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Standards Ontologies Notations
cytochrome P450, family 1, subfamily A, polypeptide 2

Summary
Gene Symbol
  • CYP1A2
Organism
Pongo abelii (Sumatran orangutan)
External Links
NCBI Gene
100172368
KEGG Gene ID
pon:100172368
PubChem
100172368
Annotation
Keyword
  • Fatty acid metabolism
  • Glycoprotein
  • Heme
  • Lyase
  • Membrane
  • Microsome
  • Monooxygenase
  • Reference proteome
  • Sterol metabolism
Proteins
Displaying 1 entry
UniProt Protein Name
Q5RBQ1
  • CYPIA2
  • Cholesterol 25-hydroxylase
  • Hydroperoxy icosatetraenoate dehydratase
Annotation information from UniProt.
Gene Ontology (GO)
Displaying all 2 entries
GO Term Evidence Code PMID
hormone biosynthetic process
progesterone metabolic process
GO Hierarchy
Displaying all 5 entries
GO Term Evidence Code PMID
steroid 17-alpha-monooxygenase activity
iron ion binding
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
17-alpha-hydroxyprogesterone aldolase activity
heme binding
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
KEGG BRITE Database
Orthology
K07409
Name
cytochrome P450 family 1 subfamily A2 [EC:1.14.14.1]
References
Rhea

RHEA:55556

a hydroperoxyeicosatetraenoate
an oxoeicosatetraenoate + H2O
Enzyme
PMID

RHEA:37943

(12R)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate
H2O + 12-oxo-(5Z,8Z,10E,14Z)-eicosatetraenoate
Enzyme
PMID

RHEA:37927

(8S)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate
H2O + 8-oxo-(5Z,9E,11Z,14Z)-eicosatetraenoate
Enzyme
PMID

RHEA:48636

(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate
H2O + 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate
Enzyme
PMID

RHEA:37935

(8R)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate
H2O + 8-oxo-(5Z,9E,11Z,14Z)-eicosatetraenoate
Enzyme
PMID

RHEA:37947

(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate
H2O + 12-oxo-(5Z,8Z,10E,14Z)-eicosatetraenoate
Enzyme
PMID

RHEA:17149

an organic molecule + O2
H2O + H+ + an alcohol
Enzyme
PMID
Ortholog
Displaying entries 1 - 10 of 60 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
103188936 CALMI04314
102357693 LATCH14891
140634 DANRE14017
103038575 ASTMX07068
100136916 SALSA95269
115167062 SALTR82080
115203260 SALTR79523
100125806 ORYLA12681
100706338 ORENI35403
115580898 SPAAU26810
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024