GlyCosmos Portal

Annotation

Keyword

Endoplasmic reticulum
Fatty acid biosynthesis
Glycoprotein
Reference proteome
Transferase
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A6J0A5P0	3-keto acyl-CoA synthase ELOVL6 ELOVL fatty acid elongase 6 Very long chain 3-ketoacyl-CoA synthase 6 Very long chain 3-oxoacyl-CoA synthase 6

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
sphingolipid biosynthetic process	IEA	30032202
fatty acid elongation, monounsaturated fatty acid	IEA	30032202
fatty acid elongation, polyunsaturated fatty acid	IEA	30032202
fatty acid elongation, saturated fatty acid	IEA	22301074 30032202
very long-chain fatty acid biosynthetic process	IEA	22301074 30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

lipid metabolic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	IEA	30032202
endoplasmic reticulum	IEA	22301074

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying 1 entry
GO Term	Evidence Code	PMID
fatty acid elongase activity	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

acyltransferase activity, transferring groups other than amino-acyl groups [inference]

fatty acid elongase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Carnivora

Group Name

elongation of very long chain fatty acids protein 6

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying entries **1 - 10** of 14 in total

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Gene Ontology
cellular biosynthetic process
cellular lipid metabolic process
fatty acid elongase activity
fatty acid elongation, monounsaturated fatty acid
fatty acid elongation, polyunsaturated fatty acid
fatty acid elongation, saturated fatty acid
fatty acid metabolic process
lipid biosynthetic process
lipid metabolic process
long-chain fatty-acyl-CoA biosynthetic process

Displaying **all 3** entries
InterPro
ELO family, conserved site
ELO family
Elongation of very long chain fatty acids protein 6

KEGG BRITE Database

Orthology

K10203

Name

elongation of very long chain fatty acids protein 6 [EC:2.3.1.199]

References

Rhea

RHEA:32727

H⁺ + malonyl-CoA + a very-long-chain acyl-CoA

CO₂ + CoA + a very-long-chain 3-oxoacyl-CoA

Enzyme

2.3.1.199

PMID

Ortholog

Displaying entries **11 - 20** of 45 in total

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Species	Gene ID	OrthoDB
Enhydra lutris kenyoni	111155573	391180_0:0003f4
Canis lupus dingo	112671649	286419_0:0048eb
Callorhinus ursinus	112825562	34884_0:0013bf
Callorhinus ursinus	112825644	34884_0:0013e7
Puma concolor	112858425	9696_0:00232a
Vulpes vulpes	112934201	9627_0:0038b0
Ursus arctos	113255564	9644_0:0007ed
Zalophus californianus	113918343	9704_0:00054f
Zalophus californianus	113925010	9704_0:000a17
Eumetopias jubatus	114222664	34886_0:003046

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

International Collaboration

Acknowledgements