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ADAM metallopeptidase domain 10

Summary

Gene Symbol

ADAM10

Organism

Homo sapiens (human)

External Links

NCBI Gene

102

PubChem

102

Alliance of Genome Resources

HGNC:188

Annotation

Keyword

3D-structure
Alternative splicing
Alzheimer disease
Amyloidosis
Cell junction
Cell membrane
Cell projection
Cleavage on pair of basic residues
Cytoplasm
Cytoplasmic vesicle
Direct protein sequencing
Disease variant
Disulfide bond
Glycoprotein
Golgi apparatus
Metal-binding
Metalloprotease
Neurodegeneration
Notch signaling pathway
Phosphoprotein
Reference proteome
SH3-binding
Signal
Transmembrane helix
Zinc
Zymogen

Proteins

Displaying 1 entry
UniProt	Protein Name
O14672	CDw156 Kuzbanian protein homolog Mammalian disintegrin-metalloprotease

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 28 in total

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GO Term	Evidence Code	PMID
positive regulation of cell population proliferation	IMP	18373975
adherens junction organization	IEA
regulation of vasculature development	IEA
negative regulation of cell adhesion	IDA NAS	12714508 8694785
protein phosphorylation	ISS

GO Hierarchy

biological process

immune system process [inference]

leukocyte activation [inference]

myeloid leukocyte activation [inference]

monocyte activation

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

peptide metabolic process [inference]

peptide hormone processing [inference]

epidermal growth factor receptor ligand maturation

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

peptide hormone processing [inference]

epidermal growth factor receptor ligand maturation

protein metabolic process [inference]

proteolysis [inference]

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

epidermal growth factor receptor ligand maturation

membrane protein proteolysis [inference]

membrane protein ectodomain proteolysis

constitutive protein ectodomain proteolysis

protein catabolic process [inference]

protein catabolic process at synapse [inference]

protein catabolic process at postsynapse

protein modification process [inference]

protein phosphorylation

amyloid precursor protein metabolic process [inference]

amyloid precursor protein catabolic process

protein maturation [inference]

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

epidermal growth factor receptor ligand maturation

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

protein catabolic process at synapse [inference]

protein catabolic process at postsynapse

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

protein catabolic process at synapse [inference]

protein catabolic process at postsynapse

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

protein catabolic process at synapse [inference]

protein catabolic process at postsynapse

hormone metabolic process [inference]

peptide hormone processing [inference]

epidermal growth factor receptor ligand maturation

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

epidermal growth factor receptor ligand maturation

membrane protein proteolysis [inference]

membrane protein ectodomain proteolysis

constitutive protein ectodomain proteolysis

protein catabolic process [inference]

protein catabolic process at synapse [inference]

protein catabolic process at postsynapse

protein modification process [inference]

protein phosphorylation

amyloid precursor protein metabolic process [inference]

amyloid precursor protein catabolic process

protein maturation [inference]

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

epidermal growth factor receptor ligand maturation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

protein catabolic process at synapse [inference]

protein catabolic process at postsynapse

protein metabolic process [inference]

proteolysis [inference]

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

epidermal growth factor receptor ligand maturation

membrane protein proteolysis [inference]

membrane protein ectodomain proteolysis

constitutive protein ectodomain proteolysis

protein catabolic process [inference]

protein catabolic process at synapse [inference]

protein catabolic process at postsynapse

protein modification process [inference]

protein phosphorylation

amyloid precursor protein metabolic process [inference]

amyloid precursor protein catabolic process

protein maturation [inference]

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

epidermal growth factor receptor ligand maturation

macromolecule modification [inference]

protein modification process [inference]

protein phosphorylation

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

peptide hormone processing [inference]

epidermal growth factor receptor ligand maturation

protein metabolic process [inference]

proteolysis [inference]

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

epidermal growth factor receptor ligand maturation

membrane protein proteolysis [inference]

membrane protein ectodomain proteolysis

constitutive protein ectodomain proteolysis

protein catabolic process [inference]

protein catabolic process at synapse [inference]

protein catabolic process at postsynapse

protein modification process [inference]

protein phosphorylation

amyloid precursor protein metabolic process [inference]

amyloid precursor protein catabolic process

protein maturation [inference]

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

epidermal growth factor receptor ligand maturation

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

protein catabolic process at synapse [inference]

protein catabolic process at postsynapse

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

protein catabolic process at synapse [inference]

protein catabolic process at postsynapse

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

protein catabolic process at synapse [inference]

protein catabolic process at postsynapse

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

myeloid leukocyte activation [inference]

monocyte activation

cell communication [inference]

cell-cell signaling

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component disassembly [inference]

extracellular matrix disassembly

cellular component assembly [inference]

protein-containing complex assembly [inference]

pore complex assembly

cell junction organization [inference]

cell-cell junction organization [inference]

adherens junction organization

extracellular structure organization [inference]

extracellular matrix organization [inference]

extracellular matrix disassembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

pore complex assembly

external encapsulating structure organization [inference]

extracellular matrix organization [inference]

extracellular matrix disassembly

postsynapse organization

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

myeloid leukocyte activation [inference]

monocyte activation

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

developmental process [inference]

anatomical structure development [inference]

