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glutamate decarboxylase 2

Summary

Gene Symbol

GAD2

Organism

Acinonyx jubatus (cheetah)

External Links

NCBI Gene: 106987549
KEGG Gene ID: aju:106987549
PubChem: 106987549

Annotation

Keyword

Cell membrane
Cell projection
Cytoplasmic vesicle
Decarboxylase
Golgi apparatus
Palmitate
Pyridoxal phosphate
Reference proteome
Synapse

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A6J0A6P1	65 kDa glutamic acid decarboxylase Glutamate decarboxylase 65 kDa isoform

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
glutamate decarboxylation to succinate	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

glutamate metabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

glutamate metabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

catabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

glutamate metabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid metabolic process [inference]

succinate metabolic process [inference]

glutamate decarboxylation to succinate

glutamate metabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

primary metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

glutamate metabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

glutamate metabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid metabolic process [inference]

succinate metabolic process [inference]

glutamate decarboxylation to succinate

glutamate metabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

glutamate metabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid metabolic process [inference]

succinate metabolic process [inference]

glutamate decarboxylation to succinate

glutamate metabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

glutamate metabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

glutamate metabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid metabolic process [inference]

succinate metabolic process [inference]

glutamate decarboxylation to succinate

glutamate metabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

Displaying 1 entry
GO Term	Evidence Code	PMID
cytoplasm	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

Displaying **all 2** entries
GO Term	Evidence Code	PMID
glutamate decarboxylase activity	IEA	30032202
pyridoxal phosphate binding	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

lyase activity [inference]

carbon-carbon lyase activity [inference]

carboxy-lyase activity [inference]

glutamate decarboxylase activity

binding [inference]

small molecule binding [inference]

vitamin binding [inference]

vitamin B6 binding [inference]

pyridoxal phosphate binding

heterocyclic compound binding [inference]

vitamin B6 binding [inference]

pyridoxal phosphate binding

ion binding [inference]

anion binding [inference]

pyridoxal phosphate binding

organic cyclic compound binding [inference]

vitamin B6 binding [inference]

pyridoxal phosphate binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Carnivora

Group Name

Pyridoxal phosphate-dependent transferase

Functional Category

E: Amino acid transport and metabolism
K: Transcription
L: Replication, recombination and repair
T: Signal transduction mechanisms

Displaying **all 8** entries
Gene Ontology
carbon-carbon lyase activity
carboxy-lyase activity
carboxylic acid metabolic process
gamma-aminobutyric acid biosynthetic process
glutamate decarboxylase activity
glutamate decarboxylation to succinate
lyase activity
pyridoxal phosphate binding

Displaying **all 4** entries
InterPro
Pyridoxal phosphate-dependent decarboxylase
Pyridoxal phosphate-dependent transferase, major domain
Pyridoxal phosphate-dependent transferase
Pyridoxal-phosphate binding site

KEGG BRITE Database

Orthology

K01580

Name

glutamate decarboxylase [EC:4.1.1.15]

References

Rhea

H⁺ + L-glutamate

CO₂ + 4-aminobutanoate

Enzyme

4.1.1.15

PMID

Ortholog

Displaying entries **21 - 30** of 45 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Lynx canadensis	115518908	61383_0:0020f6
Mustela erminea	116594354	36723_0:001d79
Phoca vitulina	116627038	9720_0:0048a4
Lontra canadensis	116861973	76717_0:004b12
Mirounga leonina	118026564	9715_0:0035c1
Halichoerus grypus	118535748	9711_0:004f37
Hyaena hyaena	120222620	95912_0:004358
Hyaena hyaena	120223570	95912_0:00458d
Puma yagouaroundi	121014696	1608482_0:00351d
Vulpes lagopus	121496657	494514_0:002672

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Last updated: December 9, 2024