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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
peptidylglycine alpha-amidating monooxygenase
Summary
- Gene Symbol
-
- pam
- Organism
- Xenopus tropicalis (tropical clawed frog)
Annotation
- Keyword
-
- Calcium
- Copper
- Cytoplasmic vesicle
- Disulfide bond
- Glycoprotein
- Lyase
- Metal-binding
- Monooxygenase
- Multifunctional enzyme
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Zinc
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A8J0QFI1 |
|
| A0A6I8RMI2 |
|
| A0A6I8SAV5 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| peptide metabolic process |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| cytoplasmic vesicle | ||
| membrane | ||
| transport vesicle membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| lyase activity | ||
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen | ||
| metal ion binding | ||
| peptidylamidoglycolate lyase activity | ||
| copper ion binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- peptidyl-glycine alpha-amidating monooxygenase
- Functional Category
-
- E: Amino acid transport and metabolism
- K: Transcription
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| catalytic activity |
| lyase activity |
| metal ion binding |
| peptide metabolic process |
| peptidylglycine monooxygenase activity |
| InterPro |
|---|
| NHL repeat |
| Peptidylglycine alpha-hydroxylating monooxygenase/peptidyl-hydroxyglycine alpha-amidating lyase |
| Six-bladed beta-propeller, TolB-like |
Disease
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 104041486 | 9209_0:000e4e | |||
| 104044911 | 9209_0:001bb3 | |||
| 104058390 | 55661_0:003f6e | |||
| 104074433 | 30455_0:001465 | |||
| 104078398 | 30455_0:00263b | |||
| 104135057 | 188379_0:00088d | |||
| 104140158 | 441894_0:000f7d | |||
| 104158631 | 54380_0:0011fd | |||
| 104279353 | 57397_0:0034df | |||
| 104292311 | 50402_0:003141 |
