GlyCosmos Portal

Submissions

ATP binding cassette subfamily A member 7

Summary

Gene Symbol

ABCA7

Organism

Homo sapiens (human)

External Links

NCBI Gene

10347

PubChem

10347

Alliance of Genome Resources

HGNC:37

Annotation

Keyword

3D-structure
ATP-binding
Alternative splicing
Alzheimer disease
Amyloidosis
Cell membrane
Cell projection
Cytoplasm
Disulfide bond
Endoplasmic reticulum
Endosome
Glycoprotein
Golgi apparatus
Lipid transport
Neurodegeneration
Phagocytosis
Reference proteome
Repeat
Translocase
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
B3KUJ3
Q8IZY2	ABCA-SSN ATP-binding cassette sub-family A member 7 Autoantigen SS-N Macrophage ABC transporter

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 28 in total

1

2

3

4

5

6

Next ›

Last »
GO Term	Evidence Code	PMID
negative regulation of MAPK cascade	ISS
negative regulation of PERK-mediated unfolded protein response	ISS
positive regulation of cholesterol efflux	ISS
amyloid-beta formation	IMP	26260791
regulation of amyloid precursor protein catabolic process	IMP	26260791

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

peptide metabolic process [inference]

amyloid-beta metabolic process [inference]

amyloid-beta formation

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

amyloid-beta metabolic process [inference]

amyloid-beta formation

protein metabolic process [inference]

protein modification process [inference]

peptide cross-linking

amyloid precursor protein metabolic process [inference]

amyloid precursor protein catabolic process [inference]

amyloid-beta formation

catabolic process [inference]

cellular catabolic process [inference]

amyloid-beta clearance by cellular catabolic process

cellular metabolic process [inference]

cellular catabolic process [inference]

amyloid-beta clearance by cellular catabolic process

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

peptide cross-linking

amyloid precursor protein metabolic process [inference]

amyloid precursor protein catabolic process [inference]

amyloid-beta formation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

peptide cross-linking

amyloid precursor protein metabolic process [inference]

amyloid precursor protein catabolic process [inference]

amyloid-beta formation

macromolecule modification [inference]

protein modification process [inference]

peptide cross-linking

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

amyloid-beta metabolic process [inference]

amyloid-beta formation

protein metabolic process [inference]

protein modification process [inference]

peptide cross-linking

amyloid precursor protein metabolic process [inference]

amyloid precursor protein catabolic process [inference]

amyloid-beta formation

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

apolipoprotein A-I-mediated signaling pathway

vesicle-mediated transport [inference]

endocytosis [inference]

phagocytosis

cellular metabolic process [inference]

cellular catabolic process [inference]

amyloid-beta clearance by cellular catabolic process

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus

transmembrane transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein-lipid complex assembly [inference]

plasma lipoprotein particle assembly [inference]

high-density lipoprotein particle assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein-lipid complex assembly [inference]

plasma lipoprotein particle assembly [inference]

high-density lipoprotein particle assembly

protein-lipid complex organization [inference]

protein-lipid complex assembly [inference]

plasma lipoprotein particle assembly [inference]

high-density lipoprotein particle assembly

plasma lipoprotein particle organization [inference]

plasma lipoprotein particle assembly [inference]

high-density lipoprotein particle assembly

membrane organization [inference]

membrane raft organization [inference]

plasma membrane raft organization

regulation of membrane lipid distribution [inference]

lipid translocation [inference]

phospholipid translocation

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition [inference]

learning or memory [inference]

learning [inference]

associative learning [inference]

visual learning

memory

behavior [inference]

learning or memory [inference]

learning [inference]

associative learning [inference]

visual learning

memory

visual behavior [inference]

visual learning

plasma lipoprotein particle organization [inference]

plasma lipoprotein particle assembly [inference]

high-density lipoprotein particle assembly

amyloid-beta clearance [inference]

amyloid-beta clearance by cellular catabolic process

response to stimulus [inference]

response to abiotic stimulus [inference]

response to radiation [inference]

response to light stimulus [inference]

visual behavior [inference]

