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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
growth differentiation factor 11
Summary
- Gene Symbol
-
- GDF11
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Cleavage on pair of basic residues
- Cytokine
- Disease variant
- Disulfide bond
- Glycoprotein
- Growth factor
- Reference proteome
- Secreted
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| O95390 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| cell population proliferation | ||
| roof of mouth development | ||
| negative regulation of cell population proliferation | ||
| SMAD protein signal transduction |
|
|
| camera-type eye morphogenesis |
GO Hierarchy
biological process
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein-containing complex | ||
| intracellular membrane-bounded organelle | ||
| nucleoplasm | ||
| extracellular space |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| cytokine activity | ||
| growth factor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Growth/differentiation factor 8
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| cytokine activity |
| growth factor activity |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0070418 | vertebral hypersegmentation and orofacial anomalies |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 14561 | MGI:1338027 | MOUSE01634 | ||
| 29454 | RGD:2673 | RATNO39062 | ||
| 43811 | FB:FBgn0026199 | |||
| 175237 | WB:WBGene00000903 | |||
| 397254 | PIGXX25557 | |||
| 406247 | ZFIN:ZDB-GENE-040427-2 | DANRE01708 | ||
| 451970 | 9598_0:0036ba | PANTR05635 | ||
| 540517 | BOVIN29670 | |||
| 707708 | MACMU04200 | |||
| 100058832 | HORSE36000 |
