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glucose-6-phosphate dehydrogenase

Summary

Gene Symbol

G6PD

Organism

Pan paniscus (pygmy chimpanzee)

External Links

NCBI Gene: 100985592
KEGG Gene ID: pps:100985592
PubChem: 100985592

Annotation

Keyword

Glucose metabolism
NADP
Oxidoreductase
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A2R9A9Q3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
glucose metabolic process	IEA	22301074 30032202
pentose-phosphate shunt, oxidative branch	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

organonitrogen compound metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

glucose 6-phosphate metabolic process [inference]

pentose-phosphate shunt, oxidative branch

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

glucose 6-phosphate metabolic process [inference]

pentose-phosphate shunt, oxidative branch

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

glucose 6-phosphate metabolic process [inference]

pentose-phosphate shunt, oxidative branch

carbohydrate derivative metabolic process [inference]

glucose 6-phosphate metabolic process [inference]

pentose-phosphate shunt, oxidative branch

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

organonitrogen compound metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

cellular process [inference]

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

glucose 6-phosphate metabolic process [inference]

pentose-phosphate shunt, oxidative branch

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

glucose 6-phosphate metabolic process [inference]

pentose-phosphate shunt, oxidative branch

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt, oxidative branch

Displaying 1 entry
GO Term	Evidence Code	PMID
cytosol	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

Displaying **all 2** entries
GO Term	Evidence Code	PMID
glucose-6-phosphate dehydrogenase activity	IEA	22301074 30032202
NADP binding	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

glucose-6-phosphate dehydrogenase activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NADP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NADP binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00036

Name

glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]

References

Rhea

NADP⁺ + D-glucose 6-phosphate

H⁺ + NADPH + 6-phospho-D-glucono-1,5-lactone

Enzyme

PMID

Ortholog

Displaying entries **11 - 20** of 73 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Poecilia reticulata	103467627		POERE30340
Oryzias latipes	101158357		ORYLA15973
Haplochromis burtoni	102300702		HAPBU11524
Sparus aurata	115584342		SPAAU52128
Chrysemys picta bellii	101939850		CHRPI26841
Pseudonaja textilis	113443419		PSETE15740
Ornithorhynchus anatinus	100073461		ORNAN23587
Callithrix jacchus	100388810		CALJA48297
Cercocebus atys	105579745		CERAT45795
Macaca fascicularis	102117021		MACFA45489

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Last updated: August 19, 2024