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Guidelines
MIRAGE
cytochrome P450 family 17 subfamily A member 1

Summary
Gene Symbol
  • CYP17A1
Organism
Chlorocebus sabaeus (green monkey)
NCBI Gene
103216445
KEGG Gene ID
csab:103216445
PubChem
103216445
Annotation
Keyword
  • Heme
  • Lipid metabolism
  • Lyase
  • Membrane
  • Microsome
  • Monooxygenase
  • Reference proteome
  • Signal
  • Steroidogenesis
Proteins
Displaying 1 entry
UniProt Protein Name
A0A0D9QZC0
  • CYPXVII
  • Cytochrome P450 17A1
  • Cytochrome P450-C17
  • Steroid 17-alpha-monooxygenase
Annotation information from UniProt.
Gene Ontology (GO)
Displaying all 2 entries
GO Term Evidence Code PMID
hormone biosynthetic process
progesterone metabolic process
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
KEGG BRITE Database
Orthology
K00512
Name
steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase [EC:1.14.14.19 1.14.14.32]
References
Rhea

RHEA:50236

O2 + pregnenolone
H2O + H+ + 17α-hydroxypregnenolone
Enzyme
PMID

RHEA:65760

O2 + a C21-steroid
a 17α-hydroxy-C21-steroid + H2O + H+
Enzyme
PMID

RHEA:46308

O2 + progesterone
H2O + H+ + 17α-hydroxyprogesterone
Enzyme
PMID

RHEA:50244

O2 + 17α-hydroxypregnenolone
H2O + H+ + 3β-hydroxyandrost-5-en-17-one + acetate
Enzyme
PMID

RHEA:14753

O2 + 17α-hydroxyprogesterone
H2O + H+ + androst-4-ene-3,17-dione + acetate
Enzyme
PMID
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026