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C-type lectin domain family 12 member B

Summary

Gene Symbol

CLEC12B

Organism

Acinonyx jubatus (cheetah)

External Links

NCBI Gene: 106965716
KEGG Gene ID: aju:106965716
PubChem: 106965716

Annotation

Keyword

Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A6I9ZB75

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
negative regulation of signaling receptor activity	IEA	30032202
natural killer cell inhibitory signaling pathway	IEA	30032202

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-inhibiting signal transduction [inference]

immune response-inhibiting cell surface receptor signaling pathway [inference]

natural killer cell inhibitory signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-inhibiting cell surface receptor signaling pathway [inference]

natural killer cell inhibitory signaling pathway

cell surface receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-inhibiting cell surface receptor signaling pathway [inference]

natural killer cell inhibitory signaling pathway

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-inhibiting signal transduction [inference]

immune response-inhibiting cell surface receptor signaling pathway [inference]

natural killer cell inhibitory signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-inhibiting cell surface receptor signaling pathway [inference]

natural killer cell inhibitory signaling pathway

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of signaling receptor activity [inference]

negative regulation of signaling receptor activity

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of signaling receptor activity [inference]

negative regulation of signaling receptor activity

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-inhibiting signal transduction [inference]

immune response-inhibiting cell surface receptor signaling pathway [inference]

natural killer cell inhibitory signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-inhibiting cell surface receptor signaling pathway [inference]

natural killer cell inhibitory signaling pathway

regulation of cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-inhibiting signal transduction [inference]

immune response-inhibiting cell surface receptor signaling pathway [inference]

natural killer cell inhibitory signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-inhibiting cell surface receptor signaling pathway [inference]

natural killer cell inhibitory signaling pathway

cell surface receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-inhibiting cell surface receptor signaling pathway [inference]

natural killer cell inhibitory signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of signaling receptor activity [inference]

negative regulation of signaling receptor activity

regulation of molecular function [inference]

regulation of signaling receptor activity [inference]

negative regulation of signaling receptor activity

negative regulation of molecular function [inference]

negative regulation of signaling receptor activity

Displaying 1 entry
GO Term	Evidence Code	PMID
external side of plasma membrane	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

side of membrane [inference]

external side of plasma membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein phosphatase binding	IEA	30032202
signaling receptor regulator activity	IEA	30032202

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

enzyme binding [inference]

phosphatase binding [inference]

protein phosphatase binding

molecular function regulator activity [inference]

signaling receptor regulator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Carnivora

Group Name

c-type lectin domain family 12

Functional Category

M: Cell wall/membrane/envelope biogenesis
Q: Secondary metabolites biosynthesis, transport and catabolism
U: Intracellular trafficking, secretion, and vesicular transport

Displaying **all 3** entries
Gene Ontology
natural killer cell inhibitory signaling pathway
protein phosphatase binding
signaling receptor regulator activity

Displaying **all 6** entries
InterPro
C-type lectin domain family 12 member A/B
C-type lectin fold
C-type lectin-like/link domain superfamily
C-type lectin-like
Ly49-like, N-terminal
Natural killer cell receptor-like, C-type lectin-like domain

KEGG BRITE Database

Orthology

K17517

Name

C-type lectin domain family 12 member B

References

17562706

Ortholog

Displaying entries **1 - 10** of 44 in total

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Last »
Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Canis lupus familiaris	611402	9615_1:004355
Ailuropoda melanoleuca	100472446	9646_0:003fa5
Felis catus	101083012	9685_0:002249
Odobenus rosmarus divergens	101370752	9708_0:003b94
Mustela putorius furo	101686098	9669_0:004d2d
Leptonychotes weddellii	102739472	9713_0:00103d
Panthera tigris	102951146	9694_0:0020b6
Ursus maritimus	103669140	29073_0:003324
Panthera pardus	109259097	9691_0:0043e8
Neomonachus schauinslandi	110580839	29088_0:001b30

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024