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alpha 1,4-galactosyltransferase (P1PK blood group)

Summary

Gene Symbol

A4GALT

Organism

Balaenoptera acutorostrata (minke whale)

External Links

NCBI Gene: 103010830
KEGG Gene ID: bacu:103010830
PubChem: 103010830

Annotation

Keyword

Glycosyltransferase
Golgi apparatus
Lipid biosynthesis
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A384AP94	Alpha-1,4-N-acetylglucosaminyltransferase Alpha-1,4-galactosyltransferase Globotriaosylceramide synthase UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
protein O-linked glycosylation	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

Displaying 1 entry
GO Term	Evidence Code	PMID
acetylglucosaminyltransferase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

acetylglucosaminyltransferase activity

hexosyltransferase activity [inference]

acetylglucosaminyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Cetacea

Group Name

lactosylceramide 4-alpha-galactosyltransferase

Functional Category

H: Coenzyme transport and metabolism
J: Translation, ribosomal structure and biogenesis
M: Cell wall/membrane/envelope biogenesis

Displaying **all 4** entries
Gene Ontology
galactosyltransferase activity
glycosphingolipid biosynthetic process
hexosyltransferase activity
lipid metabolic process

Displaying **all 3** entries
InterPro
Alpha 1,4-glycosyltransferase domain
Glycosyltransferase, DXD sugar-binding motif
Nucleotide-diphospho-sugar transferases

KEGG BRITE Database

Orthology

K01988

Name

lactosylceramide 4-alpha-galactosyltransferase [EC:2.4.1.228]

References

10748143

Reactions

Displaying **all 3** entries
KEGG Reaction	Enzyme	Acceptor	Product
R11375	2.4.1.228	G58896AZ	G12460DL
R11376	2.4.1.228	G00061MO	G33020YH
R05960	2.4.1.228	G84224TW	G00059MO

Rhea

RHEA:11924

a β-D-Gal-(1→4)-β-D-Glc-(1↔1)-Cer(d18:1(4E)) + UDP-α-D-galactose

H⁺ + a globoside Gb3Cer (d18:1(4E)) + UDP

Enzyme

2.4.1.228

PMID

Ortholog

Displaying entries **1 - 10** of 13 in total

1

2

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Species	Gene ID	OrthoDB
Orcinus orca	101275372	9733_0:002ace
Tursiops truncatus	101324228	9739_0:002c07
Physeter catodon	102992800	9755_0:004821
Lipotes vexillifer	103069366	118797_0:0016a7
Delphinapterus leucas	111186415	9749_0:0044c6
Neophocaena asiaeorientalis asiaeorientalis	112394638	1706337_0:000785
Lagenorhynchus obliquidens	113621119	90247_0:000e87
Monodon monoceros	114884967	40151_0:003e1b
Globicephala melas	115852704	9731_0:000781
Phocoena sinus	116760331	42100_0:002e54

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Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

International Collaboration

Acknowledgements