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sterol-C5-desaturase

Summary

Gene Symbol

SC5D

Organism

Odobenus rosmarus divergens (Pacific walrus)

External Links

NCBI Gene: 101367504
KEGG Gene ID: oro:101367504
PubChem: 101367504

Annotation

Keyword

Endoplasmic reticulum
Reference proteome
Sterol biosynthesis
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A2U3WUF5

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
cholesterol biosynthetic process via lathosterol	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

small molecule metabolic process [inference]

alcohol metabolic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

secondary alcohol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

organic substance metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

secondary alcohol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

Displaying **all 2** entries
GO Term	Evidence Code	PMID
oxidoreductase activity	IEA	22301074
iron ion binding	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

iron ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Carnivora

Group Name

GPCR family 3, C-terminal

Functional Category

H: Coenzyme transport and metabolism
I: Lipid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones

Displaying entries **1 - 10** of 13 in total

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Gene Ontology
C-4 methylsterol oxidase activity
C-5 sterol desaturase activity
cholesterol biosynthetic process via lathosterol
ergosterol biosynthetic process
iron ion binding
lipid biosynthetic process
oxidoreductase activity
sphingolipid biosynthetic process
sphingolipid delta-4 desaturase activity
sphingosine hydroxylase activity

Displaying 1 entry
InterPro
Fatty acid hydroxylase

KEGG BRITE Database

Orthology

K00227

Name

Delta7-sterol 5-desaturase [EC:1.14.19.20]

References

Ortholog

Displaying entries **1 - 10** of 43 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Canis lupus familiaris	610411	9615_1:000caf
Ailuropoda melanoleuca	100467645	9646_0:0021ea
Felis catus	101099997	9685_0:0030b9
Mustela putorius furo	101683752	9669_0:001a2e
Leptonychotes weddellii	102731354	9713_0:0053a5
Panthera tigris	102956406	9694_0:003078
Ursus maritimus	103662293	29073_0:00159a
Acinonyx jubatus	106976671	32536_0:001580
Panthera pardus	109278494	9691_0:000e24
Neomonachus schauinslandi	110586241	29088_0:003759

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024