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mannosidase alpha class 1A member 1

Summary

Gene Symbol

MAN1A1

Organism

Pongo abelii (Sumatran orangutan)

External Links

NCBI Gene: 100434522
KEGG Gene ID: pon:100434522
PubChem: 100434522

Annotation

Keyword

Calcium
Disulfide bond
Glycosidase
Metal-binding
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
H2PK77

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
carbohydrate metabolic process	IEA	22301074
mannose trimming involved in glycoprotein ERAD pathway	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

protein deglycosylation [inference]

protein deglycosylation involved in glycoprotein catabolic process [inference]

mannose trimming involved in glycoprotein ERAD pathway

protein demannosylation [inference]

protein alpha-1,2-demannosylation [inference]

mannose trimming involved in glycoprotein ERAD pathway

protein modification process [inference]

protein deglycosylation [inference]

protein deglycosylation involved in glycoprotein catabolic process [inference]

mannose trimming involved in glycoprotein ERAD pathway

protein demannosylation [inference]

protein alpha-1,2-demannosylation [inference]

mannose trimming involved in glycoprotein ERAD pathway

primary metabolic process [inference]

carbohydrate metabolic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

protein deglycosylation [inference]

protein deglycosylation involved in glycoprotein catabolic process [inference]

mannose trimming involved in glycoprotein ERAD pathway

protein demannosylation [inference]

protein alpha-1,2-demannosylation [inference]

mannose trimming involved in glycoprotein ERAD pathway

protein modification process [inference]

protein deglycosylation [inference]

protein deglycosylation involved in glycoprotein catabolic process [inference]

mannose trimming involved in glycoprotein ERAD pathway

protein demannosylation [inference]

protein alpha-1,2-demannosylation [inference]

mannose trimming involved in glycoprotein ERAD pathway

organic substance metabolic process [inference]

carbohydrate metabolic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

protein deglycosylation [inference]

protein deglycosylation involved in glycoprotein catabolic process [inference]

mannose trimming involved in glycoprotein ERAD pathway

protein demannosylation [inference]

protein alpha-1,2-demannosylation [inference]

mannose trimming involved in glycoprotein ERAD pathway

protein modification process [inference]

protein deglycosylation [inference]

protein deglycosylation involved in glycoprotein catabolic process [inference]

mannose trimming involved in glycoprotein ERAD pathway

protein demannosylation [inference]

protein alpha-1,2-demannosylation [inference]

mannose trimming involved in glycoprotein ERAD pathway

macromolecule modification [inference]

protein modification process [inference]

protein deglycosylation [inference]

protein deglycosylation involved in glycoprotein catabolic process [inference]

mannose trimming involved in glycoprotein ERAD pathway

protein demannosylation [inference]

protein alpha-1,2-demannosylation [inference]

mannose trimming involved in glycoprotein ERAD pathway

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process [inference]

protein deglycosylation [inference]

protein deglycosylation involved in glycoprotein catabolic process [inference]

mannose trimming involved in glycoprotein ERAD pathway

protein demannosylation [inference]

protein alpha-1,2-demannosylation [inference]

mannose trimming involved in glycoprotein ERAD pathway

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

protein deglycosylation [inference]

protein deglycosylation involved in glycoprotein catabolic process [inference]

mannose trimming involved in glycoprotein ERAD pathway

protein demannosylation [inference]

protein alpha-1,2-demannosylation [inference]

mannose trimming involved in glycoprotein ERAD pathway

protein modification process [inference]

protein deglycosylation [inference]

protein deglycosylation involved in glycoprotein catabolic process [inference]

mannose trimming involved in glycoprotein ERAD pathway

protein demannosylation [inference]

protein alpha-1,2-demannosylation [inference]

mannose trimming involved in glycoprotein ERAD pathway

Displaying **all 3** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum	IEA	30032202
Golgi membrane	IEA	30032202
extracellular exosome	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying **all 2** entries
GO Term	Evidence Code	PMID
mannosyl-oligosaccharide 1,2-alpha-mannosidase activity	IEA	22301074 30032202
calcium ion binding	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing O-glycosyl compounds [inference]

mannosidase activity [inference]

alpha-mannosidase activity [inference]

mannosyl-oligosaccharide mannosidase activity [inference]

mannosyl-oligosaccharide 1,2-alpha-mannosidase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K01230

Name

mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]

References

Reactions

Displaying 1 entry
KEGG Reaction	Enzyme	Acceptor	Product
R12479	3.2.1.113	G40702WU	G55220VL

Ortholog

Displaying entries **41 - 50** of 70 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Anolis carolinensis	100552898		ANOCA01323
Cyprinodon variegatus	107083523		CYPVA05780
Vombatus ursinus	114033194		VOMUR14715
Bos indicus x Bos taurus	113898185		BOBOX27852
Otolemur garnettii	100940869		OTOGA18672
Neolamprologus brichardi	102782693		NEOBR26111
Kryptolebias marmoratus	108244885		KRYMA21165
Aotus nancymaae	105715664		AOTNA23445
Phascolarctos cinereus	110197597		PHACI10559
Saimiri boliviensis boliviensis	101039212		SAIBB30366

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GlyCosmos Portal v4.0.0

Last updated: August 19, 2024