visual learning

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

phagocytosis

transmembrane transport

organic substance transport [inference]

lipid transport [inference]

phospholipid transport [inference]

sterol transport [inference]

cholesterol transport [inference]

cholesterol efflux

lipid translocation [inference]

phospholipid translocation

organophosphate ester transport [inference]

phospholipid transport [inference]

organic hydroxy compound transport [inference]

sterol transport [inference]

cholesterol transport [inference]

cholesterol efflux

import into cell [inference]

endocytosis [inference]

phagocytosis

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

regulation of glycoprotein biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

regulation of amyloid precursor protein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

negative regulation of protein metabolic process [inference]

negative regulation of amyloid precursor protein catabolic process [inference]

negative regulation of amyloid-beta formation

negative regulation of glycoprotein metabolic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of amide metabolic process [inference]

negative regulation of amyloid-beta formation

negative regulation of protein metabolic process [inference]

negative regulation of amyloid precursor protein catabolic process [inference]

negative regulation of amyloid-beta formation

negative regulation of glycoprotein metabolic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

regulation of glycoprotein biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

regulation of amyloid precursor protein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

regulation of nitrogen compound metabolic process [inference]

regulation of amide metabolic process [inference]

negative regulation of amide metabolic process [inference]

negative regulation of amyloid-beta formation

regulation of amyloid-beta formation [inference]

negative regulation of amyloid-beta formation

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of amide metabolic process [inference]

negative regulation of amyloid-beta formation

negative regulation of protein metabolic process [inference]

negative regulation of amyloid precursor protein catabolic process [inference]

negative regulation of amyloid-beta formation

negative regulation of glycoprotein metabolic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

regulation of protein metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of amyloid precursor protein catabolic process [inference]

negative regulation of amyloid-beta formation

negative regulation of glycoprotein metabolic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

regulation of amyloid precursor protein catabolic process

regulation of amyloid-beta formation [inference]

negative regulation of amyloid-beta formation

negative regulation of amyloid precursor protein catabolic process [inference]

negative regulation of amyloid-beta formation

regulation of glycoprotein metabolic process [inference]

regulation of glycoprotein biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

regulation of amyloid precursor protein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

negative regulation of glycoprotein metabolic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

regulation of glycoprotein biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

regulation of amyloid precursor protein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

negative regulation of protein metabolic process [inference]

negative regulation of amyloid precursor protein catabolic process [inference]

negative regulation of amyloid-beta formation

negative regulation of glycoprotein metabolic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

regulation of protein metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of amyloid precursor protein catabolic process [inference]

negative regulation of amyloid-beta formation

negative regulation of glycoprotein metabolic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

regulation of amyloid precursor protein catabolic process

regulation of amyloid-beta formation [inference]

negative regulation of amyloid-beta formation

negative regulation of amyloid precursor protein catabolic process [inference]

negative regulation of amyloid-beta formation

regulation of glycoprotein metabolic process [inference]

regulation of glycoprotein biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

regulation of amyloid precursor protein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

negative regulation of glycoprotein metabolic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

regulation of primary metabolic process [inference]

regulation of lipid metabolic process

regulation of protein metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of amyloid precursor protein catabolic process [inference]

negative regulation of amyloid-beta formation

negative regulation of glycoprotein metabolic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

regulation of amyloid precursor protein catabolic process

regulation of amyloid-beta formation [inference]

negative regulation of amyloid-beta formation

negative regulation of amyloid precursor protein catabolic process [inference]

negative regulation of amyloid-beta formation

regulation of glycoprotein metabolic process [inference]

regulation of glycoprotein biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

regulation of amyloid precursor protein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

negative regulation of glycoprotein metabolic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade

regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

regulation of PERK-mediated unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

negative regulation of MAPK cascade

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of ERK1 and ERK2 cascade [inference]

positive regulation of ERK1 and ERK2 cascade

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade

regulation of localization [inference]

regulation of transport [inference]

regulation of lipid transport [inference]

positive regulation of lipid transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

positive regulation of phospholipid transport [inference]

positive regulation of phospholipid efflux

regulation of sterol transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

regulation of cholesterol transport [inference]