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

cochlea development

response to stimulus [inference]

response to chemical [inference]

response to organic substance [inference]

response to cytokine [inference]

response to tumor necrosis factor

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of T cell migration [inference]

positive regulation of T cell chemotaxis

regulation of leukocyte migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of T cell migration [inference]

positive regulation of T cell chemotaxis

regulation of leukocyte chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

regulation of lymphocyte chemotaxis [inference]

regulation of T cell chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

regulation of mononuclear cell migration [inference]

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of T cell migration [inference]

positive regulation of T cell chemotaxis

regulation of lymphocyte migration [inference]

regulation of lymphocyte chemotaxis [inference]

regulation of T cell chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of lymphocyte migration [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of T cell migration [inference]

positive regulation of T cell chemotaxis

regulation of T cell migration [inference]

regulation of T cell chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of T cell migration [inference]

positive regulation of T cell chemotaxis

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

negative regulation of gene expression

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

negative regulation of gene expression

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

negative regulation of gene expression

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway

signaling [inference]

cell-cell signaling

regulation of localization [inference]

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of protein localization to synapse [inference]

regulation of neurotransmitter receptor localization to postsynaptic specialization membrane

regulation of protein localization to cell periphery [inference]

regulation of neurotransmitter receptor localization to postsynaptic specialization membrane

regulation of protein localization to membrane [inference]

regulation of neurotransmitter receptor localization to postsynaptic specialization membrane

regulation of receptor localization to synapse [inference]

regulation of neurotransmitter receptor localization to postsynaptic specialization membrane

regulation of growth [inference]

regulation of cell growth [inference]

positive regulation of cell growth

positive regulation of growth [inference]

positive regulation of cell growth

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of T cell migration [inference]

positive regulation of T cell chemotaxis

regulation of chemotaxis [inference]

regulation of leukocyte chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

regulation of lymphocyte chemotaxis [inference]

regulation of T cell chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of T cell migration [inference]

positive regulation of T cell chemotaxis

regulation of leukocyte chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

regulation of lymphocyte chemotaxis [inference]

regulation of T cell chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

regulation of mononuclear cell migration [inference]

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of T cell migration [inference]

positive regulation of T cell chemotaxis

regulation of lymphocyte migration [inference]

regulation of lymphocyte chemotaxis [inference]

regulation of T cell chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of lymphocyte migration [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of T cell migration [inference]

positive regulation of T cell chemotaxis

regulation of T cell migration [inference]

regulation of T cell chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of T cell migration [inference]

positive regulation of T cell chemotaxis

positive regulation of cell migration

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of T cell migration [inference]

positive regulation of T cell chemotaxis

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of T cell migration [inference]

positive regulation of T cell chemotaxis

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of T cell migration [inference]

positive regulation of T cell chemotaxis

positive regulation of locomotion [inference]

positive regulation of chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of T cell migration [inference]

positive regulation of T cell chemotaxis

positive regulation of growth [inference]

positive regulation of cell growth

positive regulation of cellular process [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of T cell migration [inference]

positive regulation of T cell chemotaxis

positive regulation of response to stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cellular process [inference]

negative regulation of cell adhesion

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway

regulation of response to external stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

regulation of chemotaxis [inference]

regulation of leukocyte chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

regulation of lymphocyte chemotaxis [inference]

regulation of T cell chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of response to stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

regulation of developmental process [inference]

regulation of multicellular organismal development [inference]

regulation of vasculature development

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway

regulation of cell adhesion [inference]

negative regulation of cell adhesion

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

negative regulation of gene expression

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

positive regulation of cellular process [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of T cell migration [inference]

positive regulation of T cell chemotaxis

negative regulation of cellular process [inference]

negative regulation of cell adhesion

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

regulation of cellular component organization [inference]

regulation of cell growth [inference]

positive regulation of cell growth

regulation of synapse organization [inference]

regulation of postsynapse organization

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of protein localization to synapse [inference]

regulation of neurotransmitter receptor localization to postsynaptic specialization membrane

regulation of protein localization to cell periphery [inference]

regulation of neurotransmitter receptor localization to postsynaptic specialization membrane

regulation of protein localization to membrane [inference]

regulation of neurotransmitter receptor localization to postsynaptic specialization membrane

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of T cell migration [inference]

positive regulation of T cell chemotaxis

regulation of leukocyte chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

regulation of lymphocyte chemotaxis [inference]

regulation of T cell chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

regulation of mononuclear cell migration [inference]

