GlyCosmos Portal

Submissions

spondin 1

Summary

Gene Symbol

SPON1

Organism

Homo sapiens (human)

External Links

NCBI Gene

10418

PubChem

10418

Alliance of Genome Resources

HGNC:11252

Annotation

Keyword

3D-structure
Cell adhesion
Disulfide bond
Extracellular matrix
Glycoprotein
Metal-binding
Reference proteome
Repeat
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9HCB6	F-spondin Vascular smooth muscle cell growth-promoting factor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein processing	IEA
positive regulation of amyloid precursor protein catabolic process	IEA
cell adhesion	IBA
positive regulation of protein processing	IEA
negative regulation of amyloid-beta formation	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing

protein maturation [inference]

protein processing

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing

protein maturation [inference]

protein processing

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing

protein maturation [inference]

protein processing

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing

protein maturation [inference]

protein processing

cellular process [inference]

cell adhesion

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of protein maturation [inference]

positive regulation of protein processing

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression [inference]

positive regulation of protein maturation [inference]

positive regulation of protein processing

regulation of protein maturation [inference]

regulation of protein processing [inference]

positive regulation of protein processing

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of protein maturation [inference]

positive regulation of protein processing

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of amyloid precursor protein catabolic process [inference]

negative regulation of amyloid-beta formation

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of amide metabolic process [inference]

negative regulation of amyloid-beta formation

negative regulation of protein metabolic process [inference]

negative regulation of amyloid precursor protein catabolic process [inference]

negative regulation of amyloid-beta formation

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of protein metabolic process [inference]

positive regulation of proteolysis [inference]

positive regulation of protein processing

positive regulation of amyloid precursor protein catabolic process

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of proteolysis [inference]

positive regulation of protein processing

positive regulation of amyloid precursor protein catabolic process

positive regulation of protein maturation [inference]

positive regulation of protein processing

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of protein maturation [inference]

positive regulation of protein processing

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression [inference]

positive regulation of protein maturation [inference]

positive regulation of protein processing

regulation of protein maturation [inference]

regulation of protein processing [inference]

positive regulation of protein processing

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of protein maturation [inference]

positive regulation of protein processing

regulation of nitrogen compound metabolic process [inference]

regulation of amide metabolic process [inference]

negative regulation of amide metabolic process [inference]

negative regulation of amyloid-beta formation

regulation of amyloid-beta formation [inference]

negative regulation of amyloid-beta formation

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of amide metabolic process [inference]

negative regulation of amyloid-beta formation

negative regulation of protein metabolic process [inference]

negative regulation of amyloid precursor protein catabolic process [inference]

negative regulation of amyloid-beta formation

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of proteolysis [inference]

positive regulation of protein processing

positive regulation of amyloid precursor protein catabolic process

positive regulation of protein maturation [inference]

positive regulation of protein processing

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

positive regulation of proteolysis [inference]

positive regulation of protein processing

regulation of protein processing [inference]

positive regulation of protein processing

positive regulation of protein metabolic process [inference]

positive regulation of proteolysis [inference]

positive regulation of protein processing

positive regulation of amyloid precursor protein catabolic process

positive regulation of protein maturation [inference]

positive regulation of protein processing

negative regulation of protein metabolic process [inference]

negative regulation of amyloid precursor protein catabolic process [inference]

negative regulation of amyloid-beta formation

regulation of amyloid precursor protein catabolic process [inference]

regulation of amyloid-beta formation [inference]

negative regulation of amyloid-beta formation

negative regulation of amyloid precursor protein catabolic process [inference]

negative regulation of amyloid-beta formation

positive regulation of amyloid precursor protein catabolic process

regulation of protein maturation [inference]

regulation of protein processing [inference]

positive regulation of protein processing

positive regulation of protein maturation [inference]

positive regulation of protein processing

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression [inference]

positive regulation of protein maturation [inference]

positive regulation of protein processing

regulation of protein maturation [inference]

regulation of protein processing [inference]