regulation of cholesterol efflux [inference]

positive regulation of cholesterol efflux

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

regulation of phospholipid transport [inference]

regulation of phospholipid efflux [inference]

positive regulation of phospholipid efflux

positive regulation of phospholipid transport [inference]

positive regulation of phospholipid efflux

positive regulation of transport [inference]

positive regulation of lipid transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

positive regulation of phospholipid transport [inference]

positive regulation of phospholipid efflux

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

positive regulation of phagocytosis, engulfment [inference]

positive regulation of engulfment of apoptotic cell

positive regulation of apoptotic cell clearance [inference]

positive regulation of engulfment of apoptotic cell

negative regulation of transport [inference]

negative regulation of endocytosis

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

negative regulation of endocytosis

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

positive regulation of phagocytosis, engulfment [inference]

positive regulation of engulfment of apoptotic cell

positive regulation of apoptotic cell clearance [inference]

positive regulation of engulfment of apoptotic cell

regulation of phagocytosis [inference]

positive regulation of phagocytosis

positive regulation of phagocytosis, engulfment [inference]

positive regulation of engulfment of apoptotic cell

positive regulation of apoptotic cell clearance [inference]

positive regulation of engulfment of apoptotic cell

regulation of phagocytosis, engulfment [inference]

positive regulation of phagocytosis, engulfment [inference]

positive regulation of engulfment of apoptotic cell

regulation of engulfment of apoptotic cell [inference]

positive regulation of engulfment of apoptotic cell

regulation of apoptotic cell clearance [inference]

positive regulation of apoptotic cell clearance [inference]

positive regulation of engulfment of apoptotic cell

regulation of cellular localization [inference]

regulation of protein localization [inference]

positive regulation of protein localization [inference]

positive regulation of protein localization to cell surface

regulation of protein localization to cell surface [inference]

positive regulation of protein localization to cell surface

regulation of lipid localization [inference]

regulation of lipid transport [inference]

positive regulation of lipid transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

positive regulation of phospholipid transport [inference]

positive regulation of phospholipid efflux

regulation of sterol transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

regulation of cholesterol transport [inference]

regulation of cholesterol efflux [inference]

positive regulation of cholesterol efflux

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

regulation of phospholipid transport [inference]

regulation of phospholipid efflux [inference]

positive regulation of phospholipid efflux

positive regulation of phospholipid transport [inference]

positive regulation of phospholipid efflux

positive regulation of lipid localization [inference]

positive regulation of lipid transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

positive regulation of phospholipid transport [inference]

positive regulation of phospholipid efflux

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

positive regulation of phagocytosis, engulfment [inference]

positive regulation of engulfment of apoptotic cell

positive regulation of apoptotic cell clearance [inference]

positive regulation of engulfment of apoptotic cell

positive regulation of membrane invagination [inference]

positive regulation of phagocytosis, engulfment [inference]

positive regulation of engulfment of apoptotic cell

positive regulation of protein localization [inference]

positive regulation of protein localization to cell surface

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of transport [inference]

positive regulation of lipid transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

positive regulation of phospholipid transport [inference]

positive regulation of phospholipid efflux

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

positive regulation of phagocytosis, engulfment [inference]

positive regulation of engulfment of apoptotic cell

positive regulation of apoptotic cell clearance [inference]

positive regulation of engulfment of apoptotic cell

positive regulation of multicellular organismal process [inference]

positive regulation of amyloid-beta clearance

positive regulation of lipid localization [inference]

positive regulation of lipid transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

positive regulation of phospholipid transport [inference]

positive regulation of phospholipid efflux

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

negative regulation of protein metabolic process [inference]

negative regulation of amyloid precursor protein catabolic process [inference]

negative regulation of amyloid-beta formation

negative regulation of glycoprotein metabolic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of amide metabolic process [inference]

negative regulation of amyloid-beta formation

negative regulation of protein metabolic process [inference]

negative regulation of amyloid precursor protein catabolic process [inference]

negative regulation of amyloid-beta formation

negative regulation of glycoprotein metabolic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

