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triggering receptor expressed on myeloid cells 1

Summary

Gene Symbol

TREM1

Organism

Pongo abelii (Sumatran orangutan)

External Links

NCBI Gene: 100174314
PubChem: 100174314

Annotation

Keyword

Adaptive immunity
Cell membrane
Disulfide bond
Glycoprotein
Immunoglobulin domain
Innate immunity
Receptor
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A2J8Y401
Q5RDA5

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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2

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GO Term	Evidence Code	PMID
adaptive immune response
cytokine production involved in immune response	IEA	30032202
neutrophil chemotaxis	IEA	30032202
chemokine production	IEA	30032202
innate immune response

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

leukocyte mediated immunity [inference]

leukocyte mediated cytotoxicity [inference]

neutrophil mediated cytotoxicity [inference]

neutrophil-mediated killing of symbiont cell [inference]

neutrophil-mediated killing of bacterium [inference]

neutrophil-mediated killing of gram-negative bacterium

myeloid leukocyte mediated immunity [inference]

neutrophil mediated immunity [inference]

neutrophil mediated cytotoxicity [inference]

neutrophil-mediated killing of symbiont cell [inference]

neutrophil-mediated killing of bacterium [inference]

neutrophil-mediated killing of gram-negative bacterium

production of molecular mediator of immune response [inference]

cytokine production involved in immune response

immune response [inference]

leukocyte migration [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

myeloid leukocyte migration [inference]

granulocyte migration [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

neutrophil migration [inference]

neutrophil chemotaxis

metabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

cytokine production [inference]

production of molecular mediator of immune response [inference]

cytokine production involved in immune response

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

cytokine production [inference]

production of molecular mediator of immune response [inference]

cytokine production involved in immune response

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

cytokine production [inference]

production of molecular mediator of immune response [inference]

cytokine production involved in immune response

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

cytokine production [inference]

production of molecular mediator of immune response [inference]

cytokine production involved in immune response

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

cytokine production [inference]

production of molecular mediator of immune response [inference]

cytokine production involved in immune response

cellular process [inference]

cell killing [inference]

leukocyte mediated cytotoxicity [inference]

neutrophil mediated cytotoxicity [inference]

neutrophil-mediated killing of symbiont cell [inference]

neutrophil-mediated killing of bacterium [inference]

neutrophil-mediated killing of gram-negative bacterium

killing of cells of another organism [inference]

killing by host of symbiont cells [inference]

neutrophil-mediated killing of symbiont cell [inference]

neutrophil-mediated killing of bacterium [inference]

neutrophil-mediated killing of gram-negative bacterium

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

cytokine production [inference]

production of molecular mediator of immune response [inference]

cytokine production involved in immune response

cell motility [inference]

cell migration [inference]

leukocyte migration [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

myeloid leukocyte migration [inference]

granulocyte migration [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

neutrophil migration [inference]

neutrophil chemotaxis

cell chemotaxis [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

multicellular organismal process [inference]

cytokine production [inference]

locomotion [inference]

taxis [inference]

chemotaxis [inference]

cell chemotaxis [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

biological process involved in interspecies interaction between organisms [inference]

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with symbiont [inference]

killing by host of symbiont cells [inference]

neutrophil-mediated killing of symbiont cell [inference]

neutrophil-mediated killing of bacterium [inference]

neutrophil-mediated killing of gram-negative bacterium

response to other organism [inference]

defense response to other organism [inference]

innate immune response

killing by host of symbiont cells [inference]

neutrophil-mediated killing of symbiont cell [inference]

neutrophil-mediated killing of bacterium [inference]

neutrophil-mediated killing of gram-negative bacterium

disruption of anatomical structure in another organism [inference]

disruption of cell in another organism [inference]

killing of cells of another organism [inference]

killing by host of symbiont cells [inference]

neutrophil-mediated killing of symbiont cell [inference]

neutrophil-mediated killing of bacterium [inference]

neutrophil-mediated killing of gram-negative bacterium

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

innate immune response

killing by host of symbiont cells [inference]

neutrophil-mediated killing of symbiont cell [inference]

neutrophil-mediated killing of bacterium [inference]

neutrophil-mediated killing of gram-negative bacterium

immune response [inference]

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

killing by host of symbiont cells [inference]

neutrophil-mediated killing of symbiont cell [inference]

neutrophil-mediated killing of bacterium [inference]

neutrophil-mediated killing of gram-negative bacterium

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

killing by host of symbiont cells [inference]

neutrophil-mediated killing of symbiont cell [inference]

neutrophil-mediated killing of bacterium [inference]

neutrophil-mediated killing of gram-negative bacterium

Displaying 1 entry
GO Term	Evidence Code	PMID
plasma membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Triggering receptor expressed on myeloid cells 1

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
neutrophil chemotaxis
neutrophil-mediated killing of gram-negative bacterium

Displaying **all 4** entries
InterPro
Immunoglobulin V-set domain
Immunoglobulin subtype
Immunoglobulin-like domain superfamily
Immunoglobulin-like fold

Ortholog

Displaying entries **1 - 10** of 34 in total

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Species	Gene ID	Orthologous MAtrix
Homo sapiens	54210	HUMAN84708
Mus musculus	58217	MOUSE19730
Rattus norvegicus	301229	RATNO43257
Sus scrofa	396601	PIGXX31536
Canis lupus familiaris	608994	CANLF02731
Macaca mulatta	693558	MACMU34756
Callithrix jacchus	100395436	CALJA32259
Nomascus leucogenys	100587513	NOMLE12267
Papio anubis	100998592	PAPAN34202
Saimiri boliviensis boliviensis	101043821	SAIBB05448