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CXADR Ig-like cell adhesion molecule

Summary

Gene Symbol

CXADR

Organism

Pongo abelii (Sumatran orangutan)

External Links

NCBI Gene: 100174624
PubChem: 100174624

Annotation

Keyword

Cell adhesion
Cell membrane
Disulfide bond
Glycoprotein
Immunoglobulin domain
Palmitate
Phosphoprotein
Receptor
Reference proteome
Repeat
Signal
Tight junction
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q5R764

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
actin cytoskeleton organization
germ cell migration
AV node cell to bundle of His cell communication
heart development
cell-cell junction organization

GO Hierarchy

biological process

immune system process [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

T cell activation [inference]

gamma-delta T cell activation

leukocyte migration [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

myeloid leukocyte migration [inference]

granulocyte migration [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

neutrophil migration [inference]

neutrophil chemotaxis

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

T cell activation [inference]

gamma-delta T cell activation

cell communication [inference]

cell communication involved in cardiac conduction [inference]

AV node cell to bundle of His cell communication

cell adhesion [inference]

cell-cell adhesion [inference]

homotypic cell-cell adhesion

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

cellular process involved in reproduction in multicellular organism [inference]

germ cell migration

actin filament-based process [inference]

actin cytoskeleton organization

cellular developmental process [inference]

cell development [inference]

muscle cell development [inference]

cardiac muscle cell development

cardiac cell development [inference]

cardiac muscle cell development

cell motility [inference]

cell migration [inference]

germ cell migration

leukocyte migration [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

myeloid leukocyte migration [inference]

granulocyte migration [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

neutrophil migration [inference]

neutrophil chemotaxis

cell chemotaxis [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

mitochondrion organization

cytoskeleton organization [inference]

actin cytoskeleton organization

cell junction organization [inference]

cell-cell junction organization

reproductive process [inference]

cellular process involved in reproduction in multicellular organism [inference]

germ cell migration

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

T cell activation [inference]

gamma-delta T cell activation

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

epithelial structure maintenance

developmental process [inference]

anatomical structure development [inference]

cell development [inference]

muscle cell development [inference]

cardiac muscle cell development

cardiac cell development [inference]

cardiac muscle cell development

animal organ development [inference]

heart development

cellular developmental process [inference]

cell development [inference]

muscle cell development [inference]

cardiac muscle cell development

cardiac cell development [inference]

cardiac muscle cell development

locomotion [inference]

taxis [inference]

chemotaxis [inference]

cell chemotaxis [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

epithelial structure maintenance

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
apicolateral plasma membrane
plasma membrane
membrane raft
neuron projection
adherens junction

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

membrane [inference]

plasma membrane

plasma membrane region [inference]

membrane microdomain [inference]

membrane raft

cell junction [inference]

anchoring junction [inference]

cell-cell junction [inference]

adherens junction

cell-cell contact zone [inference]

intercalated disc

tight junction [inference]

bicellular tight junction

site of polarized growth [inference]

growth cone

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

actin-based cell projection [inference]

filopodium

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

intracellular membrane-bounded organelle [inference]

nucleus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

cell body

Displaying **all 4** entries
GO Term	Evidence Code	PMID
beta-catenin binding
PDZ domain binding
connexin binding
cell adhesion molecule binding	IEA	30032202

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

beta-catenin binding

protein domain specific binding [inference]

PDZ domain binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Nuclear receptor-interacting protein 1, repression domain 1

Functional Category

G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 2** entries
Gene Ontology
cell adhesion molecule binding
homotypic cell-cell adhesion

Displaying **all 6** entries
InterPro
Immunoglobulin V-set domain
Immunoglobulin subtype 2
Immunoglobulin subtype
Immunoglobulin-like domain superfamily
Immunoglobulin-like domain
Immunoglobulin-like fold

Ortholog

Displaying entries **71 - 75** of 75 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Rhinolophus ferrumequinum	117034849			RHIFE06144
Balaenoptera musculus	118894515			BALMU18492
Panthera leo	122230076			PANLE24554
Ursus americanus	123784163			URSAM07811
Pongo pygmaeus	129022438	9600_0:004f6e

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024