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sterol-C5-desaturase

Summary

Gene Symbol

SC5D

Organism

Pan paniscus (pygmy chimpanzee)

External Links

NCBI Gene: 100979606
KEGG Gene ID: pps:100979606
PubChem: 100979606

Annotation

Keyword

Endoplasmic reticulum
Reference proteome
Sterol biosynthesis
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A2R9CLH4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
cholesterol biosynthetic process via lathosterol	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

small molecule metabolic process [inference]

alcohol metabolic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

secondary alcohol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

organic substance metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

secondary alcohol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

Displaying 1 entry
GO Term	Evidence Code	PMID
membrane	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
C-5 sterol desaturase activity	IEA	30032202
iron ion binding	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [inference]

oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [inference]

C-5 sterol desaturase activity

sterol desaturase activity [inference]

C-5 sterol desaturase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

iron ion binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00227

Name

Delta7-sterol 5-desaturase [EC:1.14.19.20]

References

Ortholog

Displaying entries **11 - 20** of 86 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Oryzias latipes	101173647		ORYLA04549
Oreochromis niloticus	100695064		ORENI04892
Sparus aurata	115594615		SPAAU20397
Chrysemys picta bellii	101952975		CHRPI14699
Crocodylus porosus	109318043		CROPO23308
Pseudonaja textilis	113441958		PSETE14107
Serinus canaria	103823051		SERCA19941
Ornithorhynchus anatinus	100073392		ORNAN03178
Sarcophilus harrisii	100932949		SARHA02190
Sarcophilus harrisii	116419258		SARHA02190

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024