negative regulation of cellular component organization [inference]

negative regulation of endocytosis

negative regulation of response to endoplasmic reticulum stress [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade

negative regulation of response to endoplasmic reticulum stress [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

negative regulation of transport [inference]

negative regulation of endocytosis

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade

regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

regulation of PERK-mediated unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

negative regulation of MAPK cascade

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of ERK1 and ERK2 cascade [inference]

positive regulation of ERK1 and ERK2 cascade

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade

negative regulation of response to endoplasmic reticulum stress [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

regulation of response to stress [inference]

regulation of cellular response to stress [inference]

regulation of response to endoplasmic reticulum stress [inference]

regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

regulation of PERK-mediated unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

negative regulation of response to endoplasmic reticulum stress [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

apolipoprotein A-I-mediated signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade

regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

regulation of PERK-mediated unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

negative regulation of MAPK cascade

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of ERK1 and ERK2 cascade [inference]

positive regulation of ERK1 and ERK2 cascade

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

regulation of glycoprotein biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

regulation of amyloid precursor protein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

positive regulation of phagocytosis, engulfment [inference]

positive regulation of engulfment of apoptotic cell

positive regulation of apoptotic cell clearance [inference]

positive regulation of engulfment of apoptotic cell

positive regulation of membrane invagination [inference]

positive regulation of phagocytosis, engulfment [inference]

positive regulation of engulfment of apoptotic cell

positive regulation of protein localization [inference]

positive regulation of protein localization to cell surface

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of amyloid precursor protein biosynthetic process

negative regulation of cellular component organization [inference]

negative regulation of endocytosis

negative regulation of response to endoplasmic reticulum stress [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

regulation of cellular component organization [inference]

regulation of endocytosis [inference]

negative regulation of endocytosis

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

positive regulation of phagocytosis, engulfment [inference]

positive regulation of engulfment of apoptotic cell

positive regulation of apoptotic cell clearance [inference]

positive regulation of engulfment of apoptotic cell

regulation of phagocytosis [inference]

positive regulation of phagocytosis

positive regulation of phagocytosis, engulfment [inference]

positive regulation of engulfment of apoptotic cell

positive regulation of apoptotic cell clearance [inference]

positive regulation of engulfment of apoptotic cell

regulation of phagocytosis, engulfment [inference]

positive regulation of phagocytosis, engulfment [inference]

positive regulation of engulfment of apoptotic cell

regulation of engulfment of apoptotic cell [inference]

positive regulation of engulfment of apoptotic cell

regulation of apoptotic cell clearance [inference]

positive regulation of apoptotic cell clearance [inference]

positive regulation of engulfment of apoptotic cell

negative regulation of cellular component organization [inference]

negative regulation of endocytosis

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

positive regulation of phagocytosis, engulfment [inference]

positive regulation of engulfment of apoptotic cell

positive regulation of apoptotic cell clearance [inference]

positive regulation of engulfment of apoptotic cell

positive regulation of membrane invagination [inference]

positive regulation of phagocytosis, engulfment [inference]

positive regulation of engulfment of apoptotic cell

regulation of membrane invagination [inference]

regulation of phagocytosis, engulfment [inference]

positive regulation of phagocytosis, engulfment [inference]

positive regulation of engulfment of apoptotic cell

regulation of engulfment of apoptotic cell [inference]

positive regulation of engulfment of apoptotic cell

positive regulation of membrane invagination [inference]

positive regulation of phagocytosis, engulfment [inference]

positive regulation of engulfment of apoptotic cell

regulation of cellular localization [inference]

regulation of protein localization [inference]

positive regulation of protein localization [inference]

positive regulation of protein localization to cell surface

regulation of protein localization to cell surface [inference]

positive regulation of protein localization to cell surface

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

negative regulation of endocytosis

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

positive regulation of phagocytosis, engulfment [inference]

positive regulation of engulfment of apoptotic cell

positive regulation of apoptotic cell clearance [inference]

positive regulation of engulfment of apoptotic cell

regulation of phagocytosis [inference]

