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hydroxyacylglutathione hydrolase

Summary

Gene Symbol

HAGH

Organism

Chlorocebus sabaeus (green monkey)

External Links

NCBI Gene: 103226359
KEGG Gene ID: csab:103226359
PubChem: 103226359

Annotation

Keyword

Hydrolase
Metal-binding
Mitochondrion
Reference proteome
Transit peptide
Zinc

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A0D9RFU8	Glyoxalase II

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione	IEA	22301074
glutathione metabolic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

cellular catabolic process [inference]

ketone catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

aldehyde catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

small molecule catabolic process [inference]

ketone catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

organic substance catabolic process [inference]

ketone catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

aldehyde catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

cellular metabolic process [inference]

cellular aldehyde metabolic process [inference]

methylglyoxal metabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

aldehyde catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

lactate metabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

cellular ketone metabolic process [inference]

methylglyoxal metabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

ketone catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

cellular catabolic process [inference]

ketone catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

aldehyde catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

lactate metabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

cellular ketone metabolic process [inference]

methylglyoxal metabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

ketone catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

small molecule catabolic process [inference]

ketone catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

organic substance metabolic process [inference]

cellular aldehyde metabolic process [inference]

methylglyoxal metabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

aldehyde catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

lactate metabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

glutathione metabolic process

cellular ketone metabolic process [inference]

methylglyoxal metabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

ketone catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

organic substance catabolic process [inference]

ketone catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

aldehyde catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

organic hydroxy compound metabolic process [inference]

lactate metabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

cellular process [inference]

cellular metabolic process [inference]

cellular aldehyde metabolic process [inference]

methylglyoxal metabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

aldehyde catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

lactate metabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

cellular ketone metabolic process [inference]

methylglyoxal metabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

ketone catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

cellular catabolic process [inference]

ketone catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

aldehyde catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

Displaying 1 entry
GO Term	Evidence Code	PMID
mitochondrion	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying 1 entry
GO Term	Evidence Code	PMID
hydroxyacylglutathione hydrolase activity	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

thiolester hydrolase activity [inference]

hydroxyacylglutathione hydrolase activity

Gene Ontology information from NCBI Gene and UniProt.

Rhea

H₂O + (R)-S-lactoylglutathione

H⁺ + (R)-lactate + glutathione

Enzyme

3.1.2.6

PMID

H₂O + an S-(2-hydroxyacyl)glutathione

H⁺ + glutathione + a 2-hydroxy carboxylate

Enzyme

3.1.2.6

PMID

Ortholog

Displaying entries **1 - 10** of 59 in total

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Next ›

Last »
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Latimeria chalumnae	102365938		LATCH08483
Danio rerio	336977		DANRE30607
Ictalurus punctatus	108254978		ICTPU24931
Gadus morhua	115530698		GADMO39219
Oreochromis niloticus	100699784		ORENI53575
Chrysemys picta bellii	101939520		CHRPI01555
Crocodylus porosus	109314639		CROPO22986
Pseudonaja textilis	113438643		PSETE10403
Serinus canaria	103817575		SERCA11654
Ornithorhynchus anatinus	100091202		ORNAN14011

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024