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3-hydroxybutyrate dehydrogenase 2

Summary

Gene Symbol

BDH2

Organism

Capra hircus (goat)

External Links

NCBI Gene: 102173540
KEGG Gene ID: chx:102173540
PubChem: 102173540

Annotation

Keyword

NAD
Oxidoreductase
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A452F8L8	(R)-beta-hydroxybutyrate dehydrogenase 3-hydroxybutyrate dehydrogenase type 2 4-oxo-L-proline reductase Oxidoreductase UCPA Short chain dehydrogenase/reductase family 15C member 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
siderophore biosynthetic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

nonribosomal peptide biosynthetic process [inference]

siderophore biosynthetic process

amide metabolic process [inference]

peptide metabolic process [inference]

peptide biosynthetic process [inference]

nonribosomal peptide biosynthetic process [inference]

siderophore biosynthetic process

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

nonribosomal peptide biosynthetic process [inference]

siderophore biosynthetic process

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

peptide biosynthetic process [inference]

nonribosomal peptide biosynthetic process [inference]

siderophore biosynthetic process

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

nonribosomal peptide biosynthetic process [inference]

siderophore biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

nonribosomal peptide biosynthetic process [inference]

siderophore biosynthetic process

secondary metabolite biosynthetic process [inference]

siderophore biosynthetic process

organic substance biosynthetic process [inference]

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

nonribosomal peptide biosynthetic process [inference]

siderophore biosynthetic process

secondary metabolic process [inference]

siderophore metabolic process [inference]

siderophore biosynthetic process

secondary metabolite biosynthetic process [inference]

siderophore biosynthetic process

cellular metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

nonribosomal peptide biosynthetic process [inference]

siderophore biosynthetic process

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

nonribosomal peptide biosynthetic process [inference]

siderophore biosynthetic process

organic substance metabolic process [inference]

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

peptide biosynthetic process [inference]

nonribosomal peptide biosynthetic process [inference]

siderophore biosynthetic process

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

nonribosomal peptide biosynthetic process [inference]

siderophore biosynthetic process

organic substance biosynthetic process [inference]

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

nonribosomal peptide biosynthetic process [inference]

siderophore biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

nonribosomal peptide biosynthetic process [inference]

siderophore biosynthetic process

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

nonribosomal peptide biosynthetic process [inference]

siderophore biosynthetic process

Displaying 1 entry
GO Term	Evidence Code	PMID
cytoplasm	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

Displaying 1 entry
GO Term	Evidence Code	PMID
3-hydroxybutyrate dehydrogenase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

3-hydroxybutyrate dehydrogenase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

3-oxoacyl-

Functional Category

E: Amino acid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
oxidoreductase activity

Displaying **all 3** entries
InterPro
NAD(P)-binding domain superfamily
Short-chain dehydrogenase/reductase SDR
Short-chain dehydrogenase/reductase, conserved site

KEGG BRITE Database

Orthology

K25939

Name

4-oxoproline reductase [EC:1.1.1.104]

References

35150746

Rhea

RHEA:20521

(R)-3-hydroxybutanoate + NAD⁺

acetoacetate + H⁺ + NADH

Enzyme

1.1.1.30

PMID

RHEA:13601

NAD⁺ + cis-4-hydroxy-L-proline

H⁺ + NADH + 4-oxo-L-proline

Enzyme

1.1.1.104

PMID

Ortholog

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Homo sapiens	56898		HUMAN76834
Mus musculus	69772		MOUSE37844
Rattus norvegicus	295458		RATNO25294
Pan troglodytes	461412		PANTR34233
Pan troglodytes	462895		PANTR34233
Bos taurus	515321	9913_0:001396	BOVIN31125
Danio rerio	550507		DANRE16598
Macaca mulatta	711108		MACMU37573
Monodelphis domestica	100012027		MONDO26430
Ornithorhynchus anatinus	100076108		ORNAN03798

GlyTouCan

GlyComb

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UniCarb-DR

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Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

International Collaboration

Acknowledgements