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MIRAGE
Rap guanine nucleotide exchange factor 3
Summary
- Gene Symbol
-
- RAPGEF3
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Angiogenesis
- Guanine-nucleotide releasing factor
- Membrane
- Phosphoprotein
- Proteomics identification
- Reference proteome
- cAMP-binding
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| angiogenesis | ||
| adaptive immune response | ||
| signal transduction | ||
| adenylate cyclase-activating G protein-coupled receptor signaling pathway | ||
| Ras protein signal transduction |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane | ||
| plasma membrane | ||
| microvillus | ||
| endomembrane system | ||
| membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| guanyl-nucleotide exchange factor activity | ||
| guanyl-nucleotide exchange factor activity | ||
| guanyl-nucleotide exchange factor activity | ||
| protein binding | ||
| protein domain specific binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Rap guanine nucleotide exchange factor
- Functional Category
-
- E: Amino acid transport and metabolism
- P: Inorganic ion transport and metabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| Ras protein signal transduction |
| small GTPase-mediated signal transduction |
| InterPro |
|---|
| Cyclic nucleotide-binding domain superfamily |
| Cyclic nucleotide-binding domain |
| RmlC-like jelly roll fold |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050742 | nicotine dependence |
