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CD74 molecule

Summary

Gene Symbol

CD74

Organism

Pongo abelii (Sumatran orangutan)

External Links

NCBI Gene: 100171468
KEGG Gene ID: pon:100171468
PubChem: 100171468

Annotation

Keyword

Disulfide bond
Reference proteome
Secreted
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A2J8X648
Q5RFJ4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 13 in total

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2

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GO Term	Evidence Code	PMID
positive regulation of cytokine-mediated signaling pathway	IEA	30032202
T cell activation involved in immune response	IEA	30032202
positive regulation of type 2 immune response	IEA	30032202
intracellular protein transport	IEA	22301074
immune response	IEA	22301074

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response

leukocyte activation [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response

lymphocyte activation [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response

T cell activation [inference]

T cell activation involved in immune response

cellular process [inference]

cell activation [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response

leukocyte activation [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response

lymphocyte activation [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response

T cell activation [inference]

T cell activation involved in immune response

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein trimerization

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein trimerization

multicellular organismal process [inference]

cell activation [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response

leukocyte activation [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response

lymphocyte activation [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response

T cell activation [inference]

T cell activation involved in immune response

response to stimulus [inference]

immune response

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

intracellular protein transport

organic substance transport [inference]

protein transport [inference]

intracellular protein transport

nitrogen compound transport [inference]

protein transport [inference]

intracellular protein transport

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of immune response [inference]

positive regulation of type 2 immune response

regulation of immune effector process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

positive regulation of macrophage cytokine production

regulation of immune response [inference]

regulation of type 2 immune response [inference]

positive regulation of type 2 immune response

positive regulation of immune response [inference]

positive regulation of type 2 immune response

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

positive regulation of macrophage cytokine production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

positive regulation of macrophage cytokine production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of kinase activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of kinase activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

positive regulation of macrophage cytokine production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

positive regulation of macrophage cytokine production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of kinase activity

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of kinase activity

regulation of kinase activity [inference]

positive regulation of kinase activity

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of kinase activity

regulation of nitrogen compound metabolic process [inference]

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

positive regulation of macrophage cytokine production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

positive regulation of macrophage cytokine production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of cytokine-mediated signaling pathway [inference]

positive regulation of cytokine-mediated signaling pathway

positive regulation of signal transduction [inference]

positive regulation of cytokine-mediated signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of ERK1 and ERK2 cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of signal transduction by p53 class mediator [inference]

regulation of DNA damage response, signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intracellular signal transduction [inference]

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of intrinsic apoptotic signaling pathway [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of cytokine-mediated signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of immune response [inference]

positive regulation of type 2 immune response

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of kinase activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of cytokine-mediated signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of cytokine-mediated signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of kinase activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of cytokine-mediated signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of immune response [inference]

positive regulation of type 2 immune response

positive regulation of response to cytokine stimulus [inference]

positive regulation of cytokine-mediated signaling pathway

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of cytokine-mediated signaling pathway [inference]

positive regulation of cytokine-mediated signaling pathway

positive regulation of signal transduction [inference]

positive regulation of cytokine-mediated signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of ERK1 and ERK2 cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of signal transduction by p53 class mediator [inference]

regulation of DNA damage response, signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intracellular signal transduction [inference]

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of intrinsic apoptotic signaling pathway [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of cytokine-mediated signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of immune response [inference]

positive regulation of type 2 immune response

positive regulation of response to cytokine stimulus [inference]

positive regulation of cytokine-mediated signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of immune response [inference]

regulation of type 2 immune response [inference]

positive regulation of type 2 immune response

positive regulation of immune response [inference]

positive regulation of type 2 immune response

regulation of response to cytokine stimulus [inference]

regulation of cytokine-mediated signaling pathway [inference]

positive regulation of cytokine-mediated signaling pathway

positive regulation of response to cytokine stimulus [inference]

positive regulation of cytokine-mediated signaling pathway

regulation of response to stress [inference]

regulation of cellular response to stress [inference]

regulation of DNA damage response, signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of cytokine-mediated signaling pathway [inference]

positive regulation of cytokine-mediated signaling pathway

positive regulation of signal transduction [inference]

positive regulation of cytokine-mediated signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of ERK1 and ERK2 cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of signal transduction by p53 class mediator [inference]

regulation of DNA damage response, signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intracellular signal transduction [inference]

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of intrinsic apoptotic signaling pathway [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of cytokine-mediated signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of kinase activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

positive regulation of macrophage cytokine production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

positive regulation of macrophage cytokine production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of kinase activity

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of kinase activity

regulation of kinase activity [inference]

positive regulation of kinase activity

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of kinase activity

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of cytokine-mediated signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of kinase activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of cellular response to stress [inference]

regulation of DNA damage response, signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

positive regulation of macrophage cytokine production

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of molecular function [inference]

positive regulation of molecular function [inference]

positive regulation of catalytic activity [inference]

positive regulation of transferase activity [inference]

positive regulation of kinase activity

regulation of catalytic activity [inference]

positive regulation of catalytic activity [inference]

positive regulation of transferase activity [inference]

positive regulation of kinase activity

regulation of transferase activity [inference]

regulation of kinase activity [inference]

positive regulation of kinase activity

positive regulation of transferase activity [inference]

positive regulation of kinase activity

Displaying **all 3** entries
GO Term	Evidence Code	PMID
cytoplasm	IEA	30032202
cell surface	IEA	30032202
membrane	IEA	22301074

GO Hierarchy

cellular component

cellular anatomical entity [inference]

Displaying **all 3** entries
GO Term	Evidence Code	PMID
cytokine receptor activity	IEA	30032202
macrophage migration inhibitory factor binding	IEA	22301074 30032202
MHC class II protein binding	IEA	22301074 30032202

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

MHC protein binding [inference]

MHC class II protein binding

cytokine binding [inference]

macrophage migration inhibitory factor binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

cytokine receptor activity

immune receptor activity [inference]

cytokine receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
InterPro
Thyroglobulin type-1 superfamily
Thyroglobulin type-1

KEGG BRITE Database

Orthology

K06505

Name

CD74 antigen

References

Ortholog

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Species	Gene ID	Orthologous MAtrix
Homo sapiens	972	HUMAN81720
Mus musculus	16149	MOUSE23317
Rattus norvegicus	25599	RATNO13665
Danio rerio	58113	DANRE07465
Sus scrofa	396660	PIGXX20108
Pan troglodytes	462191	PANTR36575
Canis lupus familiaris	479329	CANLF14919
Bos taurus	613384	BOVIN33755
Macaca mulatta	710820	MACMU38055
Monodelphis domestica	100029179	MONDO09096

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

International Collaboration

Acknowledgements