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alkaline ceramidase 3

Summary

Gene Symbol

ACER3

Organism

Pan paniscus (pygmy chimpanzee)

External Links

NCBI Gene: 100977059
KEGG Gene ID: pps:100977059
PubChem: 100977059

Annotation

Keyword

Hydrolase
Lipid metabolism
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A2R8ZFR3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
ceramide metabolic process	IEA	22301074 30032202
phytosphingosine biosynthetic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

phytosphingosine biosynthetic process

amide metabolic process [inference]

ceramide metabolic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

sphingolipid biosynthetic process [inference]

sphingoid biosynthetic process [inference]

phytosphingosine biosynthetic process

sphingoid metabolic process [inference]

phytosphingosine metabolic process [inference]

phytosphingosine biosynthetic process

sphingoid biosynthetic process [inference]

phytosphingosine biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

sphingoid biosynthetic process [inference]

phytosphingosine biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

phytosphingosine biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

sphingoid biosynthetic process [inference]

phytosphingosine biosynthetic process

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

phytosphingosine biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

sphingoid biosynthetic process [inference]

phytosphingosine biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

sphingoid biosynthetic process [inference]

phytosphingosine biosynthetic process

organic hydroxy compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

phytosphingosine biosynthetic process

cellular metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

phytosphingosine biosynthetic process

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

phytosphingosine biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

sphingoid biosynthetic process [inference]

phytosphingosine biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

sphingolipid biosynthetic process [inference]

sphingoid biosynthetic process [inference]

phytosphingosine biosynthetic process

sphingoid metabolic process [inference]

phytosphingosine metabolic process [inference]

phytosphingosine biosynthetic process

sphingoid biosynthetic process [inference]

phytosphingosine biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

sphingoid biosynthetic process [inference]

phytosphingosine biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

sphingoid biosynthetic process [inference]

phytosphingosine biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

sphingolipid biosynthetic process [inference]

sphingoid biosynthetic process [inference]

phytosphingosine biosynthetic process

sphingoid metabolic process [inference]

phytosphingosine metabolic process [inference]

phytosphingosine biosynthetic process

sphingoid biosynthetic process [inference]

phytosphingosine biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

sphingoid biosynthetic process [inference]

phytosphingosine biosynthetic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

phytosphingosine metabolic process [inference]

phytosphingosine biosynthetic process

polyol biosynthetic process [inference]

phytosphingosine biosynthetic process

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

phytosphingosine biosynthetic process

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

phytosphingosine biosynthetic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

sphingoid biosynthetic process [inference]

phytosphingosine biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

sphingolipid biosynthetic process [inference]

sphingoid biosynthetic process [inference]

phytosphingosine biosynthetic process

sphingoid metabolic process [inference]

phytosphingosine metabolic process [inference]

phytosphingosine biosynthetic process

sphingoid biosynthetic process [inference]

phytosphingosine biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

sphingoid biosynthetic process [inference]

phytosphingosine biosynthetic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

sphingolipid biosynthetic process [inference]

sphingoid biosynthetic process [inference]

phytosphingosine biosynthetic process

sphingoid metabolic process [inference]

phytosphingosine metabolic process [inference]

phytosphingosine biosynthetic process

sphingoid biosynthetic process [inference]

phytosphingosine biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

sphingoid biosynthetic process [inference]

phytosphingosine biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

sphingoid biosynthetic process [inference]

phytosphingosine biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

sphingoid biosynthetic process [inference]

phytosphingosine biosynthetic process

organic hydroxy compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

phytosphingosine biosynthetic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

phytosphingosine metabolic process [inference]

phytosphingosine biosynthetic process

polyol biosynthetic process [inference]

phytosphingosine biosynthetic process

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

phytosphingosine biosynthetic process

organic hydroxy compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

phytosphingosine biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

phytosphingosine biosynthetic process

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

phytosphingosine biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

sphingoid biosynthetic process [inference]

phytosphingosine biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

sphingolipid biosynthetic process [inference]

sphingoid biosynthetic process [inference]

phytosphingosine biosynthetic process

sphingoid metabolic process [inference]

phytosphingosine metabolic process [inference]

phytosphingosine biosynthetic process

sphingoid biosynthetic process [inference]

phytosphingosine biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

sphingoid biosynthetic process [inference]

phytosphingosine biosynthetic process

Displaying 1 entry
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

Displaying 1 entry
GO Term	Evidence Code	PMID
phytoceramidase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing O-glycosyl compounds [inference]

phytoceramidase activity

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [inference]

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [inference]

N-acylsphingosine amidohydrolase activity [inference]

phytoceramidase activity

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K04711

Name

dihydroceramidase [EC:3.5.1.-]

References

11356846

Ortholog

Displaying entries **1 - 10** of 62 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Danio rerio	555411		DANRE00351
Astyanax mexicanus	103042148		ASTMX02985
Ictalurus punctatus	108276919		ICTPU09481
Electrophorus electricus	113580729		ELEEL26978
Salmo salar	106567925		SALSA28726
Salmo salar	106603557		SALSA121232
Salmo trutta	115148915		SALTR20485
Salmo trutta	115154373		SALTR103673
Gadus morhua	115547828		GADMO54642
Oreochromis niloticus	100710861		ORENI03093

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024