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exostosin glycosyltransferase 1

Summary

Gene Symbol

EXT1

Organism

Pongo abelii (Sumatran orangutan)

External Links

NCBI Gene: 100172450
KEGG Gene ID: pon:100172450
PubChem: 100172450

Annotation

Keyword

Disulfide bond
Endoplasmic reticulum
Glycoprotein
Glycosyltransferase
Golgi apparatus
Manganese
Metal-binding
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q5RBC3	N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process
protein glycosylation	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

macromolecule metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

macromolecule glycosylation [inference]

protein glycosylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
endoplasmic reticulum
endoplasmic reticulum membrane
catalytic complex
membrane	IEA	22301074
Golgi apparatus

GO Hierarchy

cellular component

protein-containing complex [inference]

catalytic complex

cellular anatomical entity [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

bounding membrane of organelle [inference]

Golgi membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Displaying **all 4** entries
GO Term	Evidence Code	PMID
glycosyltransferase activity	IEA	22301074 30032202
glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity
metal ion binding
N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity

UDP-glycosyltransferase activity [inference]

acetylglucosaminyltransferase activity [inference]

glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity

glucuronosyltransferase activity [inference]

N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity

hexosyltransferase activity [inference]

acetylglucosaminyltransferase activity [inference]

glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity

glucuronosyltransferase activity [inference]

N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K02366

Name

glucuronyl/N-acetylglucosaminyl transferase EXT1 [EC:2.4.1.224 2.4.1.225]

References

9665133

Reactions

Displaying **all 2** entries
KEGG Reaction	Enzyme	Acceptor	Product
R10138	2.4.1.225	G18844FT	G70244WB
R05935	2.4.1.225	G13581JW	G74553IH

Rhea

UDP-α-D-glucuronate

H⁺ + UDP

Enzyme

2.4.1.225

PMID

Ortholog

Displaying entries **61 - 70** of 71 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Anabas testudineus	113153482		ANATE05041
Sinocyclocheilus grahami	107592940		SINGR37448
Echeneis naucrates	115050656		ECHNA19033
Salarias fasciatus	115380876		SALFA49393
Cynoglossus semilaevis	103394040		CYNSE13666
Propithecus coquereli	105812176		PROCO21428
Cyprinus carpio carpio	109050531		CYPCA110557
Cyprinus carpio carpio	109109198		CYPCA76766
Nannospalax galili	103738135		NANGA02764
Corvus moneduloides	116454882		CORMO09681

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Last updated: August 19, 2024