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blood vessel epicardial substance

Summary

Gene Symbol

bves

Organism

Xenopus tropicalis (tropical clawed frog)

External Links

NCBI Gene

100144641

PubChem

100144641

Alliance of Genome Resources

Xenbase:XB-GENE-484277

Annotation

Keyword

Cell adhesion
Cell membrane
Developmental protein
Glycoprotein
Reference proteome
Tight junction
Transmembrane helix
cAMP-binding

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A8J0SKL8
B1H1G2	Popeye domain-containing protein 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
response to ischemia	ISS
regulation of cell shape	ISS
heart development	IBA ISS
vesicle-mediated transport	ISS
skeletal muscle tissue development	IBA ISS

GO Hierarchy

biological process

cellular process [inference]

cell-substrate adhesion [inference]

substrate adhesion-dependent cell spreading

cell-cell adhesion [inference]

epithelial cell-cell adhesion

vesicle-mediated transport

cellular developmental process [inference]

cell differentiation [inference]

muscle cell differentiation [inference]

striated muscle cell differentiation

developmental process [inference]

anatomical structure development [inference]

tissue development [inference]

muscle tissue development [inference]

skeletal muscle tissue development

animal organ development [inference]

heart development

cellular developmental process [inference]

cell differentiation [inference]

muscle cell differentiation [inference]

striated muscle cell differentiation

response to stimulus [inference]

response to stress [inference]

response to ischemia

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of receptor recycling

regulation of macromolecule metabolic process [inference]

regulation of receptor recycling [inference]

positive regulation of receptor recycling

positive regulation of macromolecule metabolic process [inference]

positive regulation of receptor recycling

regulation of signaling [inference]

regulation of receptor recycling [inference]

positive regulation of receptor recycling

positive regulation of signaling [inference]

positive regulation of receptor recycling

regulation of locomotion [inference]

positive regulation of locomotion

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of receptor recycling

positive regulation of signaling [inference]

positive regulation of receptor recycling

positive regulation of locomotion

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of cell morphogenesis [inference]

regulation of cell shape

regulation of biological quality [inference]

regulation of molecular function [inference]

regulation of catalytic activity [inference]

regulation of hydrolase activity [inference]

regulation of GTPase activity

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
membrane	IEA ISS
sarcolemma	IBA IEA ISS
lateral plasma membrane	IEA ISS
plasma membrane	IEA ISS
bicellular tight junction	IEA ISS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

plasma membrane

sarcolemma

plasma membrane region [inference]

plasma membrane raft [inference]

caveola

membrane microdomain [inference]

membrane raft [inference]

plasma membrane raft [inference]

caveola

lateral plasma membrane

cell junction [inference]

anchoring junction [inference]

cell-cell junction [inference]

tight junction [inference]

bicellular tight junction

Displaying **all 2** entries
GO Term	Evidence Code	PMID
structural molecule activity	ISS
cAMP binding	IBA IEA

GO Hierarchy

molecular function

structural molecule activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

cyclic nucleotide binding [inference]

cAMP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

ion binding [inference]

anion binding [inference]

cAMP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

cyclic nucleotide binding [inference]

cAMP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

blood vessel epicardial substance

Functional Category

J: Translation, ribosomal structure and biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
cAMP binding
regulation of membrane potential
striated muscle cell differentiation

Displaying **all 2** entries
InterPro
Cyclic nucleotide-binding domain superfamily
Popeye protein

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0110290	autosomal recessive limb-girdle muscular dystrophy type 2X	Alliance of Genome Resources
DOID:6419	tetralogy of Fallot	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **193** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	11149	9606_0:000898	HGNC:1152
Mus musculus	23828		MGI:1346013
Drosophila melanogaster	33083		FB:FBgn0031150
Rattus norvegicus	365603		RGD:1561100
Xenopus laevis	394408	8355_0:004232	Xenbase:XB-GENE-6254222
Gallus gallus	408032	9031_0:0010a9
Danio rerio	415107		ZFIN:ZDB-GENE-040624-11
Canis lupus familiaris	481944	9615_0:002049
Bos taurus	539988	9913_0:001d4e
Macaca mulatta	696255	9544_0:0013de

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024