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Guidelines

MIRAGE

homeodomain interacting protein kinase 3

Summary

Gene Symbol

HIPK3

Organism

Homo sapiens (human)

External Links

NCBI Gene

10114

PubChem

10114

Alliance of Genome Resources

HGNC:4915

JoGo

HIPK3

TogoVar

HIPK3

Annotation

Keyword

3D-structure
ATP-binding
Alternative splicing
Apoptosis
Cytoplasm
Isopeptide bond
Nucleus
Phosphoprotein
Proteomics identification
Reference proteome
Serine/threonine-protein kinase
Transcription regulation
Ubl conjugation

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A8KAE4
Q9H422	Androgen receptor-interacting nuclear protein kinase Fas-interacting serine/threonine-protein kinase Homolog of protein kinase YAK1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

1

2

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Last »
GO Term	Evidence Code	PMID
chromatin remodeling	IEA
protein phosphorylation	IDA	14766760
apoptotic process	IEA
mRNA transcription	IDA	17210646
peptidyl-serine phosphorylation	ISS	11034606

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mRNA metabolic process [inference]

mRNA transcription

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

peptidyl-serine phosphorylation

peptidyl-threonine modification [inference]

peptidyl-threonine phosphorylation

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mRNA metabolic process [inference]

mRNA transcription

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mRNA metabolic process [inference]

mRNA transcription

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mRNA metabolic process [inference]

mRNA transcription

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mRNA metabolic process [inference]

mRNA transcription

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

peptidyl-serine phosphorylation

peptidyl-threonine modification [inference]

peptidyl-threonine phosphorylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

peptidyl-serine phosphorylation

peptidyl-threonine modification [inference]

peptidyl-threonine phosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein phosphorylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

peptidyl-serine phosphorylation

peptidyl-threonine modification [inference]

peptidyl-threonine phosphorylation

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mRNA metabolic process [inference]

mRNA transcription

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mRNA metabolic process [inference]

mRNA transcription

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

peptidyl-serine phosphorylation

peptidyl-threonine modification [inference]

peptidyl-threonine phosphorylation

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

cellular process [inference]

cell death [inference]

programmed cell death [inference]

apoptotic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mRNA metabolic process [inference]

mRNA transcription

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mRNA metabolic process [inference]

mRNA transcription

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mRNA metabolic process [inference]

mRNA transcription

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

mRNA transcription

cellular component organization or biogenesis [inference]

cellular component organization [inference]

protein-containing complex organization [inference]

protein-DNA complex organization [inference]

chromatin organization [inference]

chromatin remodeling

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of phosphorus metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of JUN kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of kinase activity [inference]

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of JUN kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of nitrogen compound metabolic process [inference]

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of JUN kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of JUN kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of JUN kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of stress-activated MAPK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of stress-activated protein kinase signaling cascade [inference]

negative regulation of stress-activated MAPK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

regulation of stress-activated MAPK cascade [inference]

negative regulation of stress-activated MAPK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

regulation of JNK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

negative regulation of MAPK cascade [inference]

negative regulation of stress-activated MAPK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of stress-activated protein kinase signaling cascade [inference]

regulation of stress-activated MAPK cascade [inference]

negative regulation of stress-activated MAPK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

regulation of JNK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

negative regulation of stress-activated protein kinase signaling cascade [inference]

negative regulation of stress-activated MAPK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of stress-activated MAPK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of stress-activated protein kinase signaling cascade [inference]

negative regulation of stress-activated MAPK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of stress-activated MAPK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of stress-activated protein kinase signaling cascade [inference]

negative regulation of stress-activated MAPK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of stress-activated MAPK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of stress-activated protein kinase signaling cascade [inference]

negative regulation of stress-activated MAPK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of stress-activated MAPK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of stress-activated protein kinase signaling cascade [inference]

negative regulation of stress-activated MAPK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of stress-activated MAPK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of stress-activated protein kinase signaling cascade [inference]

negative regulation of stress-activated MAPK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of stress-activated MAPK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of stress-activated protein kinase signaling cascade [inference]

negative regulation of stress-activated MAPK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

regulation of stress-activated MAPK cascade [inference]

negative regulation of stress-activated MAPK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

regulation of JNK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

negative regulation of MAPK cascade [inference]

negative regulation of stress-activated MAPK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of stress-activated protein kinase signaling cascade [inference]

regulation of stress-activated MAPK cascade [inference]

negative regulation of stress-activated MAPK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

regulation of JNK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

negative regulation of stress-activated protein kinase signaling cascade [inference]

negative regulation of stress-activated MAPK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of stress-activated MAPK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of stress-activated protein kinase signaling cascade [inference]

negative regulation of stress-activated MAPK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of stress-activated MAPK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of stress-activated protein kinase signaling cascade [inference]

