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MIRAGE
centromere protein F
Summary
- Gene Symbol
-
- CENPF
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Acetylation
- Centromere
- Chromosome
- Coiled coil
- Cytoskeleton
- DNA synthesis
- Developmental protein
- Differentiation
- Kinetochore
- Methylation
- Mitosis
- Myogenesis
- Nucleus
- Phosphoprotein
- Prenylation
- Primary ciliary dyskinesia
- Proteomics identification
- Reference proteome
- Repeat
- Proteins
| UniProt | Protein Name |
|---|---|
| P49454 |
|
| A0A9L9PXU7 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| mitotic cell cycle | ||
| mitotic cell cycle | ||
| kidney development | ||
| chromosome segregation | ||
| chromosome segregation |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
negative regulation of biological process [inference]
regulation of cellular process [inference]
regulation of cellular metabolic process [inference]
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of cell cycle [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| chromosome, centromeric region | ||
| chromosome, centromeric region | ||
| kinetochore | ||
| chromatin | ||
| spindle pole |
| GO Term | Evidence Code | PMID |
|---|---|---|
| chromatin binding | ||
| protein binding | ||
| microtubule binding | ||
| protein homodimerization activity | ||
| dynein complex binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Centromere protein F
- Functional Category
-
- G: Carbohydrate transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| metaphase chromosome alignment |
| microtubule binding |
| protein homodimerization activity |
| regulation of G2/M transition of mitotic cell cycle |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110595 | Stromme syndrome |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 1063 | Xenbase:XB-GENE-1002205 | ||
| 108000 | MOUSE28677 | ||
| 257649 | RATNO06694 | ||
| 457733 | PANTR23682 | ||
| 497403 | DANRE11805 | ||
| 533089 | BOVIN08813 | ||
| 709000 | MACMU21571 | ||
| 100050180 | HORSE35261 | ||
| 100079351 | ORNAN10971 | ||
| 100222985 | TAEGU20738 |
