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propionyl-CoA carboxylase subunit alpha

Summary

Gene Symbol

PCCA

Organism

Odobenus rosmarus divergens (Pacific walrus)

External Links

NCBI Gene: 101374318
KEGG Gene ID: oro:101374318
PubChem: 101374318

Annotation

Keyword

ATP-binding
Biotin
Ligase
Lipid degradation
Magnesium
Reference proteome
Transit peptide

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A0A2U3W9K2	Propanoyl-CoA:carbon dioxide ligase subunit alpha
A0A2U3W9L3	Propanoyl-CoA:carbon dioxide ligase subunit alpha
A0A2U3W9K0	Propanoyl-CoA:carbon dioxide ligase subunit alpha

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
mitochondrion	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying **all 3** entries
GO Term	Evidence Code	PMID
metal ion binding	IEA	22301074
propionyl-CoA carboxylase activity	IEA	30032202
ATP binding	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

ligase activity [inference]

ligase activity, forming carbon-carbon bonds [inference]

CoA carboxylase activity [inference]

propionyl-CoA carboxylase activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Carnivora

Group Name

propionyl-CoA carboxylase alpha chain, mitochondrial

Functional Category

C: Energy production and conversion
E: Amino acid transport and metabolism
I: Lipid transport and metabolism

Displaying **all 7** entries
Gene Ontology
ATP binding
ligase activity
metal ion binding
methylcrotonoyl-CoA carboxylase activity
nucleotide binding
propionyl-CoA carboxylase activity
urea carboxylase activity

Displaying entries **1 - 10** of 12 in total

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InterPro
ATP-grasp fold, subdomain 1
ATP-grasp fold
Biotin carboxylase, C-terminal
Biotin carboxylase-like, N-terminal domain
Biotin carboxylation domain
Biotin-binding site
Biotin/lipoyl attachment
Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain
Pre-ATP-grasp domain superfamily
Propionyl-coenzyme A carboxylase, BT domain

Rhea

RHEA:23720

hydrogencarbonate + ATP + propanoyl-CoA

H⁺ + phosphate + ADP + (S)-methylmalonyl-CoA

Enzyme

6.4.1.3

PMID

16492739

Ortholog

Displaying entries **1 - 10** of 43 in total

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Species	Gene ID	OrthoDB
Canis lupus familiaris	476975	9615_1:0039cb
Ailuropoda melanoleuca	100473163	9646_0:001fb4
Felis catus	101080758	9685_0:00035c
Mustela putorius furo	101692312	9669_0:001c42
Leptonychotes weddellii	102745019	9713_0:000f45
Panthera tigris	102970287	9694_0:0003e4
Ursus maritimus	103657568	29073_0:00068e
Acinonyx jubatus	106978322	32536_0:00017e
Panthera pardus	109264105	9691_0:000003
Neomonachus schauinslandi	110585904	29088_0:000b62

GlyTouCan

GlyComb

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UniCarb-DR

LM-GlycoRepo

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Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements