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killer cell lectin like receptor D1

Summary

Gene Symbol

KLRD1

Organism

Pan paniscus (pygmy chimpanzee)

External Links

NCBI Gene: 100992162
KEGG Gene ID: pps:100992162
PubChem: 100992162

Annotation

Keyword

Receptor
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A2R9C883	Killer cell lectin-like receptor subfamily D member 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
stimulatory C-type lectin receptor signaling pathway	IEA	30032202
positive regulation of natural killer cell mediated cytotoxicity	IEA	30032202

GO Hierarchy

biological process

immune system process [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

cell surface receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

response to stimulus [inference]

response to biotic stimulus [inference]

response to lectin [inference]

cellular response to lectin [inference]

stimulatory C-type lectin receptor signaling pathway

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of immune effector process [inference]

positive regulation of leukocyte mediated immunity [inference]

positive regulation of leukocyte mediated cytotoxicity [inference]

positive regulation of natural killer cell mediated cytotoxicity

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of natural killer cell mediated immunity [inference]

positive regulation of natural killer cell mediated cytotoxicity

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

positive regulation of natural killer cell mediated immunity [inference]

positive regulation of natural killer cell mediated cytotoxicity

regulation of immune effector process [inference]

positive regulation of immune effector process [inference]

positive regulation of leukocyte mediated immunity [inference]

positive regulation of leukocyte mediated cytotoxicity [inference]

positive regulation of natural killer cell mediated cytotoxicity

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of natural killer cell mediated immunity [inference]

positive regulation of natural killer cell mediated cytotoxicity

regulation of leukocyte mediated immunity [inference]

regulation of leukocyte mediated cytotoxicity [inference]

positive regulation of leukocyte mediated cytotoxicity [inference]

positive regulation of natural killer cell mediated cytotoxicity

regulation of natural killer cell mediated cytotoxicity [inference]

positive regulation of natural killer cell mediated cytotoxicity

positive regulation of leukocyte mediated immunity [inference]

positive regulation of leukocyte mediated cytotoxicity [inference]

positive regulation of natural killer cell mediated cytotoxicity

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of natural killer cell mediated immunity [inference]

positive regulation of natural killer cell mediated cytotoxicity

regulation of lymphocyte mediated immunity [inference]

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of natural killer cell mediated immunity [inference]

positive regulation of natural killer cell mediated cytotoxicity

regulation of natural killer cell mediated immunity [inference]

positive regulation of natural killer cell mediated immunity [inference]

positive regulation of natural killer cell mediated cytotoxicity

regulation of natural killer cell mediated cytotoxicity [inference]

positive regulation of natural killer cell mediated cytotoxicity

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

regulation of innate immune response [inference]

regulation of natural killer cell mediated immunity [inference]

positive regulation of natural killer cell mediated immunity [inference]

positive regulation of natural killer cell mediated cytotoxicity

regulation of natural killer cell mediated cytotoxicity [inference]

positive regulation of natural killer cell mediated cytotoxicity

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

positive regulation of natural killer cell mediated immunity [inference]

positive regulation of natural killer cell mediated cytotoxicity

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

positive regulation of natural killer cell mediated immunity [inference]

positive regulation of natural killer cell mediated cytotoxicity

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune effector process [inference]

positive regulation of leukocyte mediated immunity [inference]

positive regulation of leukocyte mediated cytotoxicity [inference]

positive regulation of natural killer cell mediated cytotoxicity

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of natural killer cell mediated immunity [inference]

positive regulation of natural killer cell mediated cytotoxicity

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

positive regulation of natural killer cell mediated immunity [inference]

positive regulation of natural killer cell mediated cytotoxicity

positive regulation of cellular process [inference]

positive regulation of cell killing [inference]

positive regulation of leukocyte mediated cytotoxicity [inference]

positive regulation of natural killer cell mediated cytotoxicity

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

positive regulation of natural killer cell mediated immunity [inference]

positive regulation of natural killer cell mediated cytotoxicity

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

positive regulation of natural killer cell mediated immunity [inference]

positive regulation of natural killer cell mediated cytotoxicity

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

positive regulation of natural killer cell mediated immunity [inference]

positive regulation of natural killer cell mediated cytotoxicity

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

positive regulation of natural killer cell mediated immunity [inference]

positive regulation of natural killer cell mediated cytotoxicity

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

positive regulation of natural killer cell mediated immunity [inference]

positive regulation of natural killer cell mediated cytotoxicity

regulation of innate immune response [inference]

regulation of natural killer cell mediated immunity [inference]

positive regulation of natural killer cell mediated immunity [inference]

positive regulation of natural killer cell mediated cytotoxicity

regulation of natural killer cell mediated cytotoxicity [inference]

