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quiescin Q6 sulfhydryl oxidase 1

Summary

Gene Symbol

Qsox1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

104009

PubChem

104009

Alliance of Genome Resources

MGI:1330818

Annotation

Keyword

3D-structure
Alternative splicing
Disulfide bond
FAD
Glycoprotein
Golgi apparatus
Oxidoreductase
Reference proteome
Secreted
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8BND5	Quiescin Q6 Skin sulfhydryl oxidase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein folding	IBA
negative regulation of macroautophagy	ISO
negative regulation of macroautophagy	IEA
extracellular matrix assembly	ISO
extracellular matrix assembly	IEA

GO Hierarchy

biological process

cellular process [inference]

protein folding

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

extracellular matrix assembly

extracellular structure organization [inference]

extracellular matrix organization [inference]

extracellular matrix assembly

external encapsulating structure organization [inference]

extracellular matrix organization [inference]

extracellular matrix assembly

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

negative regulation of metabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy

negative regulation of cellular metabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy

regulation of catabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy

regulation of macroautophagy [inference]

negative regulation of macroautophagy

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy

regulation of macroautophagy [inference]

negative regulation of macroautophagy

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy

negative regulation of cellular metabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy

regulation of macroautophagy [inference]

negative regulation of macroautophagy

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
Golgi membrane	ISS
Golgi membrane	ISO
Golgi membrane	IBA
extracellular space	ISS
extracellular space	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

membrane [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intercellular bridge

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
protein disulfide isomerase activity	ISS
protein disulfide isomerase activity	ISO
protein disulfide isomerase activity	IBA
flavin-dependent sulfhydryl oxidase activity	ISS
flavin-dependent sulfhydryl oxidase activity	ISO	12176051

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on a sulfur group of donors [inference]

disulfide oxidoreductase activity [inference]

protein-disulfide reductase activity [inference]

flavin-dependent sulfhydryl oxidase activity

thiol oxidase activity [inference]

flavin-dependent sulfhydryl oxidase activity

oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor [inference]

thiol oxidase activity [inference]

flavin-dependent sulfhydryl oxidase activity

isomerase activity [inference]

intramolecular oxidoreductase activity [inference]

intramolecular oxidoreductase activity, transposing S-S bonds [inference]

protein disulfide isomerase activity

catalytic activity, acting on a protein [inference]

protein disulfide isomerase activity

protein-disulfide reductase activity [inference]

flavin-dependent sulfhydryl oxidase activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

flavin adenine dinucleotide binding [inference]

FAD binding

ion binding [inference]

anion binding [inference]

flavin adenine dinucleotide binding [inference]

FAD binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

flavin adenine dinucleotide binding [inference]

FAD binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

Sulfhydryl oxidase

Functional Category

L: Replication, recombination and repair
O: Posttranslational modification, protein turnover, chaperones
P: Inorganic ion transport and metabolism

Displaying **all 3** entries
Gene Ontology
flavin-dependent sulfhydryl oxidase activity
oxidoreductase activity
thiol oxidase activity

Displaying **all 4** entries
InterPro
ERV/ALR sulfhydryl oxidase domain
Sulfhydryl oxidase, Trx-like domain
Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain
Thioredoxin domain

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:14679	VACTERL association	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 67 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	5768	Xenbase:XB-GENE-944881	HUMAN53764
Xenopus tropicalis	36464	Xenbase:XB-GENE-944881
Rattus norvegicus	84491	Xenbase:XB-GENE-944881	RATNO07040
Xenopus tropicalis	104009	Xenbase:XB-GENE-944881
Drosophila melanogaster	169714	FB:FBgn0038919
Xenopus tropicalis	178168	Xenbase:XB-GENE-944881
Xenopus tropicalis	180538	Xenbase:XB-GENE-944881
Drosophila melanogaster	227638	FB:FBgn0038919
Pan troglodytes	457558		PANTR23143
Canis lupus familiaris	490299		CANLF17149