negative regulation of stress-activated MAPK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

regulation of response to stress [inference]

regulation of cellular response to stress [inference]

regulation of stress-activated protein kinase signaling cascade [inference]

regulation of stress-activated MAPK cascade [inference]

negative regulation of stress-activated MAPK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

regulation of JNK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

negative regulation of stress-activated protein kinase signaling cascade [inference]

negative regulation of stress-activated MAPK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of stress-activated MAPK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of stress-activated protein kinase signaling cascade [inference]

negative regulation of stress-activated MAPK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

regulation of stress-activated MAPK cascade [inference]

negative regulation of stress-activated MAPK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

regulation of JNK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

negative regulation of MAPK cascade [inference]

negative regulation of stress-activated MAPK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of stress-activated protein kinase signaling cascade [inference]

regulation of stress-activated MAPK cascade [inference]

negative regulation of stress-activated MAPK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

regulation of JNK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

negative regulation of stress-activated protein kinase signaling cascade [inference]

negative regulation of stress-activated MAPK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of stress-activated MAPK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of stress-activated protein kinase signaling cascade [inference]

negative regulation of stress-activated MAPK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of stress-activated MAPK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of stress-activated protein kinase signaling cascade [inference]

negative regulation of stress-activated MAPK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of phosphorus metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of JUN kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of kinase activity [inference]

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of JUN kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of stress-activated MAPK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of stress-activated protein kinase signaling cascade [inference]

negative regulation of stress-activated MAPK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

regulation of cellular response to stress [inference]

regulation of stress-activated protein kinase signaling cascade [inference]

regulation of stress-activated MAPK cascade [inference]

negative regulation of stress-activated MAPK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

regulation of JNK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

negative regulation of stress-activated protein kinase signaling cascade [inference]

negative regulation of stress-activated MAPK cascade [inference]

negative regulation of JNK cascade [inference]

negative regulation of JUN kinase activity

regulation of molecular function [inference]

negative regulation of molecular function [inference]

negative regulation of catalytic activity [inference]

negative regulation of transferase activity [inference]

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of catalytic activity [inference]

negative regulation of catalytic activity [inference]

negative regulation of transferase activity [inference]

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of transferase activity [inference]

regulation of kinase activity [inference]

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

regulation of JUN kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

negative regulation of transferase activity [inference]

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity [inference]

negative regulation of JUN kinase activity

Displaying entries **1 - 5** of 6 in total

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2

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GO Term	Evidence Code	PMID
nucleus	IBA
cytoplasm	IBA
cytosol	IDA
plasma membrane	IDA
nuclear body	IDA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

PML body

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying entries **1 - 5** of 27 in total

1

2

3

4

5

6

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GO Term	Evidence Code	PMID
protein kinase activity	IDA	14766760
protein serine/threonine kinase activity	ISS	11034606
protein serine/threonine kinase activity	IDA	10919273
protein serine/threonine kinase activity	IBA
3-phosphoinositide-dependent protein kinase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity

protein serine/threonine kinase activity

protein tyrosine kinase activity

histone kinase activity [inference]

histone H2A kinase activity [inference]

histone H3 kinase activity [inference]

histone H4 kinase activity [inference]

histone H4S1 kinase activity

histone H2B kinase activity [inference]

histone H2AX kinase activity [inference]

histone H2AXS139 kinase activity

protein serine kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity

protein serine/threonine kinase activity

protein tyrosine kinase activity

histone kinase activity [inference]

histone H2A kinase activity [inference]

histone H3 kinase activity [inference]

histone H4 kinase activity [inference]

histone H4S1 kinase activity

histone H2B kinase activity [inference]

histone H2AX kinase activity [inference]

histone H2AXS139 kinase activity

protein serine kinase activity

catalytic activity, acting on a protein [inference]

protein kinase activity

protein serine/threonine kinase activity

protein tyrosine kinase activity

histone kinase activity [inference]

histone H2A kinase activity [inference]

histone H3 kinase activity [inference]

histone H4 kinase activity [inference]

histone H4S1 kinase activity

histone H2B kinase activity [inference]

histone H2AX kinase activity [inference]

histone H2AXS139 kinase activity

protein serine kinase activity

histone modifying activity [inference]

histone kinase activity [inference]

histone H2A kinase activity [inference]

histone H3 kinase activity [inference]

histone H4 kinase activity [inference]

histone H4S1 kinase activity

histone H2B kinase activity [inference]

histone H2AX kinase activity [inference]

histone H2AXS139 kinase activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

homeodomain-interacting protein kinase

Functional Category

O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
ATP binding
nucleotide binding

Displaying **all 4** entries
InterPro
Protein kinase domain
Protein kinase, ATP binding site
Protein kinase-like domain superfamily
Serine/threonine-protein kinase, active site

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Last updated: April 6, 2026