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ATP binding cassette subfamily C member 4 (PEL blood group)

Summary

Gene Symbol

ABCC4

Organism

Homo sapiens (human)

External Links

NCBI Gene

10257

PubChem

10257

Alliance of Genome Resources

HGNC:55

JoGo

ABCC4

TogoVar

ABCC4

Annotation

Keyword

3D-structure
ATP-binding
Alternative splicing
Cell membrane
Disease variant
Glycoprotein
Lipid transport
Magnesium
Metal-binding
Phosphoprotein
Proteomics identification
Reference proteome
Repeat
Translocase
Transmembrane helix
Transport

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A8K2Q2
O15439	MRP/cMOAT-related ABC transporter Multi-specific organic anion transporter B Multidrug resistance-associated protein 4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 18 in total

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GO Term	Evidence Code	PMID
platelet degranulation	TAS
xenobiotic metabolic process	TAS
xenobiotic transmembrane transport	TAS
bile acid and bile salt transport	IMP	16282361
prostaglandin transport	IMP	15364914

GO Hierarchy

biological process

metabolic process [inference]

cellular metabolic process [inference]

xenobiotic metabolic process

cellular process [inference]

vesicle-mediated transport [inference]

exocytosis [inference]

regulated exocytosis [inference]

platelet degranulation

cellular metabolic process [inference]

xenobiotic metabolic process

transmembrane transport

xenobiotic transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic anion transmembrane transport

glutathione transmembrane transport

purine-containing compound transmembrane transport [inference]

guanine nucleotide transmembrane transport

export across plasma membrane

nucleotide transmembrane transport [inference]

guanine nucleotide transmembrane transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cilium organization [inference]

cilium assembly

organelle assembly [inference]

cilium assembly

cellular component assembly [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly

organelle assembly [inference]

cilium assembly

cell projection organization [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly

plasma membrane bounded cell projection organization [inference]

cilium organization [inference]

cilium assembly

plasma membrane bounded cell projection assembly [inference]

cilium assembly

export from cell [inference]

secretion by cell [inference]

exocytosis [inference]

regulated exocytosis [inference]

platelet degranulation

signal release [inference]

prostaglandin secretion

export across plasma membrane

lipid export from cell [inference]

prostaglandin secretion

multicellular organismal process [inference]

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

vascular transport [inference]

transport across blood-brain barrier

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic anion transport [inference]

monoatomic anion transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic anion transmembrane transport

vascular transport [inference]

transport across blood-brain barrier

vesicle-mediated transport [inference]

exocytosis [inference]

regulated exocytosis [inference]

platelet degranulation

xenobiotic transport [inference]

xenobiotic transmembrane transport

secretion [inference]

icosanoid secretion [inference]

prostaglandin secretion

secretion by cell [inference]

exocytosis [inference]

regulated exocytosis [inference]

platelet degranulation

signal release [inference]

prostaglandin secretion

transmembrane transport

xenobiotic transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic anion transmembrane transport

glutathione transmembrane transport

purine-containing compound transmembrane transport [inference]

guanine nucleotide transmembrane transport

export across plasma membrane

nucleotide transmembrane transport [inference]

guanine nucleotide transmembrane transport

organic substance transport [inference]

lipid transport [inference]

bile acid and bile salt transport

fatty acid transport [inference]

prostaglandin transport

prostaglandin secretion

lipid export from cell [inference]

prostaglandin secretion

organic anion transport [inference]

urate transport

glutathione transport [inference]

glutathione transmembrane transport

carboxylic acid transport [inference]

monocarboxylic acid transport [inference]

bile acid and bile salt transport

fatty acid transport [inference]

prostaglandin transport

prostaglandin secretion

icosanoid transport [inference]

prostaglandin transport

prostaglandin secretion

icosanoid secretion [inference]

prostaglandin secretion

leukotriene transport

cAMP transport

organophosphate ester transport [inference]

nucleotide transport [inference]

purine nucleotide transport [inference]

guanine nucleotide transport [inference]

guanine nucleotide transmembrane transport

purine ribonucleotide transport [inference]

cAMP transport

adenine nucleotide transport [inference]

cAMP transport

cyclic nucleotide transport [inference]

cAMP transport

nucleotide transmembrane transport [inference]

guanine nucleotide transmembrane transport

organic acid transport [inference]

carboxylic acid transport [inference]

monocarboxylic acid transport [inference]

bile acid and bile salt transport

fatty acid transport [inference]

prostaglandin transport

prostaglandin secretion

icosanoid transport [inference]

prostaglandin transport

prostaglandin secretion

icosanoid secretion [inference]

prostaglandin secretion

leukotriene transport

organic hydroxy compound transport [inference]

bile acid and bile salt transport

nucleobase-containing compound transport [inference]

nucleotide transport [inference]

purine nucleotide transport [inference]

guanine nucleotide transport [inference]

guanine nucleotide transmembrane transport

purine ribonucleotide transport [inference]

cAMP transport

adenine nucleotide transport [inference]

cAMP transport

cyclic nucleotide transport [inference]

cAMP transport

nucleotide transmembrane transport [inference]

guanine nucleotide transmembrane transport

purine-containing compound transmembrane transport [inference]

guanine nucleotide transmembrane transport

carbohydrate derivative transport [inference]

purine ribonucleotide transport [inference]

cAMP transport

nitrogen compound transport [inference]

urate transport

nucleobase-containing compound transport [inference]

nucleotide transport [inference]

purine nucleotide transport [inference]

guanine nucleotide transport [inference]

guanine nucleotide transmembrane transport

purine ribonucleotide transport [inference]

cAMP transport

adenine nucleotide transport [inference]

cAMP transport

cyclic nucleotide transport [inference]

cAMP transport

nucleotide transmembrane transport [inference]

guanine nucleotide transmembrane transport

purine-containing compound transmembrane transport [inference]

guanine nucleotide transmembrane transport

export from cell [inference]

secretion by cell [inference]

exocytosis [inference]

regulated exocytosis [inference]

platelet degranulation

signal release [inference]

prostaglandin secretion

export across plasma membrane

lipid export from cell [inference]

prostaglandin secretion

establishment of localization in cell [inference]

platelet degranulation

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
nucleolus	IDA
Golgi apparatus	IDA
plasma membrane	TAS
plasma membrane	IDA	15297306 18619525 23137377 25173977 28112518
plasma membrane	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

secretory granule membrane [inference]

platelet dense granule membrane

bounding membrane of organelle [inference]

secretory granule membrane [inference]

platelet dense granule membrane

plasma membrane region [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

Golgi apparatus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

nucleolus

intracellular organelle [inference]

intracellular membrane-bounded organelle

Golgi apparatus

intracellular non-membrane-bounded organelle [inference]

nucleolus

side of membrane [inference]

external side of plasma membrane [inference]

external side of apical plasma membrane

Displaying entries **1 - 5** of 20 in total

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GO Term	Evidence Code	PMID
guanine nucleotide transmembrane transporter activity	IDA	15454390
protein binding	IPI	22411990 29146910
ATP binding	IEA
ABC-type xenobiotic transporter activity	IEA
prostaglandin transmembrane transporter activity	IMP	15364914