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reversion inducing cysteine rich protein with kazal motifs

Summary

Gene Symbol

RECK

Organism

Columba livia (rock pigeon)

External Links

NCBI Gene: 102083569
KEGG Gene ID: clv:102083569
PubChem: 102083569

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
blood vessel maturation	IEA	30032202
sprouting angiogenesis	IEA	30032202
extracellular matrix organization	IEA	30032202
negative regulation of metalloendopeptidase activity	IEA	30032202

GO Hierarchy

biological process

cellular process [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

extracellular structure organization [inference]

extracellular matrix organization

external encapsulating structure organization [inference]

extracellular matrix organization

developmental process [inference]

developmental maturation [inference]

anatomical structure maturation [inference]

blood vessel maturation

anatomical structure formation involved in morphogenesis [inference]

angiogenesis [inference]

sprouting angiogenesis

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of nitrogen compound metabolic process [inference]

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of peptidase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of endopeptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of metalloendopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of metallopeptidase activity [inference]

regulation of metalloendopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of peptidase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of endopeptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of metalloendopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of metallopeptidase activity [inference]

regulation of metalloendopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of peptidase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of endopeptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of metalloendopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of metallopeptidase activity [inference]

regulation of metalloendopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of molecular function [inference]

negative regulation of molecular function [inference]

negative regulation of catalytic activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of catalytic activity [inference]

negative regulation of catalytic activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of hydrolase activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of peptidase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of endopeptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of metalloendopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of metallopeptidase activity [inference]

regulation of metalloendopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

Displaying 1 entry
GO Term	Evidence Code	PMID
plasma membrane	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein binding	IEA	22301074
metalloendopeptidase inhibitor activity	IEA	30032202

GO Hierarchy

molecular function

binding [inference]

protein binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity [inference]

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity [inference]

metalloendopeptidase inhibitor activity

peptidase regulator activity [inference]

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity [inference]

metalloendopeptidase inhibitor activity

endopeptidase regulator activity [inference]

endopeptidase inhibitor activity [inference]

metalloendopeptidase inhibitor activity

molecular function inhibitor activity [inference]

enzyme inhibitor activity [inference]

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity [inference]

metalloendopeptidase inhibitor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Reversion-inducing cysteine-rich protein

Functional Category

E: Amino acid transport and metabolism
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
blood vessel maturation
endopeptidase inhibitor activity
extracellular matrix organization
metalloendopeptidase inhibitor activity
sprouting angiogenesis

Displaying **all 3** entries
InterPro
Kazal domain superfamily
Kazal domain
Reversion-inducing cysteine-rich protein with Kazal motifs

KEGG BRITE Database

Orthology

K17461

Name

reversion-inducing-cysteine-rich protein with kazal motifs

References

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026

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External Links

OrthoDB (Group)

KEGG BRITE Database

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Acknowledgements