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A-kinase anchoring protein 8

Summary

Gene Symbol

AKAP8

Organism

Homo sapiens (human)

External Links

NCBI Gene

10270

PubChem

10270

Alliance of Genome Resources

HGNC:378

JoGo

AKAP8

TogoVar

AKAP8

Annotation

Keyword

Cytoplasm
DNA-binding
Innate immunity
Isopeptide bond
Methylation
Nucleus
Phosphoprotein
Protein transport
Proteomics identification
Reference proteome
Repeat
Transcription regulation
Ubl conjugation
Zinc-finger

Proteins

Displaying 1 entry
UniProt	Protein Name
O43823	A-kinase anchor protein 95 kDa

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
mitotic cell cycle	TAS	9473338
mitotic chromosome condensation	IEA
signal transduction	TAS	9473338
protein transport	IEA
negative regulation of tumor necrosis factor production	IEA

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

innate immune response

cellular process [inference]

cell cycle [inference]

mitotic cell cycle

signal transduction

cell cycle process [inference]

cell cycle phase transition [inference]

cell cycle G2/M phase transition

mitotic cell cycle process [inference]

mitotic chromosome condensation

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

cellular response to alcohol [inference]

cellular response to prostaglandin E stimulus

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to alcohol [inference]

cellular response to prostaglandin E stimulus

cellular response to ketone [inference]

cellular response to prostaglandin E stimulus

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

chromosome organization [inference]

chromosome condensation [inference]

mitotic chromosome condensation

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

innate immune response

immune response [inference]

innate immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to other organism [inference]

defense response to other organism [inference]

innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to other organism [inference]

defense response to other organism [inference]

innate immune response

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to endogenous stimulus [inference]

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

response to prostaglandin [inference]

response to prostaglandin E [inference]

cellular response to prostaglandin E stimulus

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

cellular response to endogenous stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

response to chemical [inference]

response to organic substance [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

response to prostaglandin [inference]

response to prostaglandin E [inference]

cellular response to prostaglandin E stimulus

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

response to lipid [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

response to prostaglandin [inference]

response to prostaglandin E [inference]

cellular response to prostaglandin E stimulus

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

cellular response to alcohol [inference]

cellular response to prostaglandin E stimulus

response to alcohol [inference]

response to prostaglandin E [inference]

cellular response to prostaglandin E stimulus

cellular response to alcohol [inference]

cellular response to prostaglandin E stimulus

response to ketone [inference]

response to prostaglandin E [inference]

cellular response to prostaglandin E stimulus

cellular response to ketone [inference]

cellular response to prostaglandin E stimulus

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

cellular response to alcohol [inference]

cellular response to prostaglandin E stimulus

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to alcohol [inference]

cellular response to prostaglandin E stimulus

cellular response to ketone [inference]

cellular response to prostaglandin E stimulus

response to oxygen-containing compound [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

response to alcohol [inference]

response to prostaglandin E [inference]

cellular response to prostaglandin E stimulus

cellular response to alcohol [inference]

cellular response to prostaglandin E stimulus

response to ketone [inference]

response to prostaglandin E [inference]

cellular response to prostaglandin E stimulus

cellular response to ketone [inference]

cellular response to prostaglandin E stimulus

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to alcohol [inference]

cellular response to prostaglandin E stimulus

cellular response to ketone [inference]

cellular response to prostaglandin E stimulus

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

cellular response to alcohol [inference]

cellular response to prostaglandin E stimulus

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to alcohol [inference]

cellular response to prostaglandin E stimulus

cellular response to ketone [inference]

cellular response to prostaglandin E stimulus

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

establishment of localization [inference]

transport [inference]

organic substance transport [inference]

protein transport

nitrogen compound transport [inference]

protein transport

establishment of protein localization [inference]

protein transport

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production [inference]

negative regulation of tumor necrosis factor production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production [inference]

negative regulation of tumor necrosis factor production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production [inference]

negative regulation of tumor necrosis factor production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of cellular process [inference]

signal transduction

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production [inference]

negative regulation of tumor necrosis factor production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production [inference]

negative regulation of tumor necrosis factor production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
condensed chromosome	IEA
female pronucleus	IEA
nucleus	IBA
nucleoplasm	IDA
nucleolus	IDA	26683827

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

pronucleus [inference]

female pronucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

chromosome [inference]

condensed chromosome

nucleolus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

pronucleus [inference]

female pronucleus

intracellular non-membrane-bounded organelle [inference]

chromosome [inference]

condensed chromosome

nucleolus

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
double-stranded DNA binding	IEA
RNA binding	HDA	22658674 22681889
protein binding	IPI	12740381 16227597 16980585 22130794 23995757 33961781 9473338
zinc ion binding	IEA
protein kinase A regulatory subunit binding	IBA