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ER lipid raft associated 2

Summary

Gene Symbol

ERLIN2

Organism

Pongo abelii (Sumatran orangutan)

External Links

NCBI Gene: 100173353
PubChem: 100173353

Annotation

Keyword

Acetylation
Cholesterol metabolism
Endoplasmic reticulum
Glycoprotein
Reference proteome
Signal
Signal-anchor
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A0A2J8TPB0	Endoplasmic reticulum lipid raft-associated protein Stomatin-prohibitin-flotillin-HflC/K domain-containing protein
Q5R7C5	Endoplasmic reticulum lipid raft-associated protein 2 Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2
A0A2J8TPC1	Endoplasmic reticulum lipid raft-associated protein Stomatin-prohibitin-flotillin-HflC/K domain-containing protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cholesterol metabolic process
SREBP signaling pathway	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

sterol metabolic process [inference]

cholesterol metabolic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

secondary alcohol metabolic process [inference]

cholesterol metabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

sterol metabolic process [inference]

cholesterol metabolic process

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

sterol metabolic process [inference]

cholesterol metabolic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

secondary alcohol metabolic process [inference]

cholesterol metabolic process

sterol metabolic process [inference]

cholesterol metabolic process

cellular process [inference]

signal transduction [inference]

ER-nucleus signaling pathway [inference]

SREBP signaling pathway

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to sterol depletion [inference]

SREBP signaling pathway

response to stimulus [inference]

response to stress [inference]

response to sterol depletion [inference]

cellular response to sterol depletion [inference]

SREBP signaling pathway

cellular response to stress [inference]

cellular response to sterol depletion [inference]

SREBP signaling pathway

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to sterol depletion [inference]

SREBP signaling pathway

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

ER-nucleus signaling pathway [inference]

SREBP signaling pathway

Displaying **all 2** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	IEA	30032202
endoplasmic reticulum	IEA	22301074 30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cholesterol binding	IEA	30032202
ubiquitin protein ligase binding	IEA	22301074 30032202

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

enzyme binding [inference]

ubiquitin-like protein ligase binding [inference]

ubiquitin protein ligase binding

lipid binding [inference]

steroid binding [inference]

sterol binding [inference]

cholesterol binding

small molecule binding [inference]

alcohol binding [inference]

cholesterol binding

organic cyclic compound binding [inference]

steroid binding [inference]

sterol binding [inference]

cholesterol binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

uncharacterized protein

Functional Category

O: Posttranslational modification, protein turnover, chaperones
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
cholesterol binding
ubiquitin protein ligase binding

Displaying **all 3** entries
InterPro
Band 7 domain
Band 7/SPFH domain superfamily
Erlin1/2

Ortholog

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Homo sapiens	11160	9606_1:0024b5	HUMAN93383
Mus musculus	244373		MOUSE59613
Rattus norvegicus	290823		RATNO10963
Pan troglodytes	464112	9598_0:0025a8	PANTR42352
Canis lupus familiaris	607518		CANLF04700
Bos taurus	616278		BOVIN22087
Ornithorhynchus anatinus	100082208		ORNAN22464
Danio rerio	100151163		DANRE36955
Ciona intestinalis	100176028		CIOIN03537
Sus scrofa	100233180		PIGXX09180