positive regulation of natural killer cell mediated cytotoxicity

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

positive regulation of natural killer cell mediated immunity [inference]

positive regulation of natural killer cell mediated cytotoxicity

regulation of response to external stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

positive regulation of natural killer cell mediated immunity [inference]

positive regulation of natural killer cell mediated cytotoxicity

regulation of innate immune response [inference]

regulation of natural killer cell mediated immunity [inference]

positive regulation of natural killer cell mediated immunity [inference]

positive regulation of natural killer cell mediated cytotoxicity

regulation of natural killer cell mediated cytotoxicity [inference]

positive regulation of natural killer cell mediated cytotoxicity

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

positive regulation of natural killer cell mediated immunity [inference]

positive regulation of natural killer cell mediated cytotoxicity

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

positive regulation of natural killer cell mediated immunity [inference]

positive regulation of natural killer cell mediated cytotoxicity

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

positive regulation of natural killer cell mediated immunity [inference]

positive regulation of natural killer cell mediated cytotoxicity

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

positive regulation of natural killer cell mediated immunity [inference]

positive regulation of natural killer cell mediated cytotoxicity

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

positive regulation of natural killer cell mediated immunity [inference]

positive regulation of natural killer cell mediated cytotoxicity

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

regulation of innate immune response [inference]

regulation of natural killer cell mediated immunity [inference]

positive regulation of natural killer cell mediated immunity [inference]

positive regulation of natural killer cell mediated cytotoxicity

regulation of natural killer cell mediated cytotoxicity [inference]

positive regulation of natural killer cell mediated cytotoxicity

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

positive regulation of natural killer cell mediated immunity [inference]

positive regulation of natural killer cell mediated cytotoxicity

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

positive regulation of natural killer cell mediated immunity [inference]

positive regulation of natural killer cell mediated cytotoxicity

regulation of response to stress [inference]

regulation of defense response [inference]

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

positive regulation of natural killer cell mediated immunity [inference]

positive regulation of natural killer cell mediated cytotoxicity

regulation of innate immune response [inference]

regulation of natural killer cell mediated immunity [inference]

positive regulation of natural killer cell mediated immunity [inference]

positive regulation of natural killer cell mediated cytotoxicity

regulation of natural killer cell mediated cytotoxicity [inference]

positive regulation of natural killer cell mediated cytotoxicity

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

positive regulation of natural killer cell mediated immunity [inference]

positive regulation of natural killer cell mediated cytotoxicity

regulation of cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

cell surface receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

regulation of cell killing [inference]

regulation of leukocyte mediated cytotoxicity [inference]

positive regulation of leukocyte mediated cytotoxicity [inference]

positive regulation of natural killer cell mediated cytotoxicity

regulation of natural killer cell mediated cytotoxicity [inference]

positive regulation of natural killer cell mediated cytotoxicity

positive regulation of cell killing [inference]

positive regulation of leukocyte mediated cytotoxicity [inference]

positive regulation of natural killer cell mediated cytotoxicity

positive regulation of cellular process [inference]

positive regulation of cell killing [inference]

positive regulation of leukocyte mediated cytotoxicity [inference]

positive regulation of natural killer cell mediated cytotoxicity

Displaying **all 2** entries
GO Term	Evidence Code	PMID
external side of plasma membrane	IEA	30032202
plasma membrane	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

side of membrane [inference]

external side of plasma membrane

Displaying 1 entry
GO Term	Evidence Code	PMID
transmembrane signaling receptor activity	IEA	30032202

GO Hierarchy

molecular function

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Hominidae

Group Name

C-type lectin-like

Functional Category

C: Energy production and conversion
J: Translation, ribosomal structure and biogenesis
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying entries **1 - 10** of 13 in total

1

2

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Last »
Gene Ontology
HLA-E specific inhibitory MHC class Ib receptor activity
MHC class I protein complex binding
MHC class Ib protein binding, via antigen binding groove
adaptive immune response
cell surface receptor signaling pathway
immune system process
natural killer cell mediated immunity
negative regulation of T cell mediated cytotoxicity
negative regulation of natural killer cell mediated cytotoxicity
positive regulation of natural killer cell mediated cytotoxicity

KEGG BRITE Database

Orthology

K06516

Name

killer cell lectin-like receptor subfamily D member 1

References

Ortholog

Displaying entries **31 - 37** of 37 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Rhinopithecus bieti	108542154			RHIBE35635
Bos indicus x Bos taurus	113892460			BOBOX39986
Ornithorhynchus anatinus	114817875			ORNAN08811
Tursiops truncatus	117314288			TURTR01122
Balaenoptera musculus	118901755			BALMU03202
Panthera leo	122225561			PANLE16460
Pongo pygmaeus	129009764	9600_0:00347d

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Last updated: December 9, 2024