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sterol-C5-desaturase

Summary

Gene Symbol

SC5D

Organism

Mandrillus leucophaeus (drill)

External Links

NCBI Gene: 105528269
KEGG Gene ID: mleu:105528269
PubChem: 105528269

Annotation

Keyword

Endoplasmic reticulum
Reference proteome
Sterol biosynthesis
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A2K5Z9X8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
cholesterol biosynthetic process via lathosterol	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

small molecule metabolic process [inference]

alcohol metabolic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

secondary alcohol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

organic substance metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

secondary alcohol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

Displaying **all 2** entries
GO Term	Evidence Code	PMID
oxidoreductase activity	IEA	22301074
iron ion binding	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

iron ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Cercopithecoidea

Group Name

Fatty acid hydroxylase

Functional Category

I: Lipid transport and metabolism
U: Intracellular trafficking, secretion, and vesicular transport

Displaying entries **1 - 10** of 13 in total

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Gene Ontology
C-4 methylsterol oxidase activity
C-5 sterol desaturase activity
cholesterol biosynthetic process via lathosterol
ergosterol biosynthetic process
iron ion binding
lipid biosynthetic process
oxidoreductase activity
sphingolipid biosynthetic process
sphingolipid delta-4 desaturase activity
sphingosine hydroxylase activity

Displaying 1 entry
InterPro
Fatty acid hydroxylase

KEGG BRITE Database

Orthology

K00227

Name

Delta7-sterol 5-desaturase [EC:1.14.19.20]

References

Ortholog

Displaying entries **1 - 10** of 91 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	6309			HUMAN09905
Rattus norvegicus	114100			RATNO40302
Mus musculus	235293			MOUSE61943
Danio rerio	447891			DANRE21424
Pan troglodytes	451624			PANTR04582
Macaca mulatta	706827	9544_0:003b5b		MACMU10168
Monodelphis domestica	100030841			MONDO25518
Equus caballus	100063543			HORSE39557
Ornithorhynchus anatinus	100073392			ORNAN03178
Taeniopygia guttata	100226384			TAEGU13994

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024