positive regulation of protein processing

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of protein metabolic process [inference]

positive regulation of proteolysis [inference]

positive regulation of protein processing

positive regulation of amyloid precursor protein catabolic process

positive regulation of protein maturation [inference]

positive regulation of protein processing

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of amyloid precursor protein catabolic process [inference]

negative regulation of amyloid-beta formation

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

positive regulation of proteolysis [inference]

positive regulation of protein processing

regulation of protein processing [inference]

positive regulation of protein processing

positive regulation of protein metabolic process [inference]

positive regulation of proteolysis [inference]

positive regulation of protein processing

positive regulation of amyloid precursor protein catabolic process

positive regulation of protein maturation [inference]

positive regulation of protein processing

negative regulation of protein metabolic process [inference]

negative regulation of amyloid precursor protein catabolic process [inference]

negative regulation of amyloid-beta formation

regulation of amyloid precursor protein catabolic process [inference]

regulation of amyloid-beta formation [inference]

negative regulation of amyloid-beta formation

negative regulation of amyloid precursor protein catabolic process [inference]

negative regulation of amyloid-beta formation

positive regulation of amyloid precursor protein catabolic process

regulation of protein maturation [inference]

regulation of protein processing [inference]

positive regulation of protein processing

positive regulation of protein maturation [inference]

positive regulation of protein processing

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

positive regulation of proteolysis [inference]

positive regulation of protein processing

regulation of protein processing [inference]

positive regulation of protein processing

positive regulation of protein metabolic process [inference]

positive regulation of proteolysis [inference]

positive regulation of protein processing

positive regulation of amyloid precursor protein catabolic process

positive regulation of protein maturation [inference]

positive regulation of protein processing

negative regulation of protein metabolic process [inference]

negative regulation of amyloid precursor protein catabolic process [inference]

negative regulation of amyloid-beta formation

regulation of amyloid precursor protein catabolic process [inference]

regulation of amyloid-beta formation [inference]

negative regulation of amyloid-beta formation

negative regulation of amyloid precursor protein catabolic process [inference]

negative regulation of amyloid-beta formation

positive regulation of amyloid precursor protein catabolic process

regulation of protein maturation [inference]

regulation of protein processing [inference]

positive regulation of protein processing

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of protein metabolic process [inference]

positive regulation of proteolysis [inference]

positive regulation of protein processing

positive regulation of amyloid precursor protein catabolic process

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of proteolysis [inference]

positive regulation of protein processing

positive regulation of amyloid precursor protein catabolic process

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of protein maturation [inference]

positive regulation of protein processing

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of amyloid precursor protein catabolic process [inference]

negative regulation of amyloid-beta formation

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of amide metabolic process [inference]

negative regulation of amyloid-beta formation

negative regulation of protein metabolic process [inference]

negative regulation of amyloid precursor protein catabolic process [inference]

negative regulation of amyloid-beta formation

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of protein maturation [inference]

positive regulation of protein processing

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression [inference]

positive regulation of protein maturation [inference]

positive regulation of protein processing

regulation of protein maturation [inference]

regulation of protein processing [inference]

positive regulation of protein processing

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of protein maturation [inference]

positive regulation of protein processing

Displaying **all 4** entries
GO Term	Evidence Code	PMID
extracellular matrix	IBA
extracellular space	HDA	20551380
collagen-containing extracellular matrix	HDA	20551380
endoplasmic reticulum lumen	TAS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

external encapsulating structure [inference]

extracellular matrix

collagen-containing extracellular matrix

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

Displaying **all 4** entries
GO Term	Evidence Code	PMID
LBD domain binding	IEA
metal ion binding	IEA
extracellular matrix structural constituent	RCA	20551380
protein binding	IPI	14983046 32296183

GO Hierarchy

molecular function

structural molecule activity [inference]

extracellular matrix structural constituent

binding [inference]

protein binding

protein domain specific binding [inference]

LBD domain binding

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

International Collaboration

Acknowledgements