protein O-mannosyltransferase 1

Summary
Gene Symbol
  • POMT1
Aliases
  • LGMD2K
  • dolichyl-phosphate-mannose-protein mannosyltransferase
Organism
Homo sapiens (human)
External Links
NCBI Gene
10585
GGDB ID
HGNC
9202
mRNA
map
  • 9q34.1
Protein
OMIM
KEGG Gene ID
hsa:10585
PubChem
10585
Alliance of Genome Resources
Annotation
Keyword
  • Alternative splicing
  • Congenital muscular dystrophy
  • Disease variant
  • Dystroglycanopathy
  • Endoplasmic reticulum
  • Glycoprotein
  • Glycosyltransferase
  • Limb-girdle muscular dystrophy
  • Lissencephaly
  • Metal-binding
  • Reference proteome
  • Repeat
  • Transmembrane helix
Proteins
Displaying all 2 entries
UniProt Protein Name
Q9Y6A1
  • Dolichyl-phosphate-mannose--protein mannosyltransferase 1
A0A140VKE0
Gene Ontology (GO)
GO Hierarchy
GlycoGene Database (GGDB)
KEGG BRITE Database
Orthology
K00728
Name
dolichyl-phosphate-mannose-protein mannosyltransferase [EC:2.4.1.109]
References
Reactions
Displaying 1 entry
KEGG Reaction Enzyme Acceptor Product
R07620
Disease
Disease Ontology
Displaying entries 21 - 30 of 148 in total
DO ID Disease Name Source
DOID:0060823 syndromic X-linked intellectual disability 94
DOID:0060857 septooptic dysplasia
DOID:0070247 autosomal dominant Emery-Dreifuss muscular dystrophy 2
DOID:0080033 craniometaphyseal dysplasia
DOID:0080092 myofibrillar myopathy 1
DOID:0080094 myofibrillar myopathy 3
DOID:0080102 congenital myopathy 4A
DOID:0090130 cortical dysplasia-focal epilepsy syndrome
DOID:0090132 complex cortical dysplasia with other brain malformations 7
DOID:0090137 complex cortical dysplasia with other brain malformations 1
The Human Phenotype Ontology
Displaying entries 31 - 40 of 192 in total
HPO ID HPO Term
HP:0000541 Retinal detachment
HP:0000545 Myopia
HP:0000556 Retinal dystrophy
HP:0000557 Buphthalmos
HP:0000568 Microphthalmia
HP:0000580 Pigmentary retinopathy
HP:0000587 Abnormal optic nerve morphology
HP:0000589 Coloboma
HP:0000609 Optic nerve hypoplasia
HP:0000612 Iris coloboma
Displaying all 9 entries
Disease ID Disease Name
ORPHA:370980
  • muscular dystrophy-dystroglycanopathy type B5
  • obsolete congenital muscular dystrophy without intellectual disability
ORPHA:899
  • muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A, 4
  • muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A, 7
  • muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A1
  • muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A13
  • muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A2
  • muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A3
  • muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A5
  • muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A6
  • muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A9
  • muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a, 10
  • muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a, 11
  • muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a, 12
  • muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a, 8
  • muscular dystrophy-dystroglycanopathy, type A
ORPHA:370968
  • congenital muscular dystrophy with intellectual disability
  • muscular dystrophy-dystroglycanopathy (congenital with intellectual disability), type B1
  • muscular dystrophy-dystroglycanopathy (congenital with intellectual disability), type B14
  • muscular dystrophy-dystroglycanopathy (congenital with intellectual disability), type B2
  • muscular dystrophy-dystroglycanopathy type B5
  • muscular dystrophy-dystroglycanopathy type B6
OMIM:236670
  • muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A1
ORPHA:86812
  • autosomal recessive limb-girdle muscular dystrophy type 2K
OMIM:613155
  • muscular dystrophy-dystroglycanopathy (congenital with intellectual disability), type B1
ORPHA:370959
  • muscular dystrophy-dystroglycanopathy (congenital with intellectual disability), type B1
  • muscular dystrophy-dystroglycanopathy (congenital with intellectual disability), type B14
  • muscular dystrophy-dystroglycanopathy (congenital with intellectual disability), type B2
  • muscular dystrophy-dystroglycanopathy type B5
  • obsolete congenital muscular dystrophy with cerebellar involvement
OMIM:609308
  • autosomal recessive limb-girdle muscular dystrophy type 2K
ORPHA:588
  • muscle-eye-brain disease
  • muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A1

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