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cytochrome P450, family 3, subfamily A, polypeptide 4

Summary

Gene Symbol

CYP3A4

Organism

Callithrix jacchus (white-tufted-ear marmoset)

External Links

NCBI Gene: 100404344
KEGG Gene ID: cjc:100404344
PubChem: 100404344

Annotation

Keyword

Heme
Membrane
Microsome
Monooxygenase
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
O18993	CYPIIIA21 Cytochrome P450 CM3A-10

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
steroid metabolic process	IEA	30032202
oxidative demethylation	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process

demethylation [inference]

oxidative demethylation

organic substance metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process

organic cyclic compound metabolic process [inference]

steroid metabolic process

Displaying **all 5** entries
GO Term	Evidence Code	PMID
iron ion binding	IEA	22301074
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	IEA	22301074
heme binding	IEA	22301074
estrogen 16-alpha-hydroxylase activity	IEA	30032202
testosterone 6-beta-hydroxylase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

monooxygenase activity [inference]

steroid hydroxylase activity [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [inference]

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

iron ion binding

organic cyclic compound binding [inference]

tetrapyrrole binding [inference]

heme binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K17689

Name

cytochrome P450 family 3 subfamily A4 [EC:1.14.13.32 1.14.14.55 1.14.14.56 1.14.14.57 1.14.14.73 1.14.14.-]

References

Rhea

an organic molecule + O₂

H₂O + H⁺ + an alcohol

Enzyme

1.14.14.1

PMID

Ortholog

Displaying entries **121 - 125** of **125** in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Propithecus coquereli	105806022		PROCO08992
Propithecus coquereli	105806023		PROCO08994
Corvus moneduloides	116452187		CORMO04840
Carlito syrichta	103252931		CARSF27473
Cebus imitator	108308036		CEBIM08601

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.0.0

Last updated: August 19, 2024