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glucosylceramidase beta 2

Summary

Gene Symbol

GBA2

Organism

Pongo abelii (Sumatran orangutan)

External Links

NCBI Gene: 100438148
KEGG Gene ID: pon:100438148
PubChem: 100438148

Annotation

Keyword

Endoplasmic reticulum
Glycosidase
Golgi apparatus
Lipid metabolism
Membrane
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A6D2W4Q2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
carbohydrate metabolic process	IEA	22301074
glucosylceramide catabolic process	IEA	22301074
central nervous system development	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

organonitrogen compound catabolic process [inference]

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

catabolic process [inference]

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

carbohydrate derivative catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

organonitrogen compound catabolic process [inference]

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

cellular metabolic process [inference]

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

primary metabolic process [inference]

carbohydrate metabolic process

lipid metabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process

lipid metabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

carbohydrate derivative metabolic process [inference]

carbohydrate derivative catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

organonitrogen compound catabolic process [inference]

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

carbohydrate derivative catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

organonitrogen compound catabolic process [inference]

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

developmental process [inference]

anatomical structure development [inference]

system development [inference]

central nervous system development

Displaying 1 entry
GO Term	Evidence Code	PMID
membrane	IEA	22301074

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
glucosylceramidase activity	IEA	22301074
beta-glucosidase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing O-glycosyl compounds [inference]

glucosylceramidase activity

glucosidase activity [inference]

beta-glucosidase activity

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K17108

Name

non-lysosomal glucosylceramidase [EC:3.2.1.45]

References

Rhea

H₂O + a β-D-glucosyl-(1↔1ʼ)-N-acylsphing-4-enine

D-glucose + an N-acylsphing-4-enine

Enzyme

3.2.1.45

PMID

Ortholog

Displaying entries **71 - 80** of 88 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Rhinopithecus bieti	108518992		RHIBE38884
Rhinopithecus roxellana	104672453		RHIRO38714
Nomascus leucogenys	100598447		NOMLE35404
Podarcis muralis	114606917		PODMU10668
Sinocyclocheilus grahami	107588172		SINGR42586
Amphiprion ocellaris	111580210		AMPOC18404
Equus asinus asinus	106846979		EQUAS27765
Chelonoidis abingdonii	116816742		CHEAB28458
Hippocampus comes	109508388		HIPCM08296
Pteropus vampyrus	105306464		PTEVA03986

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Acknowledgements

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Last updated: August 19, 2024