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of T cell migration [inference]

positive regulation of T cell chemotaxis

regulation of lymphocyte migration [inference]

regulation of lymphocyte chemotaxis [inference]

regulation of T cell chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of lymphocyte migration [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of T cell migration [inference]

positive regulation of T cell chemotaxis

regulation of T cell migration [inference]

regulation of T cell chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of T cell migration [inference]

positive regulation of T cell chemotaxis

positive regulation of cell migration

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of T cell migration [inference]

positive regulation of T cell chemotaxis

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of T cell chemotaxis

positive regulation of T cell migration [inference]

positive regulation of T cell chemotaxis

regulation of multicellular organismal process [inference]

regulation of multicellular organismal development [inference]

regulation of vasculature development

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

peptide hormone processing [inference]

epidermal growth factor receptor ligand maturation

regulation of neurotransmitter receptor localization to postsynaptic specialization membrane

Displaying entries **1 - 5** of 24 in total

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GO Term	Evidence Code	PMID
membrane	HDA NAS	19946888 8694785
pore complex	IMP	30463011
Golgi apparatus	IDA	12475894
focal adhesion	HDA	21423176
postsynaptic density	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

pore complex

cellular anatomical entity [inference]

membrane

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

secretory granule membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

secretory granule membrane [inference]

plasma membrane region [inference]

synaptic membrane

cell junction [inference]

synapse [inference]

glutamatergic synapse

anchoring junction [inference]

cell-cell junction [inference]

adherens junction

cell-substrate junction [inference]

focal adhesion

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

Golgi-associated vesicle

coated vesicle [inference]

clathrin-coated vesicle

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

Golgi-associated vesicle

coated vesicle [inference]

clathrin-coated vesicle

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

Golgi-associated vesicle

coated vesicle [inference]

clathrin-coated vesicle

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

postsynaptic specialization [inference]

postsynaptic density

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
protein binding	IPI	10527948 15280379 17301176 19587294 20624979 23091066 23289620 23676497 25036101 26686862 30312582 30463011 30538620 31792032 32814053 32900848 33961781 34739841
integrin binding	NAS	8694785
metalloendopeptidase activity involved in amyloid precursor protein catabolic process	IBA IMP ISS	28164773
SH3 domain binding	IEA
signaling receptor binding	NAS	12176995

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

endopeptidase activity

metalloendopeptidase activity

metalloendopeptidase activity involved in amyloid precursor protein catabolic process

metallopeptidase activity

metalloendopeptidase activity

metalloendopeptidase activity involved in amyloid precursor protein catabolic process

metalloexopeptidase activity [inference]

metallodipeptidase activity

exopeptidase activity [inference]

metalloexopeptidase activity [inference]

metallodipeptidase activity

dipeptidase activity [inference]

metallodipeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

endopeptidase activity

metalloendopeptidase activity

metalloendopeptidase activity involved in amyloid precursor protein catabolic process

metallopeptidase activity

metalloendopeptidase activity

metalloendopeptidase activity involved in amyloid precursor protein catabolic process

metalloexopeptidase activity [inference]

metallodipeptidase activity

exopeptidase activity [inference]

metalloexopeptidase activity [inference]

metallodipeptidase activity

dipeptidase activity [inference]

metallodipeptidase activity

binding [inference]

protein binding

signaling receptor binding

integrin binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding

protein domain specific binding [inference]

SH3 domain binding

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

cell adhesion molecule binding [inference]

integrin binding

ion binding [inference]

cation binding [inference]

metal ion binding

protein-containing complex binding [inference]

integrin binding

molecular adaptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

uncharacterized protein

Functional Category

M: Cell wall/membrane/envelope biogenesis
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
membrane protein ectodomain proteolysis
metal ion binding
metalloendopeptidase activity
metallopeptidase activity
proteolysis

Displaying **all 5** entries
InterPro
ADAM10, cysteine-rich domain
Disintegrin domain superfamily
Disintegrin domain
Metallopeptidase, catalytic domain superfamily
Peptidase M12B, ADAM/reprolysin

Disease

Disease Ontology

Displaying **all 9** entries
DO ID	Disease Name	Source
DOID:0050700	cardiomyopathy	Alliance of Genome Resources
DOID:0060258	reticulate acropigmentation of Kitamura	Alliance of Genome Resources
DOID:0081292	traumatic brain injury	Alliance of Genome Resources
DOID:0110050	Alzheimer's disease 18	Alliance of Genome Resources
DOID:10652	Alzheimer's disease	Alliance of Genome Resources
DOID:14004	thoracic aortic aneurysm	Alliance of Genome Resources
DOID:1824	status epilepticus	Alliance of Genome Resources
DOID:83	cataract	Alliance of Genome Resources
DOID:9256	colorectal cancer	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 85 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	11487	MGI:109548	MOUSE63940
Rattus norvegicus	29650	RGD:2032	RATNO40901
Drosophila melanogaster	34772	FB:FBgn0259984
Drosophila melanogaster	43501	FB:FBgn0039688
Caenorhabditis elegans	172689	WB:WBGene00006324
Bos taurus	282132		BOVIN01267
Danio rerio	393392	ZFIN:ZDB-GENE-071115-1
Sus scrofa	397345		PIGXX14228
Xenopus laevis	399187	Xenbase:XB-GENE-945394
Danio rerio	566044	ZFIN:ZDB-GENE-040917-2

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements