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hyaluronidase 3

Summary

Gene Symbol

HYAL3

Organism

Macaca fascicularis (crab-eating macaque)

External Links

NCBI Gene: 107126372
KEGG Gene ID: mcf:107126372
PubChem: 107126372

Annotation

Keyword

Cell membrane
Cytoplasmic vesicle
Disulfide bond
Endoplasmic reticulum
Endosome
Fertilization
Glycosidase
Reference proteome
Secreted
Signal

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A2K5VH22
A0A2K5VGW3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 13 in total

1

2

3

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GO Term	Evidence Code	PMID
inflammatory response
cellular response to interleukin-1
positive regulation of acrosomal vesicle exocytosis
carbohydrate metabolic process	IEA	22301074 30032202
ovarian follicle atresia

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

mucopolysaccharide metabolic process [inference]

hyaluronan metabolic process [inference]

hyaluronan catabolic process

organonitrogen compound catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

carbohydrate derivative catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

organonitrogen compound catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

primary metabolic process [inference]

carbohydrate metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process

macromolecule metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

mucopolysaccharide metabolic process [inference]

hyaluronan metabolic process [inference]

hyaluronan catabolic process

macromolecule catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

carbohydrate derivative metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

mucopolysaccharide metabolic process [inference]

hyaluronan metabolic process [inference]

hyaluronan catabolic process

carbohydrate derivative catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

mucopolysaccharide metabolic process [inference]

hyaluronan metabolic process [inference]

hyaluronan catabolic process

organonitrogen compound catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

carbohydrate derivative catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

organonitrogen compound catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

cellular process [inference]

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV [inference]

cellular response to UV-B

reproductive process [inference]

developmental process involved in reproduction [inference]

ovarian follicle atresia

multicellular organismal reproductive process [inference]

penetration of zona pellucida

multicellular organismal process [inference]

multi-multicellular organism process [inference]

penetration of zona pellucida

developmental process [inference]

developmental process involved in reproduction [inference]

ovarian follicle atresia

anatomical structure development [inference]

animal organ development [inference]

cartilage development

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to virus

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus

response to abiotic stimulus [inference]

response to radiation [inference]

response to light stimulus [inference]

response to UV [inference]

response to UV-B [inference]

cellular response to UV-B

cellular response to UV [inference]

cellular response to UV-B

cellular response to light stimulus [inference]

cellular response to UV [inference]

cellular response to UV-B

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV [inference]

cellular response to UV-B

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV [inference]

cellular response to UV-B

response to chemical [inference]

response to organic substance [inference]

response to cytokine [inference]

response to tumor necrosis factor [inference]

cellular response to tumor necrosis factor

response to interleukin-1 [inference]

cellular response to interleukin-1

cellular response to cytokine stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

response to antibiotic

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV [inference]

cellular response to UV-B

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of secretion [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of exocytosis [inference]

positive regulation of regulated secretory pathway [inference]

positive regulation of calcium ion-dependent exocytosis [inference]

positive regulation of acrosomal vesicle exocytosis

regulation of secretion by cell [inference]

regulation of exocytosis [inference]

positive regulation of exocytosis [inference]

positive regulation of regulated secretory pathway [inference]

positive regulation of calcium ion-dependent exocytosis [inference]

positive regulation of acrosomal vesicle exocytosis

regulation of regulated secretory pathway [inference]

regulation of calcium ion-dependent exocytosis [inference]

positive regulation of calcium ion-dependent exocytosis [inference]

positive regulation of acrosomal vesicle exocytosis

regulation of acrosomal vesicle exocytosis [inference]

positive regulation of acrosomal vesicle exocytosis

positive regulation of regulated secretory pathway [inference]

positive regulation of calcium ion-dependent exocytosis [inference]

positive regulation of acrosomal vesicle exocytosis

positive regulation of secretion by cell [inference]

positive regulation of exocytosis [inference]

positive regulation of regulated secretory pathway [inference]

positive regulation of calcium ion-dependent exocytosis [inference]

positive regulation of acrosomal vesicle exocytosis

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of exocytosis [inference]

positive regulation of regulated secretory pathway [inference]

positive regulation of calcium ion-dependent exocytosis [inference]

positive regulation of acrosomal vesicle exocytosis

regulation of vesicle-mediated transport [inference]

regulation of exocytosis [inference]

positive regulation of exocytosis [inference]

positive regulation of regulated secretory pathway [inference]

positive regulation of calcium ion-dependent exocytosis [inference]

positive regulation of acrosomal vesicle exocytosis

regulation of regulated secretory pathway [inference]

regulation of calcium ion-dependent exocytosis [inference]

positive regulation of calcium ion-dependent exocytosis [inference]

positive regulation of acrosomal vesicle exocytosis

regulation of acrosomal vesicle exocytosis [inference]

positive regulation of acrosomal vesicle exocytosis

positive regulation of regulated secretory pathway [inference]

positive regulation of calcium ion-dependent exocytosis [inference]

positive regulation of acrosomal vesicle exocytosis

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of secretion by cell [inference]

positive regulation of exocytosis [inference]

positive regulation of regulated secretory pathway [inference]

positive regulation of calcium ion-dependent exocytosis [inference]

positive regulation of acrosomal vesicle exocytosis

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of exocytosis [inference]

positive regulation of regulated secretory pathway [inference]

positive regulation of calcium ion-dependent exocytosis [inference]

positive regulation of acrosomal vesicle exocytosis

positive regulation of reproductive process [inference]

positive regulation of acrosomal vesicle exocytosis

negative regulation of biological process [inference]

negative regulation of developmental process [inference]

negative regulation of ovarian follicle development

negative regulation of reproductive process [inference]

negative regulation of ovarian follicle development

regulation of developmental process [inference]

negative regulation of developmental process [inference]

negative regulation of ovarian follicle development

regulation of ovarian follicle development [inference]

negative regulation of ovarian follicle development

regulation of cellular process [inference]

positive regulation of cellular process [inference]

positive regulation of secretion by cell [inference]

positive regulation of exocytosis [inference]

positive regulation of regulated secretory pathway [inference]

positive regulation of calcium ion-dependent exocytosis [inference]

positive regulation of acrosomal vesicle exocytosis

regulation of vesicle-mediated transport [inference]

regulation of exocytosis [inference]

positive regulation of exocytosis [inference]

positive regulation of regulated secretory pathway [inference]

positive regulation of calcium ion-dependent exocytosis [inference]

positive regulation of acrosomal vesicle exocytosis

regulation of regulated secretory pathway [inference]

regulation of calcium ion-dependent exocytosis [inference]

positive regulation of calcium ion-dependent exocytosis [inference]

positive regulation of acrosomal vesicle exocytosis

regulation of acrosomal vesicle exocytosis [inference]

positive regulation of acrosomal vesicle exocytosis

positive regulation of regulated secretory pathway [inference]

positive regulation of calcium ion-dependent exocytosis [inference]

positive regulation of acrosomal vesicle exocytosis

regulation of secretion by cell [inference]

regulation of exocytosis [inference]

positive regulation of exocytosis [inference]

positive regulation of regulated secretory pathway [inference]

positive regulation of calcium ion-dependent exocytosis [inference]

positive regulation of acrosomal vesicle exocytosis

regulation of regulated secretory pathway [inference]

regulation of calcium ion-dependent exocytosis [inference]

positive regulation of calcium ion-dependent exocytosis [inference]

positive regulation of acrosomal vesicle exocytosis

regulation of acrosomal vesicle exocytosis [inference]

positive regulation of acrosomal vesicle exocytosis

positive regulation of regulated secretory pathway [inference]

positive regulation of calcium ion-dependent exocytosis [inference]

positive regulation of acrosomal vesicle exocytosis

positive regulation of secretion by cell [inference]

positive regulation of exocytosis [inference]

positive regulation of regulated secretory pathway [inference]

positive regulation of calcium ion-dependent exocytosis [inference]

positive regulation of acrosomal vesicle exocytosis

regulation of reproductive process [inference]

negative regulation of reproductive process [inference]

negative regulation of ovarian follicle development

positive regulation of reproductive process [inference]

positive regulation of acrosomal vesicle exocytosis

regulation of ovarian follicle development [inference]

negative regulation of ovarian follicle development

regulation of acrosomal vesicle exocytosis [inference]

positive regulation of acrosomal vesicle exocytosis

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
sperm midpiece
endoplasmic reticulum
acrosomal membrane
plasma membrane
extracellular region

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular region

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

secretory granule membrane [inference]

acrosomal membrane

bounding membrane of organelle [inference]

secretory granule membrane [inference]

acrosomal membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

endoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

endoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

sperm midpiece

Displaying **all 2** entries
GO Term	Evidence Code	PMID
hyalurononglucosaminidase activity	IEA	22301074 30032202
hyaluronoglucuronidase activity

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing O-glycosyl compounds [inference]

hexosaminidase activity [inference]

hyalurononglucosaminidase activity

hyaluronoglucuronidase activity

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K01197

Name

hyaluronoglucosaminidase [EC:3.2.1.35]

References

Reactions

Displaying **all 3** entries
KEGG Reaction	Enzyme	Acceptor	Product
R07824	3.2.1.35	G81393WR	G92988PL
R07825	3.2.1.35	G34586BV	G92988PL
R10905	3.2.1.35	G16235VG	G16235VG G93263XO

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Guidelines

Summary

External Links

Annotation

KEGG BRITE Database

International Collaboration

Acknowledgements