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MIRAGE
glycine decarboxylase

Summary
Gene Symbol
  • Gldc
Organism
Mus musculus (house mouse)
NCBI Gene
104174
PubChem
104174
Alliance of Genome Resources
Annotation
Keyword
  • Acetylation
  • Direct protein sequencing
  • Mitochondrion
  • Oxidoreductase
  • Pyridoxal phosphate
  • Reference proteome
  • Transit peptide
Proteins
Displaying 1 entry
UniProt Protein Name
Q91W43
  • Glycine cleavage system P protein
  • Glycine decarboxylase
  • Glycine dehydrogenase (aminomethyl-transferring)
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 9 in total
GO Term Evidence Code PMID
glycine catabolic process
glycine catabolic process
glycine decarboxylation via glycine cleavage system
glycine decarboxylation via glycine cleavage system
response to methylamine
GO Hierarchy
Displaying entries 11 - 15 of 15 in total
GO Term Evidence Code PMID
pyridoxal phosphate binding
pyridoxal phosphate binding
protein homodimerization activity
protein homodimerization activity
pyridoxal binding
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
Glycine dehydrogenase
Functional Category
  • E: Amino acid transport and metabolism
  • I: Lipid transport and metabolism
  • T: Signal transduction mechanisms
Displaying all 8 entries
Gene Ontology
catalytic activity
glycine binding
glycine catabolic process
glycine decarboxylation via glycine cleavage system
glycine dehydrogenase (decarboxylating) activity
glycine metabolic process
oxidoreductase activity
pyridoxal phosphate binding
Displaying all 7 entries
InterPro
Glycine cleavage system P protein
Glycine cleavage system P-protein, N-terminal domain
Glycine dehydrogenase (decarboxylating)
Glycine dehydrogenase, C-terminal domain
Pyridoxal phosphate-dependent transferase, major domain
Pyridoxal phosphate-dependent transferase, small domain
Pyridoxal phosphate-dependent transferase
Disease
Disease Ontology
Displaying 1 entry
DO ID Disease Name Source
DOID:9268 glycine encephalopathy
Ortholog
Displaying entries 81 - 83 of 83 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
122205283 PANLE25249
123781287 URSAM20364
129047248 PONAB35396
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025