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cadherin 6

Summary

Gene Symbol

CDH6

Organism

Homo sapiens (human)

External Links

NCBI Gene

1004

PubChem

1004

Alliance of Genome Resources

HGNC:1765

Annotation

Keyword

3D-structure
Alternative splicing
Calcium
Cell adhesion
Cell membrane
Cleavage on pair of basic residues
Glycoprotein
Metal-binding
Phosphoprotein
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P55285	Kidney cadherin

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
cell morphogenesis	IBA
adherens junction organization	IBA
cell-cell adhesion mediated by cadherin	IBA
Notch signaling pathway	IEA
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	IBA

GO Hierarchy

biological process

cellular process [inference]

cell adhesion

cell-cell adhesion [inference]

cell-cell adhesion mediated by cadherin

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Notch signaling pathway

cell motility [inference]

cell migration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

cell junction assembly [inference]

cell-cell junction assembly

cell junction organization [inference]

cell junction assembly [inference]

cell-cell junction assembly

cell-cell junction organization [inference]

developmental process [inference]

anatomical structure morphogenesis [inference]

cell morphogenesis

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Notch signaling pathway

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GO Term	Evidence Code	PMID
cell junction	IDA
plasma membrane	IDA TAS
adherens junction	IBA
nucleoplasm	IDA
catenin complex	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

catenin complex

cellular anatomical entity [inference]

nucleoplasm

membrane [inference]

plasma membrane

cell junction

synapse [inference]

glutamatergic synapse

anchoring junction [inference]

cell-cell junction [inference]

adherens junction

Displaying **all 3** entries
GO Term	Evidence Code	PMID
beta-catenin binding	IBA
calcium ion binding	IEA
cadherin binding	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

beta-catenin binding

cell adhesion molecule binding [inference]

cadherin binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Cadherin

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis

Displaying **all 2** entries
Gene Ontology
calcium ion binding
homophilic cell adhesion via plasma membrane adhesion molecules

Displaying **all 3** entries
InterPro
Cadherin conserved site
Cadherin-like superfamily
Cadherin-like

Ortholog

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	12563		MGI:107435	MOUSE15562
Rattus norvegicus	25409		RGD:2322	RATNO24520
Xenopus laevis	373627		Xenbase:XB-GENE-865103
Pan troglodytes	461937	9598_0:0018ec		PANTR35791
Bos taurus	537946			BOVIN16112
Danio rerio	541393		ZFIN:ZDB-GENE-050320-92
Macaca mulatta	695557			MACMU38689
Monodelphis domestica	100016010			MONDO18466
Equus caballus	100068795			HORSE20482
Ornithorhynchus anatinus	100078953			ORNAN30862