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4-hydroxy-2-oxoglutarate aldolase 1

Summary

Gene Symbol

HOGA1

Organism

Oryctolagus cuniculus (rabbit)

External Links

NCBI Gene: 100344505
KEGG Gene ID: ocu:100344505
PubChem: 100344505

Annotation

Keyword

Lyase
Reference proteome
Schiff base

Proteins

Displaying 1 entry
UniProt	Protein Name
G1STT8	Dihydrodipicolinate synthase-like Probable 2-keto-4-hydroxyglutarate aldolase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
N-acetylneuraminate catabolic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

organonitrogen compound metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

organonitrogen compound catabolic process [inference]

N-acetylneuraminate catabolic process

catabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

carbohydrate derivative catabolic process [inference]

amino sugar catabolic process [inference]

N-acetylneuraminate catabolic process

organonitrogen compound catabolic process [inference]

N-acetylneuraminate catabolic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

carbohydrate derivative metabolic process [inference]

amino sugar metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

amino sugar catabolic process [inference]

N-acetylneuraminate catabolic process

carbohydrate derivative catabolic process [inference]

amino sugar catabolic process [inference]

N-acetylneuraminate catabolic process

organonitrogen compound metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

organonitrogen compound catabolic process [inference]

N-acetylneuraminate catabolic process

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

carbohydrate derivative catabolic process [inference]

amino sugar catabolic process [inference]

N-acetylneuraminate catabolic process

organonitrogen compound catabolic process [inference]

N-acetylneuraminate catabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
4-hydroxy-tetrahydrodipicolinate synthase activity	IEA	30032202
N-acetylneuraminate lyase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

lyase activity [inference]

carbon-carbon lyase activity [inference]

oxo-acid-lyase activity [inference]

N-acetylneuraminate lyase activity

carbon-oxygen lyase activity [inference]

hydro-lyase activity [inference]

4-hydroxy-tetrahydrodipicolinate synthase activity

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K18123

Name

4-hydroxy-2-oxoglutarate aldolase [EC:4.1.3.16]

References

21998747

Rhea

(4R)-4-hydroxy-2-oxoglutarate

pyruvate + glyoxylate

Enzyme

4.1.3.16

PMID

5780845

(4S)-4-hydroxy-2-oxoglutarate

pyruvate + glyoxylate

Enzyme

PMID

Ortholog

Displaying entries **31 - 40** of 91 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Gorilla gorilla gorilla	101123681		GORGO00573
Gorilla gorilla gorilla	101154009		GORGO00573
Pan troglodytes	450656		PANTR01298
Pan troglodytes	742884		PANTR01298
Pongo abelii	100171598		PONAB01172
Homo sapiens	112817		HUMAN02417
Canis lupus familiaris	608755		CANLF11357
Vulpes vulpes	112914409		VULVU00707
Ursus americanus	123783886		URSAM06757
Ailuropoda melanoleuca	100478059		AILME15095

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

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Last updated: August 19, 2024