positive regulation of phagocytosis

positive regulation of phagocytosis, engulfment [inference]

positive regulation of engulfment of apoptotic cell

positive regulation of apoptotic cell clearance [inference]

positive regulation of engulfment of apoptotic cell

regulation of phagocytosis, engulfment [inference]

positive regulation of phagocytosis, engulfment [inference]

positive regulation of engulfment of apoptotic cell

regulation of engulfment of apoptotic cell [inference]

positive regulation of engulfment of apoptotic cell

regulation of apoptotic cell clearance [inference]

positive regulation of apoptotic cell clearance [inference]

positive regulation of engulfment of apoptotic cell

regulation of cellular response to stress [inference]

regulation of response to endoplasmic reticulum stress [inference]

regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

regulation of PERK-mediated unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

negative regulation of response to endoplasmic reticulum stress [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of amyloid-beta clearance

regulation of amyloid-beta clearance [inference]

positive regulation of amyloid-beta clearance

regulation of biological quality [inference]

regulation of membrane lipid distribution [inference]

lipid translocation [inference]

phospholipid translocation

Displaying entries **1 - 5** of 11 in total

1

2

3

Next ›

Last »
GO Term	Evidence Code	PMID
cell junction	IDA
Golgi apparatus	IDA
ruffle membrane	ISS
intracellular membrane-bounded organelle	IBA
plasma membrane	IDA TAS	14570867 28373057

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane [inference]

early endosome membrane

bounding membrane of organelle [inference]

Golgi membrane

endosome membrane [inference]

early endosome membrane

plasma membrane region [inference]

cell projection membrane [inference]

ruffle membrane

cell junction

leading edge membrane [inference]

ruffle membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

glial cell projection

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

intracellular organelle [inference]

intracellular membrane-bounded organelle

Displaying entries **1 - 5** of 9 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
ABC-type transporter activity	IEA
phosphatidylcholine floppase activity	IBA IDA	24097981
apolipoprotein A-I receptor activity	IBA IDA	14570867
phosphatidylserine floppase activity	IBA IDA	24097981
ATP hydrolysis activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

transporter activity [inference]

lipid transporter activity [inference]

phospholipid transporter activity

phosphatidylcholine transporter activity [inference]

phosphatidylcholine floppase activity

phosphatidylserine floppase activity

intramembrane lipid transporter activity [inference]

ATPase-coupled intramembrane lipid transporter activity [inference]

floppase activity

transmembrane transporter activity [inference]

active transmembrane transporter activity [inference]

primary active transmembrane transporter activity [inference]

ATPase-coupled transmembrane transporter activity

ABC-type transporter activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

cargo receptor activity [inference]

apolipoprotein receptor activity [inference]

apolipoprotein A-I receptor activity

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

apolipoprotein A-I receptor activity

ATP-dependent activity [inference]

ATPase-coupled transmembrane transporter activity

ABC-type transporter activity

ATPase-coupled intramembrane lipid transporter activity [inference]

floppase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

ATP-binding cassette, sub-family A

Functional Category

K: Transcription
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
ABC-type transporter activity
ATP binding
lipid transporter activity
nucleotide binding

Displaying **all 6** entries
InterPro
AAA+ ATPase domain
ABC transporter A
ABC transporter-like, ATP-binding domain
ABC transporter-like, conserved site
ABC-2 type transporter, transmembrane domain
P-loop containing nucleoside triphosphate hydrolase

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0111364	Alzheimer's disease 9	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 36 in total

1

2

3

4

Next ›

Last »
Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	27403		MGI:1351646	MOUSE02687
Caenorhabditis elegans	171782		WB:WBGene00000020
Rattus norvegicus	299609		RGD:1303134	RATNO39481
Danio rerio	561460		ZFIN:ZDB-GENE-050517-6
Macaca mulatta	704976			MACMU18996
Callithrix jacchus	100393270			CALJA23948
Pongo abelii	100458264	9601_0:00471d
Nomascus leucogenys	100598971	61853_0:00366b
Sus scrofa	100623892			PIGXX18996
Cavia porcellus	100726877			CAVPO25328

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements