesis [inference]

angiogenesis

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation [inference]

hair cell differentiation [inference]

inner ear auditory receptor cell differentiation

mechanoreceptor differentiation [inference]

inner ear receptor cell differentiation [inference]

inner ear auditory receptor cell differentiation

epithelial cell differentiation [inference]

epidermal cell differentiation [inference]

hair cell differentiation [inference]

inner ear auditory receptor cell differentiation

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

homeostasis of number of cells [inference]

homeostasis of number of cells within a tissue

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

homeostasis of number of cells within a tissue

chemical homeostasis [inference]

lipid homeostasis [inference]

sterol homeostasis [inference]

cholesterol homeostasis

Displaying **all 4** entries
GO Term	Evidence Code	PMID
lysosomal membrane	ISS
endoplasmic reticulum	IDA	32954300
endoplasmic reticulum membrane	IEA
stereocilium	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

bounding membrane of organelle [inference]

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

stereocilium

actin-based cell projection [inference]

stereocilium

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein binding	IPI	32954300
cholesterol binding	IDA	36317962

GO Hierarchy

molecular function

binding [inference]

protein binding

lipid binding [inference]

steroid binding [inference]

sterol binding [inference]

cholesterol binding

small molecule binding [inference]

alcohol binding [inference]

cholesterol binding

organic cyclic compound binding [inference]

steroid binding [inference]

sterol binding [inference]

cholesterol binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Major intrinsically disordered Notch2-binding receptor 1-like

Functional Category

G: Carbohydrate transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
InterPro
Major intrinsically disordered Notch2-binding receptor 1-like, C-terminal
Major intrinsically disordered Notch2-binding receptor 1-like

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0050565	autosomal recessive nonsyndromic deafness	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 57 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	225583	Xenbase:XB-GENE-980432	MOUSE23261
Rattus norvegicus	291580		RATNO13321
Macaca mulatta	708269		MACMU38257
Bos taurus	789687		BOVIN33050
Monodelphis domestica	100022088		MONDO28764
Xenopus tropicalis	100127206	Xenbase:XB-GENE-980432
Oryctolagus cuniculus	100351140		RABIT09281
Callithrix jacchus	100392506		CALJA27175
Pongo abelii	100443730		PONAB29382
Cavia porcellus	100713497		CAVPO03875

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

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Last updated: August 4, 2025