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hydroxysteroid 17-beta dehydrogenase 1

Summary

Gene Symbol

HSD17B1

Organism

Mandrillus leucophaeus (drill)

External Links

NCBI Gene: 105552955
KEGG Gene ID: mleu:105552955
PubChem: 105552955

Annotation

Keyword

Cytoplasm
Oxidoreductase
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A2K5ZK21

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
estrogen biosynthetic process	IEA	22301074

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

hormone biosynthetic process [inference]

estrogen biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

estrogen biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

estrogen biosynthetic process

hormone metabolic process [inference]

estrogen metabolic process [inference]

estrogen biosynthetic process

hormone biosynthetic process [inference]

estrogen biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

estrogen biosynthetic process

estrogen metabolic process [inference]

estrogen biosynthetic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

estrogen biosynthetic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

estrogen biosynthetic process

estrogen metabolic process [inference]

estrogen biosynthetic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

estrogen biosynthetic process

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

estrogen biosynthetic process

estrogen metabolic process [inference]

estrogen biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

estrogen biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

estrogen biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

estrogen biosynthetic process

biological regulation [inference]

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

estrogen metabolic process [inference]

estrogen biosynthetic process

hormone biosynthetic process [inference]

estrogen biosynthetic process

Displaying 1 entry
GO Term	Evidence Code	PMID
cytoplasm	IEA	22301074

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

Displaying 1 entry
GO Term	Evidence Code	PMID
estradiol 17-beta-dehydrogenase [NAD(P)] activity	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

steroid dehydrogenase activity [inference]

steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

estradiol 17-beta-dehydrogenase [NAD(P)] activity

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

estradiol 17-beta-dehydrogenase [NAD(P)] activity

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00044

Name

17beta-estradiol 17-dehydrogenase [EC:1.1.1.62]

References

Rhea

17β-estradiol + NADP⁺

H⁺ + estrone + NADPH

Enzyme

1.1.1.62

PMID

17β-estradiol + NAD⁺

H⁺ + estrone + NADH

Enzyme

1.1.1.62

PMID

Ortholog

Displaying entries **11 - 20** of 69 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Oreochromis niloticus	100534524		ORENI54287
Sparus aurata	115575034		SPAAU02503
Chrysemys picta bellii	101936075		CHRPI29285
Crocodylus porosus	109323161		CROPO10156
Ornithorhynchus anatinus	114815152		ORNAN03018
Sarcophilus harrisii	100919259		SARHA08728
Erinaceus europaeus	103124302		ERIEU05442
Callithrix jacchus	100409004		CALJA34970
Cercocebus atys	105579672		CERAT29699
Macaca fascicularis	102122077		MACFA14223

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Supported by JST NBDC Grant Number JPMJND2204

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Last updated: August 19, 2024